| Gene | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACVRL1 | AF-P37023-K1A | P37023 | 194 | 499 | 503.0 | No_ligand | No_ligand | Active | DFGin | 6.6371 | 13.2251 | BLAminus | -125.9, 178.53 | 55.6, 69.32 | -87.18, 13.23 | 299.46, 176.29 | -63.45, -18.11 | in-in | in | 8.1981 | Saltbr-in | 2.7085 | HRD-in | -74.51, -40.12 | 65.67, -18.23 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8707 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -121.73, 170.02 | APE9-dihe-na | 100.1, -179.36 | APE8-dihe-in | -79.37, 114.79 | APE8-rot-in | 305.67 | APE67-dihe-in | -60.55, -25.81 | -44.92, -42.66 | APE12-dist-in | 11.284 | APE11-dist-in | 12.0229 | APE10-dist-in | 6.1844 | APE9-dist-in | 3.8991 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 306.0 | 306.0 | 0 | 32 | 32 | 0 | [[200, 491]] | 1.0 | AF-P37023-K1 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | AF-P37023-K3A | P37023 | 194 | 499 | 503.0 | No_ligand | No_ligand | Active | DFGin | 6.5567 | 13.1446 | BLAminus | -126.65, -177.52 | 56.86, 49.0 | -73.45, 1.99 | 298.85, 178.6 | -60.09, -18.55 | in-in | in | 7.9868 | Saltbr-in | 2.7023 | HRD-in | -76.48, -38.56 | 65.65, -26.13 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8062 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -114.75, 161.78 | APE9-dihe-na | 118.2, 172.43 | APE8-dihe-in | -85.98, 116.23 | APE8-rot-in | 302.25 | APE67-dihe-in | -63.07, -19.36 | -41.14, -46.72 | APE12-dist-in | 10.715 | APE11-dist-in | 11.2332 | APE10-dist-in | 5.4576 | APE9-dist-in | 3.8094 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 306.0 | 306.0 | 0 | 32 | 32 | 0 | [[200, 491]] | 1.0 | AF-P37023-K3 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | 3MY0A | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2559 | 13.8168 | BLAminus | -125.41, 179.58 | 64.23, 80.18 | -93.04, 16.17 | 280.44, 59.18 | -60.43, -25.79 | in-out | in | 8.8089 | Saltbr-out | 4.6541 | HRD-in | -75.03, -54.04 | 76.35, -2.61 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.8978 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -118.09, 170.06 | APE9-dihe-na | -54.91, 151.81 | APE8-dihe-in | -58.19, 127.96 | APE8-rot-in | 308.6 | APE67-dihe-in | -54.84, -26.12 | -60.37, -41.45 | APE12-dist-in | 10.7017 | APE11-dist-out | 6.8562 | APE10-dist-out | 9.1652 | APE9-dist-in | 3.59 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | A | 305.0 | 295.0 | 4 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | 3MY0B | P37023 | 195 | 494 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.282 | 13.8378 | BLAminus | -125.5, 176.91 | 65.33, 80.72 | -94.34, 16.94 | 280.76, 60.24 | -60.74, -22.47 | in-out | in | 8.7908 | Saltbr-out | 4.6638 | HRD-in | -70.36, -57.83 | 78.84, -3.15 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9084 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -118.81, 172.96 | APE9-dihe-na | -55.33, 155.22 | APE8-dihe-in | -58.33, 129.61 | APE8-rot-in | 310.35 | APE67-dihe-in | -57.43, -24.18 | -60.83, -40.24 | APE12-dist-in | 10.8595 | APE11-dist-out | 7.0191 | APE10-dist-out | 9.2706 | APE9-dist-in | 3.7536 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | B | 305.0 | 295.0 | 5 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | 3MY0C | P37023 | 195 | 492 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2906 | 13.8525 | BLAminus | -125.28, 179.94 | 63.19, 82.04 | -96.22, 18.21 | 279.16, 60.64 | -59.55, -26.97 | in-out | in | 8.7777 | Saltbr-out | 4.4878 | HRD-in | -74.47, -54.77 | 76.15, -2.86 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9644 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -127.27, 173.58 | APE9-dihe-na | -58.8, 157.05 | APE8-dihe-in | -60.34, 122.64 | APE8-rot-in | 302.84 | APE67-dihe-in | -56.55, -26.73 | -54.35, -41.84 | APE12-dist-in | 10.3375 | APE11-dist-out | 6.6753 | APE10-dist-out | 8.8911 | APE9-dist-in | 3.7201 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | C | 305.0 | 298.0 | 0 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | 3MY0D | P37023 | 195 | 491 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2484 | 13.8247 | BLAminus | -124.95, 176.57 | 67.57, 82.38 | -95.52, 17.16 | 280.1, 61.89 | -61.6, -24.06 | in-out | in | 8.775 | Saltbr-out | 4.6481 | HRD-in | -73.21, -54.97 | 76.6, -0.66 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9806 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -125.66, 176.14 | APE9-dihe-na | -59.34, 158.81 | APE8-dihe-in | -61.41, 119.86 | APE8-rot-in | 302.71 | APE67-dihe-in | -53.75, -26.66 | -53.87, -42.29 | APE12-dist-in | 10.4503 | APE11-dist-out | 6.5982 | APE10-dist-out | 8.884 | APE9-dist-in | 3.6726 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | D | 305.0 | 297.0 | 0 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | 3MY0E | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2731 | 13.8294 | BLAminus | -126.51, 175.94 | 66.5, 79.46 | -94.66, 19.24 | 281.15, 60.34 | -60.84, -27.1 | in-out | in | 8.7803 | Saltbr-out | 4.5178 | HRD-in | -75.02, -53.91 | 76.92, -5.86 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9223 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -120.98, 170.65 | APE9-dihe-na | -54.41, 156.64 | APE8-dihe-in | -61.09, 130.67 | APE8-rot-in | 310.34 | APE67-dihe-in | -58.81, -25.77 | -58.5, -39.08 | APE12-dist-in | 10.928 | APE11-dist-out | 7.0909 | APE10-dist-out | 9.3099 | APE9-dist-in | 3.7904 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | E | 305.0 | 293.0 | 6 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | 3MY0F | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.3087 | 13.8419 | BLAminus | -125.61, 177.33 | 65.02, 84.05 | -97.9, 17.92 | 280.6, 59.22 | -59.08, -26.58 | in-out | in | 8.7809 | Saltbr-out | 4.6093 | HRD-in | -73.07, -56.83 | 77.8, -3.03 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9034 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -119.08, 173.21 | APE9-dihe-na | -57.72, 152.44 | APE8-dihe-in | -56.61, 129.17 | APE8-rot-in | 309.69 | APE67-dihe-in | -57.05, -27.53 | -60.31, -37.52 | APE12-dist-in | 9.9689 | APE11-dist-out | 6.4883 | APE10-dist-out | 8.7085 | APE9-dist-in | 3.4413 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | F | 305.0 | 293.0 | 6 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | 3MY0G | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.3062 | 13.8266 | BLAminus | -125.88, 178.86 | 65.59, 83.12 | -96.91, 17.15 | 278.99, 62.26 | -59.85, -26.27 | in-out | in | 8.7684 | Saltbr-out | 4.5724 | HRD-in | -71.05, -57.49 | 79.48, -2.73 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9045 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -119.13, 171.83 | APE9-dihe-na | -53.51, 156.9 | APE8-dihe-in | -60.69, 129.01 | APE8-rot-in | 313.4 | APE67-dihe-in | -55.21, -26.28 | -57.22, -40.58 | APE12-dist-in | 10.6441 | APE11-dist-out | 6.9623 | APE10-dist-out | 9.1789 | APE9-dist-in | 3.6981 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | G | 305.0 | 293.0 | 6 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | 3MY0H | P37023 | 195 | 492 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2793 | 13.8772 | BLAminus | -127.12, 175.15 | 67.39, 80.98 | -93.48, 16.98 | 280.44, 59.29 | -58.69, -25.99 | in-out | in | 8.8145 | Saltbr-out | 4.6188 | HRD-in | -73.23, -54.57 | 76.21, -2.71 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.8992 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -126.72, 171.23 | APE9-dihe-na | -56.88, 158.03 | APE8-dihe-in | -60.18, 123.4 | APE8-rot-in | 306.72 | APE67-dihe-in | -54.25, -24.74 | -55.41, -42.39 | APE12-dist-in | 10.4908 | APE11-dist-out | 6.7371 | APE10-dist-out | 8.896 | APE9-dist-in | 3.7941 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | H | 305.0 | 293.0 | 5 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | 3MY0I | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.299 | 13.8413 | BLAminus | -127.43, 177.75 | 64.38, 81.53 | -95.75, 18.19 | 279.47, 62.86 | -61.72, -24.11 | in-out | in | 8.8069 | Saltbr-out | 4.6533 | HRD-in | -70.96, -57.86 | 78.33, -0.93 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.8478 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -117.48, 172.9 | APE9-dihe-na | -54.6, 153.3 | APE8-dihe-in | -58.52, 129.27 | APE8-rot-in | 311.22 | APE67-dihe-in | -54.61, -26.28 | -60.94, -38.76 | APE12-dist-in | 10.4833 | APE11-dist-out | 6.7406 | APE10-dist-out | 8.9697 | APE9-dist-in | 3.4815 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | I | 305.0 | 292.0 | 7 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | 3MY0J | P37023 | 200 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2755 | 13.8404 | BLAminus | -127.36, 177.46 | 65.38, 81.12 | -94.87, 16.49 | 280.58, 61.3 | -59.74, -24.71 | in-out | in | 8.786 | Saltbr-out | 4.5936 | HRD-in | -72.33, -56.82 | 78.64, -2.73 | out-in-none | SNCoin | in-none | ActLoopNT-in | 2.9157 | ActLoopCT-none | nonTYR | APEdihe_aannn | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 999.0 | APE8-rot-none | 999.0 | APE67-dihe-none | 999.0, -27.97 | 999.0, 999.0 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | J | 305.0 | 252.0 | 42 | 32 | 12 | 20 | [[200, 491]] | 1.0 | 3my0 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | 3MY0K | P37023 | 195 | 492 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2815 | 13.8283 | BLAminus | -128.06, 176.75 | 65.43, 82.77 | -95.72, 16.46 | 281.05, 60.32 | -60.13, -25.23 | in-out | in | 8.7674 | Saltbr-out | 4.5992 | HRD-in | -72.66, -56.49 | 79.37, -3.81 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9204 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -117.86, 173.18 | APE9-dihe-na | -55.66, 154.25 | APE8-dihe-in | -59.56, 129.15 | APE8-rot-in | 308.9 | APE67-dihe-in | -60.72, -26.44 | -60.12, -41.3 | APE12-dist-in | 10.0058 | APE11-dist-out | 6.0181 | APE10-dist-out | 9.0788 | APE9-dist-in | 3.5094 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | K | 305.0 | 261.0 | 37 | 32 | 23 | 9 | [[200, 491]] | 1.0 | 3my0 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | 3MY0L | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2573 | 13.8445 | BLAminus | -127.8, 177.54 | 64.87, 80.43 | -93.78, 16.91 | 280.46, 60.74 | -60.32, -23.66 | in-out | in | 8.8101 | Saltbr-out | 4.5353 | HRD-in | -74.09, -56.52 | 78.77, -3.63 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.882 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -119.49, 172.18 | APE9-dihe-na | -52.86, 155.13 | APE8-dihe-in | -61.31, 128.43 | APE8-rot-in | 309.91 | APE67-dihe-in | -61.26, -26.28 | -57.4, -34.74 | APE12-dist-in | 10.5176 | APE11-dist-out | 6.9861 | APE10-dist-out | 9.0891 | APE9-dist-in | 3.8055 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | L | 305.0 | 295.0 | 4 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | 3MY0M | P37023 | 195 | 494 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.3078 | 13.8516 | BLAminus | -124.52, 176.18 | 66.21, 82.42 | -94.8, 15.37 | 280.18, 60.8 | -60.1, -22.59 | in-out | in | 8.7838 | Saltbr-out | 4.5811 | HRD-in | -74.74, -52.47 | 77.56, -4.84 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9251 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -118.36, 173.56 | APE9-dihe-na | -55.01, 156.87 | APE8-dihe-in | -59.73, 130.8 | APE8-rot-in | 309.42 | APE67-dihe-in | -53.12, -26.51 | -60.99, -39.7 | APE12-dist-in | 10.5972 | APE11-dist-out | 6.9008 | APE10-dist-out | 9.0514 | APE9-dist-in | 3.5862 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | M | 305.0 | 297.0 | 3 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | 3MY0N | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2677 | 13.8495 | BLAminus | -125.99, 176.35 | 64.32, 84.23 | -94.91, 15.92 | 278.24, 61.08 | -58.16, -28.3 | in-out | in | 8.8005 | Saltbr-out | 4.5539 | HRD-in | -76.2, -55.28 | 77.66, -3.01 