STE_MAP3K15 (Mitogen-activated protein kinase kinase kinase 15)

Total number of chains: 2
Active chains: 2
Uniprot: M3K15_HUMAN
Kinase Domain Residues: 645 - 908
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q6ZN16-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MAP3K15 AF-Q6ZN16-K1A Q6ZN16 637 916 1313.0 No_ligand No_ligand Active DFGin 6.6117 13.922 BLAminus -134.24, 175.66 61.42, 71.36 -83.22, 10.73 291.97, 91.16 -65.64, -24.0 in-in in 9.3166 Saltbr-in 2.7419 HRD-in -80.85, -42.73 67.12, 6.95 in-in-in SNCiii in-in ActLoopNT-in 2.8975 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.87, 156.45 APE9-dihe-na 92.33, 173.96 APE8-dihe-in -86.37, 121.61 APE8-rot-in 307.49 APE67-dihe-in -65.72, -17.97 -54.02, -38.84 APE12-dist-in 10.6824 APE11-dist-in 11.145 APE10-dist-in 5.2562 APE9-dist-in 3.5448 None None None AF2 -1.0 1.0 1.0 A 280.0 280.0 0 28 28 0 [[652, 908]] 1.0 AF-Q6ZN16-K1 STE_MAP3K15_HUMAN STE 3.8e-82 281.5 5.0 256.0 252.0 791 792 793 795 797 681 697 701 770 772 771 773.0 833 819 814 813 812 811 810 809 808 727 Mitogen-activated protein kinase kinase kinase 15
MAP3K15 AF-Q6ZN16-K3A Q6ZN16 637 916 1313.0 No_ligand No_ligand Active DFGin 6.0327 13.8152 BLAminus -132.25, 175.64 59.55, 77.53 -83.42, 8.31 292.52, 92.73 -62.58, -21.97 in-in in 9.046 Saltbr-in 2.7497 HRD-in -77.41, -43.07 70.08, -0.49 in-in-in SNCiii in-in ActLoopNT-in 2.9558 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.3, 143.96 APE9-dihe-na 126.41, -176.71 APE8-dihe-in -91.52, 123.64 APE8-rot-in 302.75 APE67-dihe-in -73.81, -14.38 -49.22, -40.97 APE12-dist-in 8.6752 APE11-dist-in 11.2464 APE10-dist-in 5.489 APE9-dist-in 3.2789 None None None AF2 -1.0 1.0 1.0 A 280.0 280.0 0 28 28 0 [[652, 908]] 1.0 AF-Q6ZN16-K3 STE_MAP3K15_HUMAN STE 3.8e-82 281.5 5.0 256.0 252.0 791 792 793 795 797 681 697 701 770 772 771 773.0 833 819 814 813 812 811 810 809 808 727 Mitogen-activated protein kinase kinase kinase 15

STE_MAP3K15 (Mitogen-activated protein kinase kinase kinase 15)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q6ZN16-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MAP3K15 M3K15_HUMAN AF-Q6ZN16-K1A Q6ZN16 637 916 1313.0 No_ligand No_ligand Active DFGin 6.6117 13.922 BLAminus -134.24, 175.66 61.42, 71.36 -83.22, 10.73 291.97, 91.16 -65.64, -24.0 in-in in 9.3166 Saltbr-in 2.7419 HRD-in -80.85, -42.73 67.12, 6.95 in-in-in SNCiii in-in ActLoopNT-in 2.8975 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.87, 156.45 APE9-dihe-na 92.33, 173.96 APE8-dihe-in -86.37, 121.61 APE8-rot-in 307.49 APE67-dihe-in -65.72, -17.97 -54.02, -38.84 APE12-dist-in 10.6824 APE11-dist-in 11.145 APE10-dist-in 5.2562 APE9-dist-in 3.5448 None None None AF2 -1.0 1.0 1.0 A 280.0 280.0 0 28 28 0 [[652, 908]] 1.0 AF-Q6ZN16-K1 Homo sapiens STE_MAP3K15_HUMAN STE 3.8e-82 281.5 5.0 256.0 252.0 791 792 793 795 797 681 697 701 770 772 771 773.0 833 819 814 813 812 811 810 809 808 727 Mitogen-activated protein kinase kinase kinase 15
MAP3K15 M3K15_HUMAN AF-Q6ZN16-K3A Q6ZN16 637 916 1313.0 No_ligand No_ligand Active DFGin 6.0327 13.8152 BLAminus -132.25, 175.64 59.55, 77.53 -83.42, 8.31 292.52, 92.73 -62.58, -21.97 in-in in 9.046 Saltbr-in 2.7497 HRD-in -77.41, -43.07 70.08, -0.49 in-in-in SNCiii in-in ActLoopNT-in 2.9558 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.3, 143.96 APE9-dihe-na 126.41, -176.71 APE8-dihe-in -91.52, 123.64 APE8-rot-in 302.75 APE67-dihe-in -73.81, -14.38 -49.22, -40.97 APE12-dist-in 8.6752 APE11-dist-in 11.2464 APE10-dist-in 5.489 APE9-dist-in 3.2789 None None None AF2 -1.0 1.0 1.0 A 280.0 280.0 0 28 28 0 [[652, 908]] 1.0 AF-Q6ZN16-K3 Homo sapiens STE_MAP3K15_HUMAN STE 3.8e-82 281.5 5.0 256.0 252.0 791 792 793 795 797 681 697 701 770 772 771 773.0 833 819 814 813 812 811 810 809 808 727 Mitogen-activated protein kinase kinase kinase 15

STE_MAP3K15 (Mitogen-activated protein kinase kinase kinase 15)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name