OTHER_IKBKE (Inhibitor of nuclear factor kappa-B kinase subunit epsilon)

Total number of chains: 2
Active chains: 2
Uniprot: IKKE_HUMAN
Kinase Domain Residues: 9 - 304
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q14164-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
IKBKE AF-Q14164-K1A Q14164 1 312 716.0 No_ligand No_ligand Active DFGin 6.7187 13.6744 BLAminus -143.72, 178.6 61.91, 66.59 -79.37, 20.21 292.68, 88.79 -65.67, -20.94 in-in in 8.4053 Saltbr-in 2.6183 HRD-in -84.99, -48.65 65.45, 13.11 in-in-in SNCiii in-in ActLoopNT-in 2.9905 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -143.2, 165.5 APE9-dihe-na 117.63, -179.67 APE8-dihe-in -111.9, 132.86 APE8-rot-in 300.02 APE67-dihe-in -68.11, -26.98 -47.69, -41.16 APE12-dist-in 8.6424 APE11-dist-in 10.2568 APE10-dist-in 4.6703 APE9-dist-in 3.3599 None None None AF2 -1.0 1.0 1.0 A 312.0 312.0 0 27 27 0 [[9, 256]] 1.0 AF-Q14164-K1 OTHER_IKBKE_HUMAN STE 1e-42 152.4 1.0 218.0 218.0 156 157 158 160 162 38 55 59 132 134 133 135.0 203 183 178 177 176 175 174 173 172 87 Inhibitor of nuclear factor kappa-B kinase subunit epsilon
IKBKE AF-Q14164-K3A Q14164 1 312 716.0 No_ligand No_ligand Active DFGin 6.5473 14.1091 BLAminus -144.68, 175.81 61.0, 56.02 -70.82, 14.62 292.13, 89.05 -61.78, -25.15 in-in in 8.1991 Saltbr-in 2.6717 HRD-in -79.5, -42.13 66.9, 7.05 in-in-in SNCiii in-in ActLoopNT-in 2.8479 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.76, 157.28 APE9-dihe-na 154.51, 174.08 APE8-dihe-in -85.01, 119.62 APE8-rot-in 307.91 APE67-dihe-in -71.75, -18.82 -50.25, -42.28 APE12-dist-in 8.7594 APE11-dist-in 10.579 APE10-dist-in 7.1869 APE9-dist-in 4.8792 None None None AF2 -1.0 1.0 1.0 A 312.0 312.0 0 27 27 0 [[9, 256]] 1.0 AF-Q14164-K3 OTHER_IKBKE_HUMAN STE 1e-42 152.4 1.0 218.0 218.0 156 157 158 160 162 38 55 59 132 134 133 135.0 203 183 178 177 176 175 174 173 172 87 Inhibitor of nuclear factor kappa-B kinase subunit epsilon

OTHER_IKBKE (Inhibitor of nuclear factor kappa-B kinase subunit epsilon)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q14164-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
IKBKE IKKE_HUMAN AF-Q14164-K1A Q14164 1 312 716.0 No_ligand No_ligand Active DFGin 6.7187 13.6744 BLAminus -143.72, 178.6 61.91, 66.59 -79.37, 20.21 292.68, 88.79 -65.67, -20.94 in-in in 8.4053 Saltbr-in 2.6183 HRD-in -84.99, -48.65 65.45, 13.11 in-in-in SNCiii in-in ActLoopNT-in 2.9905 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -143.2, 165.5 APE9-dihe-na 117.63, -179.67 APE8-dihe-in -111.9, 132.86 APE8-rot-in 300.02 APE67-dihe-in -68.11, -26.98 -47.69, -41.16 APE12-dist-in 8.6424 APE11-dist-in 10.2568 APE10-dist-in 4.6703 APE9-dist-in 3.3599 None None None AF2 -1.0 1.0 1.0 A 312.0 312.0 0 27 27 0 [[9, 256]] 1.0 AF-Q14164-K1 Homo sapiens OTHER_IKBKE_HUMAN STE 1e-42 152.4 1.0 218.0 218.0 156 157 158 160 162 38 55 59 132 134 133 135.0 203 183 178 177 176 175 174 173 172 87 Inhibitor of nuclear factor kappa-B kinase subunit epsilon
IKBKE IKKE_HUMAN AF-Q14164-K3A Q14164 1 312 716.0 No_ligand No_ligand Active DFGin 6.5473 14.1091 BLAminus -144.68, 175.81 61.0, 56.02 -70.82, 14.62 292.13, 89.05 -61.78, -25.15 in-in in 8.1991 Saltbr-in 2.6717 HRD-in -79.5, -42.13 66.9, 7.05 in-in-in SNCiii in-in ActLoopNT-in 2.8479 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.76, 157.28 APE9-dihe-na 154.51, 174.08 APE8-dihe-in -85.01, 119.62 APE8-rot-in 307.91 APE67-dihe-in -71.75, -18.82 -50.25, -42.28 APE12-dist-in 8.7594 APE11-dist-in 10.579 APE10-dist-in 7.1869 APE9-dist-in 4.8792 None None None AF2 -1.0 1.0 1.0 A 312.0 312.0 0 27 27 0 [[9, 256]] 1.0 AF-Q14164-K3 Homo sapiens OTHER_IKBKE_HUMAN STE 1e-42 152.4 1.0 218.0 218.0 156 157 158 160 162 38 55 59 132 134 133 135.0 203 183 178 177 176 175 174 173 172 87 Inhibitor of nuclear factor kappa-B kinase subunit epsilon

OTHER_IKBKE (Inhibitor of nuclear factor kappa-B kinase subunit epsilon)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name