CMGC_CDK11B (Cyclin-dependent kinase 11B)

Total number of chains: 9
Active chains: 2
Family: CMGC
Uniprot: CD11B_HUMAN
Kinase Domain Residues: 438 - 723
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 6 66.7% 7UKZB
DFGin BLAminus 3 33.3% AF-P21127-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

PDB First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AF-P21127-K1A 430 731 795.0 No_ligand No_ligand Active DFGin 6.028 14.437 BLAminus -128.03, -177.3 53.25, 76.7 -89.25, 17.55 288.04, 82.73 -60.76, -26.86 in-in in 8.999 Saltbr-in 2.68 HRD-in -73.96, -47.13 60.92, 18.16 in-in-in SNCiii in-in ActLoopNT-in 2.88 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.43, 167.52 APE9-dihe-na 62.67, 131.95 APE8-dihe-in -55.99, 137.02 APE8-rot-in 298.67 APE67-dihe-in -69.84, -20.33 -46.1, -43.47 APE12-dist-in 13.223 APE11-dist-in 11.047 APE10-dist-in 6.664 APE9-dist-in 3.265 None None None AF2 -1.0 1.0 1.0 A 302 302 0 0 0 0 [[438, 723]] 1.0 AF-P21127-K1 CMGC_CDK11B_HUMAN CMGC 1.4e-79 273.3 1 301 301 579 580 581 583 585 467 485 489 559 561 560 562 620 607 602 601 600 599 598 597 596 517 Cyclin-dependent kinase 11B
AF-P21127-K3A 430 731 795.0 No_ligand No_ligand Active DFGin 5.626 13.566 BLAminus -125.53, -176.77 48.54, 92.44 -99.79, 14.21 292.26, 84.94 -58.47, -32.18 in-in in 8.913 Saltbr-in 2.671 HRD-in -77.26, -46.31 61.47, 15.66 in-in-in SNCiii in-in ActLoopNT-in 2.806 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.54, 162.52 APE9-dihe-na 52.73, 150.13 APE8-dihe-in -55.58, 137.46 APE8-rot-in 296.96 APE67-dihe-in -68.05, -19.94 -44.53, -41.95 APE12-dist-in 12.82 APE11-dist-in 10.659 APE10-dist-in 6.594 APE9-dist-in 3.574 None None None AF2 -1.0 1.0 1.0 A 302 302 0 0 0 0 [[438, 723]] 1.0 AF-P21127-K3 CMGC_CDK11B_HUMAN CMGC 1.4e-79 273.3 1 301 301 579 580 581 583 585 467 485 489 559 561 560 562 620 607 602 601 600 599 598 597 596 517 Cyclin-dependent kinase 11B
7UKZA 436 736 795.0 NK3:60401 Type1 Inactive DFGin 4.072 13.349 ABAminus -96.23, -48.88 -110.0, 146.16 -128.82, 27.04 279.53, 75.14 -67.25, -17.85 in-in in 9.354 Saltbr-in 2.381 HRD-in -86.45, -50.81 66.53, 10.57 in-in-in SNCiii in-in ActLoopNT-in 2.627 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.02, 166.23 APE9-dihe-na 68.7, 137.29 APE8-dihe-in -62.06, 144.96 APE8-rot-in 296.03 APE67-dihe-in -63.61, -33.68 -52.65, -42.76 APE12-dist-in 13.348 APE11-dist-in 11.455 APE10-dist-in 7.212 APE9-dist-in 3.115 None TPO595 TPO595 XRAY 2.6 0.245 0.236 A 319 294 7 0 0 0 [[438, 723]] 1.0 7ukz CMGC_CDK11B_HUMAN CMGC 1.7e-79 273.1 1 301 301 579 580 581 583 585 467 485 489 559 561 560 562 620 607 602 601 600 599 598 597 596 517 Cyclin-dependent kinase 11B
7UKZB 436 736 795.0 NK3:60401 Type1 Inactive DFGin 4.691 13.738 ABAminus -84.79, -57.34 -125.41, 150.8 -127.37, 35.1 290.38, 87.22 -63.09, -39.26 in-in in 9.753 Saltbr-in 2.757 HRD-in -88.78, -49.21 65.1, 10.56 in-in-in SNCiii in-in ActLoopNT-in 2.643 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.54, 176.81 APE9-dihe-na 65.8, 135.25 APE8-dihe-in -60.83, 142.9 APE8-rot-in 301.69 APE67-dihe-in -63.59, -42.11 -54.41, -35.26 APE12-dist-in 12.923 APE11-dist-in 11.174 APE10-dist-in 6.429 APE9-dist-in 3.174 None TPO595 TPO595 XRAY 2.6 0.245 0.236 B 319 295 6 0 0 0 [[438, 723]] 1.0 7ukz CMGC_CDK11B_HUMAN CMGC 1.7e-79 273.1 1 301 301 579 580 581 583 585 467 485 489 559 561 560 562 620 607 602 601 600 599 598 597 596 517 Cyclin-dependent kinase 11B
7UKZC 436 736 795.0 NK3:60401 Type1 Inactive DFGin 4.646 13.371 ABAminus -88.04, -54.87 -114.02, 150.19 -134.41, 29.94 289.85, 83.21 -63.34, -41.43 in-out in 9.568 Saltbr-out 3.623 HRD-in -94.69, -52.91 67.0, 11.2 out-in-in SNCoii in-in ActLoopNT-in 2.807 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.47, 160.04 APE9-dihe-na 70.29, 144.06 APE8-dihe-in -61.85, 148.89 APE8-rot-in 308.98 APE67-dihe-in -65.26, -25.37 -57.97, -38.32 APE12-dist-in 12.424 APE11-dist-in 10.821 APE10-dist-in 7.126 APE9-dist-in 3.227 None TPO595 TPO595 XRAY 2.6 0.245 0.236 C 319 293 8 0 0 0 [[438, 723]] 1.0 7ukz CMGC_CDK11B_HUMAN CMGC 1.7e-79 273.1 1 301 301 579 580 581 583 585 467 485 489 559 561 560 562 620 607 602 601 600 599 598 597 596 517 Cyclin-dependent kinase 11B
7UKZD 437 736 795.0 NK3:60401 Type1 Inactive DFGin 4.603 13.624 ABAminus -120.68, 19.95 -155.03, 143.95 -139.38, 31.81 295.34, 88.74 -63.68, -34.71 in-in in 9.538 Saltbr-in 2.655 HRD-in -96.96, -46.89 64.52, 2.75 in-in-in SNCiii in-in ActLoopNT-in 2.542 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -72.42, 170.3 APE9-dihe-na 76.85, 135.38 APE8-dihe-in -65.96, 153.07 APE8-rot-in 309.93 APE67-dihe-in -63.54, -23.22 -59.53, -40.98 APE12-dist-in 12.006 APE11-dist-in 10.447 APE10-dist-in 6.01 APE9-dist-in 3.148 None TPO595 TPO595 XRAY 2.6 0.245 0.236 D 319 291 9 0 0 0 [[438, 723]] 1.0 7ukz CMGC_CDK11B_HUMAN CMGC 1.7e-79 273.1 1 301 301 579 580 581 583 585 467 485 489 559 561 560 562 620 607 602 601 600 599 598 597 596 517 Cyclin-dependent kinase 11B
7UKZE 435 736 795.0 NK3:60401 Type1 Inactive DFGin 4.703 13.531 ABAminus -103.99, -5.44 -141.01, 145.26 -136.36, 29.3 289.91, 84.05 -63.12, -31.76 in-in in 9.162 Saltbr-in 2.379 HRD-in -79.04, -47.59 68.95, -1.32 in-in-in SNCiii in-in ActLoopNT-in 2.436 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.16, 177.63 APE9-dihe-na 68.67, 151.31 APE8-dihe-in -66.78, 150.81 APE8-rot-in 312.65 APE67-dihe-in -63.71, -40.88 -61.05, -40.0 APE12-dist-in 12.959 APE11-dist-in 11.809 APE10-dist-in 6.661 APE9-dist-in 3.318 None TPO595 TPO595 XRAY 2.6 0.245 0.236 E 319 296 6 0 0 0 [[438, 723]] 1.0 7ukz CMGC_CDK11B_HUMAN CMGC 1.7e-79 273.1 1 301 301 579 580 581 583 585 467 485 489 559 561 560 562 620 607 602 601 600 599 598 597 596 517 Cyclin-dependent kinase 11B
7UKZF 436 736 795.0 NK3:60401 Type1 Inactive DFGin 4.744 14.045 ABAminus -99.96, -10.8 -136.07, 149.53 -135.78, 43.92 284.46, 85.88 -63.4, -40.57 in-out in 9.694 Saltbr-out 4.432 HRD-in -76.05, -47.14 63.39, 6.2 out-in-in SNCoii in-in ActLoopNT-in 2.694 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.3, 171.67 APE9-dihe-na 70.2, 148.3 APE8-dihe-in -63.27, 147.05 APE8-rot-in 305.93 APE67-dihe-in -64.79, -40.08 -57.77, -40.71 APE12-dist-in 12.864 APE11-dist-in 11.62 APE10-dist-in 6.696 APE9-dist-in 3.197 None TPO595 TPO595 XRAY 2.6 0.245 0.236 F 319 294 7 0 0 0 [[438, 723]] 1.0 7ukz CMGC_CDK11B_HUMAN CMGC 1.7e-79 273.1 1 301 301 579 580 581 583 585 467 485 489 559 561 560 562 620 607 602 601 600 599 598 597 596 517 Cyclin-dependent kinase 11B
9I9IK 440 740 795.0 ADP:60801 ATPlike Inactive DFGin 4.763 14.146 BLAminus -158.41, -152.11 58.37, 65.02 -86.96, 23.61 281.98, 74.01 -65.45, -34.44 in-in in 9.348 Saltbr-in 3.025 HRD-in -87.02, -49.1 60.47, 15.99 in-in-out SNCiio in-out ActLoopNT-in 2.843 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -140.14, 178.62 APE9-dihe-na 67.65, 142.84 APE8-dihe-in -66.76, 156.24 APE8-rot-out 57.56 APE67-dihe-in -70.3, -10.82 -63.46, -38.5 APE12-dist-in 13.294 APE11-dist-in 11.398 APE10-dist-in 6.513 APE9-dist-in 3.289 None TPO595 TPO595 EM 3.5 999.0 999.0 K 442 268 35 0 0 6 [[438, 723]] 1.0 9i9i CMGC_CDK11B_HUMAN CMGC 5.1e-79 271.6 1 301 301 579 580 581 583 585 467 485 489 559 561 560 562 620 607 602 601 600 599 598 597 596 517 Cyclin-dependent kinase 11B

CMGC_CDK11B (Cyclin-dependent kinase 11B)

Total number of chains: 9
Active chains: 2
Family: CMGC
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 6 66.7% 7UKZB
DFGin BLAminus 3 33.3% AF-P21127-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CD11B_HUMAN AF-P21127-K1A P21127 430 731 795.0 No_ligand No_ligand Active DFGin 6.028 14.437 BLAminus -128.03, -177.3 53.25, 76.7 -89.25, 17.55 288.04, 82.73 -60.76, -26.86 in-in in 8.999 Saltbr-in 2.68 HRD-in -73.96, -47.13 60.92, 18.16 in-in-in SNCiii in-in ActLoopNT-in 2.88 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.43, 167.52 APE9-dihe-na 62.67, 131.95 APE8-dihe-in -55.99, 137.02 APE8-rot-in 298.67 APE67-dihe-in -69.84, -20.33 -46.1, -43.47 APE12-dist-in 13.223 APE11-dist-in 11.047 APE10-dist-in 6.664 APE9-dist-in 3.265 None None None AF2 -1.0 1.0 1.0 A 302 302 0 0 0 0 [[438, 723]] 1.0 AF-P21127-K1 Homo sapiens CMGC_CDK11B_HUMAN CMGC 1.4e-79 273.3 1 301 301 579 580 581 583 585 467 485 489 559 561 560 562 620 607 602 601 600 599 598 597 596 517 Cyclin-dependent kinase 11B
CD11B_HUMAN AF-P21127-K3A P21127 430 731 795.0 No_ligand No_ligand Active DFGin 5.626 13.566 BLAminus -125.53, -176.77 48.54, 92.44 -99.79, 14.21 292.26, 84.94 -58.47, -32.18 in-in in 8.913 Saltbr-in 2.671 HRD-in -77.26, -46.31 61.47, 15.66 in-in-in SNCiii in-in ActLoopNT-in 2.806 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.54, 162.52 APE9-dihe-na 52.73, 150.13 APE8-dihe-in -55.58, 137.46 APE8-rot-in 296.96 APE67-dihe-in -68.05, -19.94 -44.53, -41.95 APE12-dist-in 12.82 APE11-dist-in 10.659 APE10-dist-in 6.594 APE9-dist-in 3.574 None None None AF2 -1.0 1.0 1.0 A 302 302 0 0 0 0 [[438, 723]] 1.0 AF-P21127-K3 Homo sapiens CMGC_CDK11B_HUMAN CMGC 1.4e-79 273.3 1 301 301 579 580 581 583 585 467 485 489 559 561 560 562 620 607 602 601 600 599 598 597 596 517 Cyclin-dependent kinase 11B
