OTHER_DSTYK (Dual serine/threonine and tyrosine protein kinase)

Total number of chains: 2
Active chains: 2
Uniprot: DUSTY_HUMAN
Kinase Domain Residues: 648 - 908
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q6XUX3-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
DSTYK AF-Q6XUX3-K1A Q6XUX3 644 916 929.0 No_ligand No_ligand Active DFGin 5.5247 12.4997 BLAminus -135.67, 179.03 67.7, 62.8 -81.0, 10.29 308.22, 7.96 -62.27, -25.9 in-in in 7.9239 Saltbr-in 2.6751 HRD-in -75.72, -44.19 63.93, 10.48 in-in-in SNCiii in-in ActLoopNT-in 2.9065 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.46, 165.0 APE9-dihe-na 103.92, -178.75 APE8-dihe-in -87.6, 119.49 APE8-rot-in 302.61 APE67-dihe-in -66.26, -22.08 -47.21, -45.97 APE12-dist-in 8.6636 APE11-dist-in 11.3039 APE10-dist-in 5.5162 APE9-dist-in 3.5747 None None None AF2 -1.0 1.0 1.0 A 273.0 273.0 0 25 25 0 [[650, 908]] 1.0 AF-Q6XUX3-K1 OTHER_DSTYK_HUMAN TKL 4.4e-37 134.0 4.0 265.0 262.0 794 795 796 798 800 681 697 701 774 776 775 777.0 830 819 814 813 812 811 810 809 808 735 Dual serine/threonine and tyrosine protein kinase
DSTYK AF-Q6XUX3-K3A Q6XUX3 644 916 929.0 No_ligand No_ligand Active DFGin 5.5056 12.5256 BLAminus -132.96, 175.33 65.47, 65.66 -74.76, 15.89 304.88, 8.41 -60.99, -23.72 in-in in 8.9058 Saltbr-in 2.6895 HRD-in -76.85, -43.91 65.27, 12.2 in-in-in SNCiii in-in ActLoopNT-in 2.8422 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.43, 159.06 APE9-dihe-na 120.99, 175.91 APE8-dihe-in -84.2, 123.32 APE8-rot-in 299.52 APE67-dihe-in -64.52, -20.37 -51.46, -48.2 APE12-dist-in 8.5776 APE11-dist-in 11.601 APE10-dist-in 5.7229 APE9-dist-in 3.4437 None None None AF2 -1.0 1.0 1.0 A 273.0 273.0 0 25 25 0 [[650, 908]] 1.0 AF-Q6XUX3-K3 OTHER_DSTYK_HUMAN TKL 4.4e-37 134.0 4.0 265.0 262.0 794 795 796 798 800 681 697 701 774 776 775 777.0 830 819 814 813 812 811 810 809 808 735 Dual serine/threonine and tyrosine protein kinase

OTHER_DSTYK (Dual serine/threonine and tyrosine protein kinase)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q6XUX3-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
DSTYK DUSTY_HUMAN AF-Q6XUX3-K1A Q6XUX3 644 916 929.0 No_ligand No_ligand Active DFGin 5.5247 12.4997 BLAminus -135.67, 179.03 67.7, 62.8 -81.0, 10.29 308.22, 7.96 -62.27, -25.9 in-in in 7.9239 Saltbr-in 2.6751 HRD-in -75.72, -44.19 63.93, 10.48 in-in-in SNCiii in-in ActLoopNT-in 2.9065 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.46, 165.0 APE9-dihe-na 103.92, -178.75 APE8-dihe-in -87.6, 119.49 APE8-rot-in 302.61 APE67-dihe-in -66.26, -22.08 -47.21, -45.97 APE12-dist-in 8.6636 APE11-dist-in 11.3039 APE10-dist-in 5.5162 APE9-dist-in 3.5747 None None None AF2 -1.0 1.0 1.0 A 273.0 273.0 0 25 25 0 [[650, 908]] 1.0 AF-Q6XUX3-K1 Homo sapiens OTHER_DSTYK_HUMAN TKL 4.4e-37 134.0 4.0 265.0 262.0 794 795 796 798 800 681 697 701 774 776 775 777.0 830 819 814 813 812 811 810 809 808 735 Dual serine/threonine and tyrosine protein kinase
DSTYK DUSTY_HUMAN AF-Q6XUX3-K3A Q6XUX3 644 916 929.0 No_ligand No_ligand Active DFGin 5.5056 12.5256 BLAminus -132.96, 175.33 65.47, 65.66 -74.76, 15.89 304.88, 8.41 -60.99, -23.72 in-in in 8.9058 Saltbr-in 2.6895 HRD-in -76.85, -43.91 65.27, 12.2 in-in-in SNCiii in-in ActLoopNT-in 2.8422 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.43, 159.06 APE9-dihe-na 120.99, 175.91 APE8-dihe-in -84.2, 123.32 APE8-rot-in 299.52 APE67-dihe-in -64.52, -20.37 -51.46, -48.2 APE12-dist-in 8.5776 APE11-dist-in 11.601 APE10-dist-in 5.7229 APE9-dist-in 3.4437 None None None AF2 -1.0 1.0 1.0 A 273.0 273.0 0 25 25 0 [[650, 908]] 1.0 AF-Q6XUX3-K3 Homo sapiens OTHER_DSTYK_HUMAN TKL 4.4e-37 134.0 4.0 265.0 262.0 794 795 796 798 800 681 697 701 774 776 775 777.0 830 819 814 813 812 811 810 809 808 735 Dual serine/threonine and tyrosine protein kinase

OTHER_DSTYK (Dual serine/threonine and tyrosine protein kinase)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name