OTHER_EIF2AK1 (Eukaryotic translation initiation factor 2-alpha kinase 1)

Total number of chains: 2
Active chains: 2
Uniprot: E2AK1_HUMAN
Kinase Domain Residues: 167 - 583
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q9BQI3-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
EIF2AK1 AF-Q9BQI3-K1A Q9BQI3 159 591 630.0 No_ligand No_ligand Active DFGin 6.4673 14.5615 BLAminus -131.92, -174.96 56.89, 76.47 -88.07, 19.13 289.41, 80.9 -58.96, -27.63 in-in in 8.537 Saltbr-in 2.7182 HRD-in -71.02, -44.85 67.31, -7.29 in-in-in SNCiii in-in ActLoopNT-in 2.9528 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.67, 162.49 APE9-dihe-na 93.82, 165.11 APE8-dihe-in -70.82, 124.42 APE8-rot-in 291.15 APE67-dihe-in -57.27, -28.02 -49.56, -44.59 APE12-dist-in 9.1004 APE11-dist-in 11.857 APE10-dist-in 5.9348 APE9-dist-in 3.6455 None None None AF2 -1.0 1.0 1.0 A 433.0 433.0 0 40 40 0 [[48, 583]] 1.0 AF-Q9BQI3-K1 OTHER_EIF2AK1_HUMAN OTHER 1.1e-45 162.1 1.0 257.0 257.0 460 461 462 464 466 196 214 218 439 441 440 442.0 512 500 495 494 493 492 491 490 489 385 Eukaryotic translation initiation factor 2-alpha kinase 1
EIF2AK1 AF-Q9BQI3-K3A Q9BQI3 159 591 630.0 No_ligand No_ligand Active DFGin 6.3606 14.3448 BLAminus -137.24, -170.89 57.0, 58.15 -73.48, 14.84 291.76, 88.74 -60.41, -27.06 in-in in 7.7639 Saltbr-in 2.6883 HRD-in -75.49, -42.3 67.07, -9.68 in-in-in SNCiii in-in ActLoopNT-in 2.9879 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.29, 159.56 APE9-dihe-na 101.23, 170.11 APE8-dihe-in -77.19, 124.48 APE8-rot-in 287.94 APE67-dihe-in -60.9, -28.79 -48.13, -43.53 APE12-dist-in 9.1055 APE11-dist-in 11.9399 APE10-dist-in 5.9658 APE9-dist-in 3.402 None None None AF2 -1.0 1.0 1.0 A 433.0 433.0 0 40 40 0 [[48, 583]] 1.0 AF-Q9BQI3-K3 OTHER_EIF2AK1_HUMAN OTHER 1.1e-45 162.1 1.0 257.0 257.0 460 461 462 464 466 196 214 218 439 441 440 442.0 512 500 495 494 493 492 491 490 489 385 Eukaryotic translation initiation factor 2-alpha kinase 1

OTHER_EIF2AK1 (Eukaryotic translation initiation factor 2-alpha kinase 1)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q9BQI3-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
EIF2AK1 E2AK1_HUMAN AF-Q9BQI3-K1A Q9BQI3 159 591 630.0 No_ligand No_ligand Active DFGin 6.4673 14.5615 BLAminus -131.92, -174.96 56.89, 76.47 -88.07, 19.13 289.41, 80.9 -58.96, -27.63 in-in in 8.537 Saltbr-in 2.7182 HRD-in -71.02, -44.85 67.31, -7.29 in-in-in SNCiii in-in ActLoopNT-in 2.9528 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.67, 162.49 APE9-dihe-na 93.82, 165.11 APE8-dihe-in -70.82, 124.42 APE8-rot-in 291.15 APE67-dihe-in -57.27, -28.02 -49.56, -44.59 APE12-dist-in 9.1004 APE11-dist-in 11.857 APE10-dist-in 5.9348 APE9-dist-in 3.6455 None None None AF2 -1.0 1.0 1.0 A 433.0 433.0 0 40 40 0 [[48, 583]] 1.0 AF-Q9BQI3-K1 Homo sapiens OTHER_EIF2AK1_HUMAN OTHER 1.1e-45 162.1 1.0 257.0 257.0 460 461 462 464 466 196 214 218 439 441 440 442.0 512 500 495 494 493 492 491 490 489 385 Eukaryotic translation initiation factor 2-alpha kinase 1
EIF2AK1 E2AK1_HUMAN AF-Q9BQI3-K3A Q9BQI3 159 591 630.0 No_ligand No_ligand Active DFGin 6.3606 14.3448 BLAminus -137.24, -170.89 57.0, 58.15 -73.48, 14.84 291.76, 88.74 -60.41, -27.06 in-in in 7.7639 Saltbr-in 2.6883 HRD-in -75.49, -42.3 67.07, -9.68 in-in-in SNCiii in-in ActLoopNT-in 2.9879 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.29, 159.56 APE9-dihe-na 101.23, 170.11 APE8-dihe-in -77.19, 124.48 APE8-rot-in 287.94 APE67-dihe-in -60.9, -28.79 -48.13, -43.53 APE12-dist-in 9.1055 APE11-dist-in 11.9399 APE10-dist-in 5.9658 APE9-dist-in 3.402 None None None AF2 -1.0 1.0 1.0 A 433.0 433.0 0 40 40 0 [[48, 583]] 1.0 AF-Q9BQI3-K3 Homo sapiens OTHER_EIF2AK1_HUMAN OTHER 1.1e-45 162.1 1.0 257.0 257.0 460 461 462 464 466 196 214 218 439 441 440 442.0 512 500 495 494 493 492 491 490 489 385 Eukaryotic translation initiation factor 2-alpha kinase 1

OTHER_EIF2AK1 (Eukaryotic translation initiation factor 2-alpha kinase 1)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name