CD11B_HUMAN 7UKZA P21127 436 736 795.0 NK3:60401 Type1 Inactive DFGin 4.072 13.349 ABAminus -96.23, -48.88 -110.0, 146.16 -128.82, 27.04 279.53, 75.14 -67.25, -17.85 in-in in 9.354 Saltbr-in 2.381 HRD-in -86.45, -50.81 66.53, 10.57 in-in-in SNCiii in-in ActLoopNT-in 2.627 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.02, 166.23 APE9-dihe-na 68.7, 137.29 APE8-dihe-in -62.06, 144.96 APE8-rot-in 296.03 APE67-dihe-in -63.61, -33.68 -52.65, -42.76 APE12-dist-in 13.348 APE11-dist-in 11.455 APE10-dist-in 7.212 APE9-dist-in 3.115 None TPO595 TPO595 XRAY 2.6 0.245 0.236 A 319 294 7 0 0 0 [[438, 723]] 1.0 7ukz Homo sapiens CMGC_CDK11B_HUMAN CMGC 1.7e-79 273.1 1 301 301 579 580 581 583 585 467 485 489 559 561 560 562 620 607 602 601 600 599 598 597 596 517 Cyclin-dependent kinase 11B
CD11B_HUMAN 7UKZB P21127 436 736 795.0 NK3:60401 Type1 Inactive DFGin 4.691 13.738 ABAminus -84.79, -57.34 -125.41, 150.8 -127.37, 35.1 290.38, 87.22 -63.09, -39.26 in-in in 9.753 Saltbr-in 2.757 HRD-in -88.78, -49.21 65.1, 10.56 in-in-in SNCiii in-in ActLoopNT-in 2.643 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.54, 176.81 APE9-dihe-na 65.8, 135.25 APE8-dihe-in -60.83, 142.9 APE8-rot-in 301.69 APE67-dihe-in -63.59, -42.11 -54.41, -35.26 APE12-dist-in 12.923 APE11-dist-in 11.174 APE10-dist-in 6.429 APE9-dist-in 3.174 None TPO595 TPO595 XRAY 2.6 0.245 0.236 B 319 295 6 0 0 0 [[438, 723]] 1.0 7ukz Homo sapiens CMGC_CDK11B_HUMAN CMGC 1.7e-79 273.1 1 301 301 579 580 581 583 585 467 485 489 559 561 560 562 620 607 602 601 600 599 598 597 596 517 Cyclin-dependent kinase 11B
CD11B_HUMAN 7UKZC P21127 436 736 795.0 NK3:60401 Type1 Inactive DFGin 4.646 13.371 ABAminus -88.04, -54.87 -114.02, 150.19 -134.41, 29.94 289.85, 83.21 -63.34, -41.43 in-out in 9.568 Saltbr-out 3.623 HRD-in -94.69, -52.91 67.0, 11.2 out-in-in SNCoii in-in ActLoopNT-in 2.807 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.47, 160.04 APE9-dihe-na 70.29, 144.06 APE8-dihe-in -61.85, 148.89 APE8-rot-in 308.98 APE67-dihe-in -65.26, -25.37 -57.97, -38.32 APE12-dist-in 12.424 APE11-dist-in 10.821 APE10-dist-in 7.126 APE9-dist-in 3.227 None TPO595 TPO595 XRAY 2.6 0.245 0.236 C 319 293 8 0 0 0 [[438, 723]] 1.0 7ukz Homo sapiens CMGC_CDK11B_HUMAN CMGC 1.7e-79 273.1 1 301 301 579 580 581 583 585 467 485 489 559 561 560 562 620 607 602 601 600 599 598 597 596 517 Cyclin-dependent kinase 11B
CD11B_HUMAN 7UKZD P21127 437 736 795.0 NK3:60401 Type1 Inactive DFGin 4.603 13.624 ABAminus -120.68, 19.95 -155.03, 143.95 -139.38, 31.81 295.34, 88.74 -63.68, -34.71 in-in in 9.538 Saltbr-in 2.655 HRD-in -96.96, -46.89 64.52, 2.75 in-in-in SNCiii in-in ActLoopNT-in 2.542 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -72.42, 170.3 APE9-dihe-na 76.85, 135.38 APE8-dihe-in -65.96, 153.07 APE8-rot-in 309.93 APE67-dihe-in -63.54, -23.22 -59.53, -40.98 APE12-dist-in 12.006 APE11-dist-in 10.447 APE10-dist-in 6.01 APE9-dist-in 3.148 None TPO595 TPO595 XRAY 2.6 0.245 0.236 D 319 291 9 0 0 0 [[438, 723]] 1.0 7ukz Homo sapiens CMGC_CDK11B_HUMAN CMGC 1.7e-79 273.1 1 301 301 579 580 581 583 585 467 485 489 559 561 560 562 620 607 602 601 600 599 598 597 596 517 Cyclin-dependent kinase 11B
CD11B_HUMAN 7UKZE P21127 435 736 795.0 NK3:60401 Type1 Inactive DFGin 4.703 13.531 ABAminus -103.99, -5.44 -141.01, 145.26 -136.36, 29.3 289.91, 84.05 -63.12, -31.76 in-in in 9.162 Saltbr-in 2.379 HRD-in -79.04, -47.59 68.95, -1.32 in-in-in SNCiii in-in ActLoopNT-in 2.436 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.16, 177.63 APE9-dihe-na 68.67, 151.31 APE8-dihe-in -66.78, 150.81 APE8-rot-in 312.65 APE67-dihe-in -63.71, -40.88 -61.05, -40.0 APE12-dist-in 12.959 APE11-dist-in 11.809 APE10-dist-in 6.661 APE9-dist-in 3.318 None TPO595 TPO595 XRAY 2.6 0.245 0.236 E 319 296 6 0 0 0 [[438, 723]] 1.0 7ukz Homo sapiens CMGC_CDK11B_HUMAN CMGC 1.7e-79 273.1 1 301 301 579 580 581 583 585 467 485 489 559 561 560 562 620 607 602 601 600 599 598 597 596 517 Cyclin-dependent kinase 11B
CD11B_HUMAN 7UKZF P21127 436 736 795.0 NK3:60401 Type1 Inactive DFGin 4.744 14.045 ABAminus -99.96, -10.8 -136.07, 149.53 -135.78, 43.92 284.46, 85.88 -63.4, -40.57 in-out in 9.694 Saltbr-out 4.432 HRD-in -76.05, -47.14 63.39, 6.2 out-in-in SNCoii in-in ActLoopNT-in 2.694 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.3, 171.67 APE9-dihe-na 70.2, 148.3 APE8-dihe-in -63.27, 147.05 APE8-rot-in 305.93 APE67-dihe-in -64.79, -40.08 -57.77, -40.71 APE12-dist-in 12.864 APE11-dist-in 11.62 APE10-dist-in 6.696 APE9-dist-in 3.197 None TPO595 TPO595 XRAY 2.6 0.245 0.236 F 319 294 7 0 0 0 [[438, 723]] 1.0 7ukz Homo sapiens CMGC_CDK11B_HUMAN CMGC 1.7e-79 273.1 1 301 301 579 580 581 583 585 467 485 489 559 561 560 562 620 607 602 601 600 599 598 597 596 517 Cyclin-dependent kinase 11B
CD11B_HUMAN 9I9IK P21127 440 740 795.0 ADP:60801 ATPlike Inactive DFGin 4.763 14.146 BLAminus -158.41, -152.11 58.37, 65.02 -86.96, 23.61 281.98, 74.01 -65.45, -34.44 in-in in 9.348 Saltbr-in 3.025 HRD-in -87.02, -49.1 60.47, 15.99 in-in-out SNCiio in-out ActLoopNT-in 2.843 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -140.14, 178.62 APE9-dihe-na 67.65, 142.84 APE8-dihe-in -66.76, 156.24 APE8-rot-out 57.56 APE67-dihe-in -70.3, -10.82 -63.46, -38.5 APE12-dist-in 13.294 APE11-dist-in 11.398 APE10-dist-in 6.513 APE9-dist-in 3.289 None TPO595 TPO595 EM 3.5 999.0 999.0 K 442 268 35 0 0 6 [[438, 723]] 1.0 9i9i Homo sapiens CMGC_CDK11B_HUMAN CMGC 5.1e-79 271.6 1 301 301 579 580 581 583 585 467 485 489 559 561 560 562 620 607 602 601 600 599 598 597 596 517 Cyclin-dependent kinase 11B

CMGC_CDK11B (Cyclin-dependent kinase 11B)

Total number of chains: 0
Active chains: 0
Family: CMGC
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

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SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name