STE_MAP2K5 (Dual specificity mitogen-activated protein kinase kinase 5)

Total number of chains: 2
Active chains: 2
Family: STE
Uniprot: MP2K5_HUMAN
Kinase Domain Residues: 166 - 419
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q13163-K1A

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PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q13163-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 158 - 427 0 None None Dual specificity mitogen-activated protein kinase kinase 5
AF-Q13163-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 158 - 427 0 None None Dual specificity mitogen-activated protein kinase kinase 5

STE_MAP2K5 (Dual specificity mitogen-activated protein kinase kinase 5)

Total number of chains: 2
Active chains: 2
Family: STE
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q13163-K1A

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UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
MP2K5_HUMAN AF-Q13163-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 158 - 427 0 None None Dual specificity mitogen-activated protein kinase kinase 5 Homo sapiens
MP2K5_HUMAN AF-Q13163-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 158 - 427 0 None None Dual specificity mitogen-activated protein kinase kinase 5 Homo sapiens

STE_MAP2K5 (Dual specificity mitogen-activated protein kinase kinase 5)

Total number of chains: 0
Active chains: 0
Family: STE
Spatial label Dihedral label Number of Chains Percent Representative

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UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism