STE_MAP3K1 (Mitogen-activated protein kinase kinase kinase 1)

Total number of chains: 2
Active chains: 2
Uniprot: M3K1_HUMAN
Kinase Domain Residues: 1243 - 1508
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q13233-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MAP3K1 AF-Q13233-K1A Q13233 1235 1512 1512.0 No_ligand No_ligand Active DFGin 6.4084 13.9504 BLAminus -130.15, 175.72 58.37, 83.27 -89.89, 14.78 285.26, 76.29 -63.24, -23.0 in-in in 9.4239 Saltbr-in 2.8251 HRD-in -86.89, -42.05 63.02, -8.43 in-in-in SNCiii in-in ActLoopNT-in 2.9264 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -108.51, 136.9 APE9-dihe-na 111.22, -163.17 APE8-dihe-in -99.43, 119.44 APE8-rot-in 303.18 APE67-dihe-in -65.44, -15.34 -46.29, -43.42 APE12-dist-in 9.1435 APE11-dist-in 10.9858 APE10-dist-in 4.9965 APE9-dist-in 3.6238 None None None AF2 -1.0 1.0 1.0 A 278.0 278.0 0 32 32 0 [[1243, 1508]] 1.0 AF-Q13233-K1 STE_MAP3K1_HUMAN STE 1.8e-74 256.3 1.0 257.0 257.0 1387 1388 1389 1391 1393 1272 1294 1298 1366 1368 1367 1369.0 1431 1419 1414 1413 1412 1411 1410 1409 1408 1324 Mitogen-activated protein kinase kinase kinase 1
MAP3K1 AF-Q13233-K3A Q13233 1235 1512 1512.0 No_ligand No_ligand Active DFGin 6.5152 13.8085 BLAminus -135.18, 177.4 60.38, 77.24 -85.91, 8.52 288.31, 86.76 -64.15, -20.89 in-in in 9.4155 Saltbr-in 2.8288 HRD-in -81.6, -38.44 65.75, -17.5 in-in-in SNCiii in-in ActLoopNT-in 2.9387 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -112.32, 129.92 APE9-dihe-na 115.63, -160.62 APE8-dihe-in -104.5, 116.62 APE8-rot-in 305.13 APE67-dihe-in -60.96, -27.02 -44.38, -46.19 APE12-dist-in 9.2609 APE11-dist-in 10.8096 APE10-dist-in 4.8543 APE9-dist-in 3.9185 None None None AF2 -1.0 1.0 1.0 A 278.0 278.0 0 32 32 0 [[1243, 1508]] 1.0 AF-Q13233-K3 STE_MAP3K1_HUMAN STE 1.8e-74 256.3 1.0 257.0 257.0 1387 1388 1389 1391 1393 1272 1294 1298 1366 1368 1367 1369.0 1431 1419 1414 1413 1412 1411 1410 1409 1408 1324 Mitogen-activated protein kinase kinase kinase 1

STE_MAP3K1 (Mitogen-activated protein kinase kinase kinase 1)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q13233-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MAP3K1 M3K1_HUMAN AF-Q13233-K1A Q13233 1235 1512 1512.0 No_ligand No_ligand Active DFGin 6.4084 13.9504 BLAminus -130.15, 175.72 58.37, 83.27 -89.89, 14.78 285.26, 76.29 -63.24, -23.0 in-in in 9.4239 Saltbr-in 2.8251 HRD-in -86.89, -42.05 63.02, -8.43 in-in-in SNCiii in-in ActLoopNT-in 2.9264 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -108.51, 136.9 APE9-dihe-na 111.22, -163.17 APE8-dihe-in -99.43, 119.44 APE8-rot-in 303.18 APE67-dihe-in -65.44, -15.34 -46.29, -43.42 APE12-dist-in 9.1435 APE11-dist-in 10.9858 APE10-dist-in 4.9965 APE9-dist-in 3.6238 None None None AF2 -1.0 1.0 1.0 A 278.0 278.0 0 32 32 0 [[1243, 1508]] 1.0 AF-Q13233-K1 Homo sapiens STE_MAP3K1_HUMAN STE 1.8e-74 256.3 1.0 257.0 257.0 1387 1388 1389 1391 1393 1272 1294 1298 1366 1368 1367 1369.0 1431 1419 1414 1413 1412 1411 1410 1409 1408 1324 Mitogen-activated protein kinase kinase kinase 1
MAP3K1 M3K1_HUMAN AF-Q13233-K3A Q13233 1235 1512 1512.0 No_ligand No_ligand Active DFGin 6.5152 13.8085 BLAminus -135.18, 177.4 60.38, 77.24 -85.91, 8.52 288.31, 86.76 -64.15, -20.89 in-in in 9.4155 Saltbr-in 2.8288 HRD-in -81.6, -38.44 65.75, -17.5 in-in-in SNCiii in-in ActLoopNT-in 2.9387 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -112.32, 129.92 APE9-dihe-na 115.63, -160.62 APE8-dihe-in -104.5, 116.62 APE8-rot-in 305.13 APE67-dihe-in -60.96, -27.02 -44.38, -46.19 APE12-dist-in 9.2609 APE11-dist-in 10.8096 APE10-dist-in 4.8543 APE9-dist-in 3.9185 None None None AF2 -1.0 1.0 1.0 A 278.0 278.0 0 32 32 0 [[1243, 1508]] 1.0 AF-Q13233-K3 Homo sapiens STE_MAP3K1_HUMAN STE 1.8e-74 256.3 1.0 257.0 257.0 1387 1388 1389 1391 1393 1272 1294 1298 1366 1368 1367 1369.0 1431 1419 1414 1413 1412 1411 1410 1409 1408 1324 Mitogen-activated protein kinase kinase kinase 1

STE_MAP3K1 (Mitogen-activated protein kinase kinase kinase 1)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name