CMGC_GSK3A (Glycogen synthase kinase-3 alpha)

Total number of chains: 4
Active chains: 2
Family: CMGC
Uniprot: GSK3A_HUMAN
Kinase Domain Residues: 119 - 403
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% AF-P49840-K1A

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PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-P49840-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 111 - 411 0 None None Glycogen synthase kinase-3 alpha
AF-P49840-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 111 - 411 0 None None Glycogen synthase kinase-3 alpha
7SXGA 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii D1E Type1 103 - 445 0 PTR279 None Glycogen synthase kinase-3 alpha
7SXFA 1.94 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 6VL Type1 101 - 444 0 PTR279 None Glycogen synthase kinase-3 alpha

CMGC_GSK3A (Glycogen synthase kinase-3 alpha)

Total number of chains: 4
Active chains: 2
Family: CMGC
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% AF-P49840-K1A

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UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
GSK3A_HUMAN AF-P49840-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 111 - 411 0 None None Glycogen synthase kinase-3 alpha Homo sapiens
GSK3A_HUMAN AF-P49840-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 111 - 411 0 None None Glycogen synthase kinase-3 alpha Homo sapiens
GSK3A_HUMAN 7SXGA 2.4 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii D1E Type1 103 - 445 0 PTR279 None Glycogen synthase kinase-3 alpha Homo sapiens
GSK3A_HUMAN 7SXFA 1.94 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_iiii 6VL Type1 101 - 444 0 PTR279 None Glycogen synthase kinase-3 alpha Homo sapiens

CMGC_GSK3A (Glycogen synthase kinase-3 alpha)

Total number of chains: 0
Active chains: 0
Family: CMGC
Spatial label Dihedral label Number of Chains Percent Representative

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UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism