CAMK_CAMK4 (Calcium/calmodulin-dependent protein kinase type IV)

Total number of chains: 3
Active chains: 2
Uniprot: KCC4_HUMAN
Kinase Domain Residues: 46 - 300
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% AF-Q16566-K1A
None None 1 33.3% 2W4OA

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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q16566-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 38 - 308 0 None None Calcium/calmodulin-dependent protein kinase type IV
AF-Q16566-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 38 - 308 0 None None Calcium/calmodulin-dependent protein kinase type IV
2W4OA 2.17 Inactive None‑None none-none none-out nonTYR APEdihe_aaioi APEdist_nnno DKI Type1 34 - 337 0 None None Calcium/calmodulin-dependent protein kinase type IV

CAMK_CAMK4 (Calcium/calmodulin-dependent protein kinase type IV)

Total number of chains: 5
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
None None 3 60.0% 9FQREr
DFGin BLAminus 2 40.0% AF-Q16566-K1A

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
A0A4W2D4I1_BOBOX 9FQRER 5.0 Inactive None‑None out-out out-out nonTYR APEdihe_aaioo APEdist_oioo No_ligand No_ligand 36 - 329 0 None None Calcium/calmodulin-dependent protein kinase type IV Bos indicus
A0A4W2D4I1_BOBOX 9FQRG9 5.0 Inactive None‑None out-out out-out nonTYR APEdihe_aaioo APEdist_oooo No_ligand No_ligand 36 - 329 0 None None Calcium/calmodulin-dependent protein kinase type IV Bos indicus
KCC4_HUMAN AF-Q16566-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 38 - 308 0 None None Calcium/calmodulin-dependent protein kinase type IV Homo sapiens
KCC4_HUMAN AF-Q16566-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 38 - 308 0 None None Calcium/calmodulin-dependent protein kinase type IV Homo sapiens
KCC4_HUMAN 2W4OA 2.17 Inactive None‑None none-none none-out nonTYR APEdihe_aaioi APEdist_nnno DKI Type1 34 - 337 0 None None Calcium/calmodulin-dependent protein kinase type IV Homo sapiens

CAMK_CAMK4 (Calcium/calmodulin-dependent protein kinase type IV)

Total number of chains: 2
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
None None 2 100.0% 9FQREr

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
A0A4W2D4I1_BOBOX 9FQRER 5.0 Inactive None‑None out-out out-out nonTYR APEdihe_aaioo APEdist_oioo No_ligand No_ligand 36 - 329 0 None None Calcium/calmodulin-dependent protein kinase type IV Bos indicus
A0A4W2D4I1_BOBOX 9FQRG9 5.0 Inactive None‑None out-out out-out nonTYR APEdihe_aaioo APEdist_oooo No_ligand No_ligand 36 - 329 0 None None Calcium/calmodulin-dependent protein kinase type IV Bos indicus