TKL_MAP3K11 (Mitogen-activated protein kinase kinase kinase 11)

Total number of chains: 2
Active chains: 2
Uniprot: M3K11_HUMAN
Kinase Domain Residues: 117 - 378
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q16584-K1A

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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q16584-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 109 - 386 0 None None Mitogen-activated protein kinase kinase kinase 11
AF-Q16584-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 109 - 386 0 None None Mitogen-activated protein kinase kinase kinase 11

TKL_MAP3K11 (Mitogen-activated protein kinase kinase kinase 11)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q16584-K1A

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
M3K11_HUMAN AF-Q16584-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 109 - 386 0 None None Mitogen-activated protein kinase kinase kinase 11 Homo sapiens
M3K11_HUMAN AF-Q16584-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 109 - 386 0 None None Mitogen-activated protein kinase kinase kinase 11 Homo sapiens

TKL_MAP3K11 (Mitogen-activated protein kinase kinase kinase 11)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism