CAMK_CAMK1G (Calcium/calmodulin-dependent protein kinase type 1G)

Total number of chains: 4
Active chains: 2
Uniprot: KCC1G_HUMAN
Kinase Domain Residues: 23 - 277
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% AF-Q96NX5-K1A
DFGin None 2 50.0% 2JAMA

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PDB First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AF-Q96NX5-K1A 15 285 476.0 No_ligand No_ligand Active DFGin 7.056 14.338 BLAminus -126.58, 179.85 56.39, 77.72 -87.16, 15.63 287.82, 84.96 -60.45, -29.23 in-in in 9.447 Saltbr-in 2.71 HRD-in -74.86, -46.27 65.96, 8.65 in-in-in SNCiii in-in ActLoopNT-in 2.948 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.84, 169.22 APE9-dihe-na 102.92, 169.72 APE8-dihe-in -81.73, 123.98 APE8-rot-in 303.38 APE67-dihe-in -70.91, -11.9 -37.09, -50.52 APE12-dist-in 9.447 APE11-dist-in 11.742 APE10-dist-in 6.027 APE9-dist-in 3.595 None None None AF2 -1.0 1.0 1.0 A 271 271 0 0 0 0 [[23, 277]] 1.0 AF-Q96NX5-K1 CAMK_CAMK1G_HUMAN CAMK 4.6e-95 323.7 2 256 255 163 164 165 167 169 52 68 72 140 142 141 143 201 189 184 183 182 181 180 179 178 98 Calcium/calmodulin-dependent protein kinase type 1G
AF-Q96NX5-K3A 15 285 476.0 No_ligand No_ligand Active DFGin 6.525 14.257 BLAminus -129.17, -179.4 55.4, 81.07 -88.62, 13.01 293.17, 88.91 -61.06, -29.49 in-in in 9.211 Saltbr-in 2.712 HRD-in -76.58, -45.99 66.65, 0.57 in-in-in SNCiii in-in ActLoopNT-in 2.894 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.42, 177.26 APE9-dihe-na 91.59, 178.28 APE8-dihe-in -90.09, 127.83 APE8-rot-in 302.62 APE67-dihe-inflip 90.7, -32.17 -46.34, 142.38 APE12-dist-in 9.3 APE11-dist-in 11.794 APE10-dist-in 6.074 APE9-dist-in 3.483 None None None AF2 -1.0 1.0 1.0 A 271 271 0 0 0 0 [[23, 277]] 1.0 AF-Q96NX5-K3 CAMK_CAMK1G_HUMAN CAMK 4.6e-95 323.7 2 256 255 163 164 165 167 169 52 68 72 140 142 141 143 201 189 184 183 182 181 180 179 178 98 Calcium/calmodulin-dependent protein kinase type 1G
2JAMA 18 302 476.0 J60:61305 Type1 Inactive DFGin 6.54 11.213 None -126.22, -80.87 -87.21, 120.33 -158.04, 166.34 60.61, 89.98 86.24, -162.04 out-out out 12.363 Saltbr-out 7.094 HRD-out -65.72, -48.99 75.81, 136.04 out-out-out SNCooo out-out ActLoopNT-out 7.314 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -125.89, 7.58 APE9-dihe-na 74.8, 27.03 APE8-dihe-in -122.46, 113.05 APE8-rot-out 60.16 APE67-dihe-inflip 103.53, 4.1 -79.6, 161.99 APE12-dist-out 17.447 APE11-dist-out 19.304 APE10-dist-out 17.053 APE9-dist-out 17.12 None None None XRAY 1.7 0.157 0.231 A 304 279 7 0 0 1 [[23, 277]] 1.0 2jam CAMK_CAMK1G_HUMAN CAMK 7e-95 323.2 2 256 255 163 164 165 167 169 52 68 72 140 142 141 143 201 189 184 183 182 181 180 179 178 98 Calcium/calmodulin-dependent protein kinase type 1G
2JAMB 16 301 476.0 J60:61305 Type1 Inactive DFGin 6.677 11.132 None -124.15, -81.0 -87.53, 122.59 -160.87, 165.0 62.22, 92.45 89.73, -167.15 out-out out 12.39 Saltbr-out 7.106 HRD-out -61.63, -52.62 77.62, 132.57 out-out-out SNCooo out-out ActLoopNT-out 7.219 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -119.46, -1.64 APE9-dihe-na 72.11, 27.97 APE8-dihe-in -123.57, 111.56 APE8-rot-out 56.49 APE67-dihe-inflip 101.49, 1.14 -80.93, 163.71 APE12-dist-out 17.548 APE11-dist-out 19.441 APE10-dist-out 16.863 APE9-dist-out 17.082 None None None XRAY 1.7 0.157 0.231 B 304 280 7 0 0 1 [[23, 277]] 1.0 2jam CAMK_CAMK1G_HUMAN CAMK 7e-95 323.2 2 256 255 163 164 165 167 169 52 68 72 140 142 141 143 201 189 184 183 182 181 180 179 178 98 Calcium/calmodulin-dependent protein kinase type 1G

CAMK_CAMK1G (Calcium/calmodulin-dependent protein kinase type 1G)

Total number of chains: 4
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% AF-Q96NX5-K1A
DFGin None 2 50.0% 2JAMA

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SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
KCC1G_HUMAN AF-Q96NX5-K1A Q96NX5 15 285 476.0 No_ligand No_ligand Active DFGin 7.056 14.338 BLAminus -126.58, 179.85 56.39, 77.72 -87.16, 15.63 287.82, 84.96 -60.45, -29.23 in-in in 9.447 Saltbr-in 2.71 HRD-in -74.86, -46.27 65.96, 8.65 in-in-in SNCiii in-in ActLoopNT-in 2.948 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.84, 169.22 APE9-dihe-na 102.92, 169.72 APE8-dihe-in -81.73, 123.98 APE8-rot-in 303.38 APE67-dihe-in -70.91, -11.9 -37.09, -50.52 APE12-dist-in 9.447 APE11-dist-in 11.742 APE10-dist-in 6.027 APE9-dist-in 3.595 None None None AF2 -1.0 1.0 1.0 A 271 271 0 0 0 0 [[23, 277]] 1.0 AF-Q96NX5-K1 Homo sapiens CAMK_CAMK1G_HUMAN CAMK 4.6e-95 323.7 2 256 255 163 164 165 167 169 52 68 72 140 142 141 143 201 189 184 183 182 181 180 179 178 98 Calcium/calmodulin-dependent protein kinase type 1G
KCC1G_HUMAN AF-Q96NX5-K3A Q96NX5 15 285 476.0 No_ligand No_ligand Active DFGin 6.525 14.257 BLAminus -129.17, -179.4 55.4, 81.07 -88.62, 13.01 293.17, 88.91 -61.06, -29.49 in-in in 9.211 Saltbr-in 2.712 HRD-in -76.58, -45.99 66.65, 0.57 in-in-in SNCiii in-in ActLoopNT-in 2.894 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.42, 177.26 APE9-dihe-na 91.59, 178.28 APE8-dihe-in -90.09, 127.83 APE8-rot-in 302.62 APE67-dihe-inflip 90.7, -32.17 -46.34, 142.38 APE12-dist-in 9.3 APE11-dist-in 11.794 APE10-dist-in 6.074 APE9-dist-in 3.483 None None None AF2 -1.0 1.0 1.0 A 271 271 0 0 0 0 [[23, 277]] 1.0 AF-Q96NX5-K3 Homo sapiens CAMK_CAMK1G_HUMAN CAMK 4.6e-95 323.7 2 256 255 163 164 165 167 169 52 68 72 140 142 141 143 201 189 184 183 182 181 180 179 178 98 Calcium/calmodulin-dependent protein kinase type 1G
KCC1G_HUMAN 2JAMA Q96NX5 18 302 476.0 J60:61305 Type1 Inactive DFGin 6.54 11.213 None -126.22, -80.87 -87.21, 120.33 -158.04, 166.34 60.61, 89.98 86.24, -162.04 out-out out 12.363 Saltbr-out 7.094 HRD-out -65.72, -48.99 75.81, 136.04 out-out-out SNCooo out-out ActLoopNT-out 7.314 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -125.89, 7.58 APE9-dihe-na 74.8, 27.03 APE8-dihe-in -122.46, 113.05 APE8-rot-out 60.16 APE67-dihe-inflip 103.53, 4.1 -79.6, 161.99 APE12-dist-out 17.447 APE11-dist-out 19.304 APE10-dist-out 17.053 APE9-dist-out 17.12 None None None XRAY 1.7 0.157 0.231 A 304 279 7 0 0 1 [[23, 277]] 1.0 2jam Homo sapiens CAMK_CAMK1G_HUMAN CAMK 7e-95 323.2 2 256 255 163 164 165 167 169 52 68 72 140 142 141 143 201 189 184 183 182 181 180 179 178 98 Calcium/calmodulin-dependent protein kinase type 1G
KCC1G_HUMAN 2JAMB Q96NX5 16 301 476.0 J60:61305 Type1 Inactive DFGin 6.677 11.132 None -124.15, -81.0 -87.53, 122.59 -160.87, 165.0 62.22, 92.45 89.73, -167.15 out-out out 12.39 Saltbr-out 7.106 HRD-out -61.63, -52.62 77.62, 132.57 out-out-out SNCooo out-out ActLoopNT-out 7.219 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -119.46, -1.64 APE9-dihe-na 72.11, 27.97 APE8-dihe-in -123.57, 111.56 APE8-rot-out 56.49 APE67-dihe-inflip 101.49, 1.14 -80.93, 163.71 APE12-dist-out 17.548 APE11-dist-out 19.441 APE10-dist-out 16.863 APE9-dist-out 17.082 None None None XRAY 1.7 0.157 0.231 B 304 280 7 0 0 1 [[23, 277]] 1.0 2jam Homo sapiens CAMK_CAMK1G_HUMAN CAMK 7e-95 323.2 2 256 255 163 164 165 167 169 52 68 72 140 142 141 143 201 189 184 183 182 181 180 179 178 98 Calcium/calmodulin-dependent protein kinase type 1G

CAMK_CAMK1G (Calcium/calmodulin-dependent protein kinase type 1G)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative

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SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name