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9687 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -126.77, 175.42 | APE9-dihe-na | -61.21, 157.6 | APE8-dihe-in | -60.19, 120.19 | APE8-rot-in | 304.5 | APE67-dihe-in | -55.16, -25.15 | -51.9, -42.07 | APE12-dist-in | 10.4066 | APE11-dist-out | 6.6664 | APE10-dist-out | 8.9779 | APE9-dist-in | 3.7119 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | N | 305.0 | 299.0 | 0 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | 3MY0O | P37023 | 195 | 490 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2446 | 13.8256 | BLAminus | -124.42, 177.92 | 63.77, 82.48 | -95.09, 16.7 | 280.92, 59.16 | -59.26, -25.66 | in-out | in | 8.7688 | Saltbr-out | 4.6292 | HRD-in | -72.59, -55.78 | 77.27, -1.86 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9566 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -124.59, 174.26 | APE9-dihe-na | -59.01, 155.79 | APE8-dihe-in | -58.46, 122.31 | APE8-rot-in | 303.34 | APE67-dihe-in | -56.92, -30.83 | -54.23, -39.39 | APE12-dist-in | 10.5849 | APE11-dist-out | 6.8696 | APE10-dist-out | 9.1142 | APE9-dist-in | 3.8729 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | O | 305.0 | 296.0 | 1 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | 3MY0P | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2781 | 13.8312 | BLAminus | -126.85, 176.63 | 66.27, 80.08 | -94.49, 17.72 | 281.11, 60.29 | -59.62, -26.74 | in-out | in | 8.7787 | Saltbr-out | 4.604 | HRD-in | -73.25, -56.52 | 77.99, -3.26 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9979 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -153.25, 165.67 | APE9-dihe-na | -62.04, 116.18 | APE8-dihe-in | -38.19, 117.05 | APE8-rot-in | 315.84 | APE67-dihe-in | -54.95, -25.14 | -4.8, -73.53 | APE12-dist-in | 10.4624 | APE11-dist-out | 7.286 | APE10-dist-out | 8.3619 | APE9-dist-in | 3.0952 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | P | 305.0 | 290.0 | 9 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | 3MY0Q | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.3071 | 13.8327 | BLAminus | -126.7, 177.0 | 66.0, 82.27 | -96.39, 17.62 | 281.0, 60.69 | -60.74, -24.24 | in-out | in | 8.7826 | Saltbr-out | 4.5677 | HRD-in | -71.51, -56.19 | 77.55, -1.78 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.8748 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -119.73, 172.45 | APE9-dihe-na | -57.82, 154.07 | APE8-dihe-in | -57.67, 128.89 | APE8-rot-in | 312.99 | APE67-dihe-in | -54.7, -25.18 | -56.78, -40.06 | APE12-dist-in | 10.0108 | APE11-dist-out | 6.4037 | APE10-dist-out | 8.6995 | APE9-dist-in | 3.4316 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | Q | 305.0 | 293.0 | 6 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | 3MY0R | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.3012 | 13.866 | BLAminus | -126.25, 177.57 | 66.35, 80.92 | -95.42, 16.6 | 279.94, 59.95 | -60.34, -24.6 | in-out | in | 8.7912 | Saltbr-out | 4.5972 | HRD-in | -70.63, -58.52 | 80.1, -2.42 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9285 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -120.04, 171.5 | APE9-dihe-na | -55.22, 155.39 | APE8-dihe-in | -60.94, 129.38 | APE8-rot-in | 309.71 | APE67-dihe-in | -61.16, -28.37 | -56.67, -32.79 | APE12-dist-in | 10.9941 | APE11-dist-out | 7.3002 | APE10-dist-out | 9.3736 | APE9-dist-in | 3.8766 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | R | 305.0 | 293.0 | 6 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | 3MY0S | P37023 | 195 | 492 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2509 | 13.8139 | BLAminus | -126.76, 175.46 | 68.14, 78.52 | -91.77, 12.89 | 280.08, 60.38 | -55.72, -27.45 | in-out | in | 8.7962 | Saltbr-out | 4.4097 | HRD-in | -73.17, -55.93 | 78.58, -3.85 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9478 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -124.96, 175.8 | APE9-dihe-na | -59.83, 158.33 | APE8-dihe-in | -59.62, 120.89 | APE8-rot-in | 305.6 | APE67-dihe-in | -56.3, -26.37 | -54.54, -40.41 | APE12-dist-in | 10.517 | APE11-dist-out | 6.6846 | APE10-dist-out | 8.9836 | APE9-dist-in | 3.8566 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | S | 305.0 | 293.0 | 5 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | 3MY0T | P37023 | 195 | 492 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2659 | 13.8346 | BLAminus | -124.05, 174.81 | 67.68, 81.32 | -94.08, 15.62 | 279.92, 60.16 | -61.29, -23.29 | in-out | in | 8.7725 | Saltbr-out | 4.6503 | HRD-in | -72.51, -55.56 | 77.51, -3.87 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.8632 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -117.94, 172.03 | APE9-dihe-na | -54.78, 156.93 | APE8-dihe-in | -61.35, 128.86 | APE8-rot-in | 308.81 | APE67-dihe-in | -60.23, -27.6 | -58.39, -36.33 | APE12-dist-in | 10.4057 | APE11-dist-out | 6.7108 | APE10-dist-out | 9.0677 | APE9-dist-in | 3.6938 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | T | 305.0 | 291.0 | 7 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | 3MY0U | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.248 | 13.8125 | BLAminus | -127.09, 176.86 | 65.6, 81.97 | -94.06, 14.89 | 280.32, 62.12 | -59.61, -25.26 | in-out | in | 8.8033 | Saltbr-out | 4.6535 | HRD-in | -71.88, -59.09 | 81.8, -4.45 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.8903 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -117.2, 171.51 | APE9-dihe-na | -53.69, 152.79 | APE8-dihe-in | -58.42, 128.6 | APE8-rot-in | 309.02 | APE67-dihe-in | -54.1, -28.78 | -59.57, -40.46 | APE12-dist-in | 10.288 | APE11-dist-out | 6.5638 | APE10-dist-out | 8.8641 | APE9-dist-in | 3.4658 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | U | 305.0 | 284.0 | 15 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | 3MY0V | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2762 | 13.8431 | BLAminus | -128.6, 175.3 | 67.4, 81.81 | -94.46, 15.31 | 279.41, 61.51 | -58.74, -25.89 | in-out | in | 8.7706 | Saltbr-out | 4.5612 | HRD-in | -72.01, -55.11 | 78.13, -5.36 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.8793 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -106.33, 170.13 | APE9-dihe-na | -53.24, 142.88 | APE8-dihe-in | -48.95, 122.15 | APE8-rot-in | 301.77 | APE67-dihe-in | -58.65, -23.08 | -65.1, -32.07 | APE12-dist-in | 10.4088 | APE11-dist-out | 6.5276 | APE10-dist-out | 9.0453 | APE9-dist-in | 3.7305 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | V | 305.0 | 281.0 | 18 | 32 | 24 | 8 | [[200, 491]] | 1.0 | 3my0 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | 3MY0W | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.3028 | 13.8516 | BLAminus | -125.85, 178.19 | 63.85, 80.77 | -94.37, 16.63 | 279.65, 61.82 | -60.97, -22.79 | in-out | in | 8.7904 | Saltbr-out | 4.5243 | HRD-in | -74.51, -54.41 | 76.72, -2.89 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.8986 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -118.48, 172.52 | APE9-dihe-na | -54.59, 156.92 | APE8-dihe-in | -60.16, 129.69 | APE8-rot-in | 308.24 | APE67-dihe-in | -59.51, -24.45 | -59.13, -39.59 | APE12-dist-in | 10.6045 | APE11-dist-out | 6.9679 | APE10-dist-out | 9.2094 | APE9-dist-in | 3.7227 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | W | 305.0 | 280.0 | 19 | 32 | 24 | 8 | [[200, 491]] | 1.0 | 3my0 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | 3MY0X | P37023 | 195 | 488 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2707 | 13.8255 | BLAminus | -126.44, 177.21 | 65.63, 81.13 | -94.67, 16.92 | 280.6, 61.06 | -60.39, -25.37 | in-out | in | 8.7738 | Saltbr-out | 4.597 | HRD-in | -72.12, -55.91 | 77.54, -2.81 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.8662 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -118.59, 172.83 | APE9-dihe-na | -54.96, 155.79 | APE8-dihe-in | -60.73, 129.46 | APE8-rot-in | 308.13 | APE67-dihe-in | -61.04, -27.19 | -59.1, -37.5 | APE12-dist-in | 10.7652 | APE11-dist-out | 6.8737 | APE10-dist-out | 9.1954 | APE9-dist-in | 3.755 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | X | 305.0 | 257.0 | 40 | 32 | 21 | 11 | [[200, 491]] | 1.0 | 3my0 | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACVRL1 | ACVL1_HUMAN | AF-P37023-K1A | P37023 | 194 | 499 | 503.0 | No_ligand | No_ligand | Active | DFGin | 6.6371 | 13.2251 | BLAminus | -125.9, 178.53 | 55.6, 69.32 | -87.18, 13.23 | 299.46, 176.29 | -63.45, -18.11 | in-in | in | 8.1981 | Saltbr-in | 2.7085 | HRD-in | -74.51, -40.12 | 65.67, -18.23 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8707 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -121.73, 170.02 | APE9-dihe-na | 100.1, -179.36 | APE8-dihe-in | -79.37, 114.79 | APE8-rot-in | 305.67 | APE67-dihe-in | -60.55, -25.81 | -44.92, -42.66 | APE12-dist-in | 11.284 | APE11-dist-in | 12.0229 | APE10-dist-in | 6.1844 | APE9-dist-in | 3.8991 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 306.0 | 306.0 | 0 | 32 | 32 | 0 | [[200, 491]] | 1.0 | AF-P37023-K1 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | AF-P37023-K3A | P37023 | 194 | 499 | 503.0 | No_ligand | No_ligand | Active | DFGin | 6.5567 | 13.1446 | BLAminus | -126.65, -177.52 | 56.86, 49.0 | -73.45, 1.99 | 298.85, 178.6 | -60.09, -18.55 | in-in | in | 7.9868 | Saltbr-in | 2.7023 | HRD-in | -76.48, -38.56 | 65.65, -26.13 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8062 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -114.75, 161.78 | APE9-dihe-na | 118.2, 172.43 | APE8-dihe-in | -85.98, 116.23 | APE8-rot-in | 302.25 | APE67-dihe-in | -63.07, -19.36 | -41.14, -46.72 | APE12-dist-in | 10.715 | APE11-dist-in | 11.2332 | APE10-dist-in | 5.4576 | APE9-dist-in | 3.8094 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 306.0 | 306.0 | 0 | 32 | 32 | 0 | [[200, 491]] | 1.0 | AF-P37023-K3 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | 3MY0A | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2559 | 13.8168 | BLAminus | -125.41, 179.58 | 64.23, 80.18 | -93.04, 16.17 | 280.44, 59.18 | -60.43, -25.79 | in-out | in | 8.8089 | Saltbr-out | 4.6541 | HRD-in | -75.03, -54.04 | 76.35, -2.61 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.8978 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -118.09, 170.06 | APE9-dihe-na | -54.91, 151.81 | APE8-dihe-in | -58.19, 127.96 | APE8-rot-in | 308.6 | APE67-dihe-in | -54.84, -26.12 | -60.37, -41.45 | APE12-dist-in | 10.7017 | APE11-dist-out | 6.8562 | APE10-dist-out | 9.1652 | APE9-dist-in | 3.59 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | A | 305.0 | 295.0 | 4 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | 3MY0B | P37023 | 195 | 494 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.282 | 13.8378 | BLAminus | -125.5, 176.91 | 65.33, 80.72 | -94.34, 16.94 | 280.76, 60.24 | -60.74, -22.47 | in-out | in | 8.7908 | Saltbr-out | 4.6638 | HRD-in | -70.36, -57.83 | 78.84, -3.15 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9084 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -118.81, 172.96 | APE9-dihe-na | -55.33, 155.22 | APE8-dihe-in | -58.33, 129.61 | APE8-rot-in | 310.35 | APE67-dihe-in | -57.43, -24.18 | -60.83, -40.24 | APE12-dist-in | 10.8595 | APE11-dist-out | 7.0191 | APE10-dist-out | 9.2706 | APE9-dist-in | 3.7536 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | B | 305.0 | 295.0 | 5 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | 3MY0C | P37023 | 195 | 492 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2906 | 13.8525 | BLAminus | -125.28, 179.94 | 63.19, 82.04 | -96.22, 18.21 | 279.16, 60.64 | -59.55, -26.97 | in-out | in | 8.7777 | Saltbr-out | 4.4878 | HRD-in | -74.47, -54.77 | 76.15, -2.86 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9644 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -127.27, 173.58 | APE9-dihe-na | -58.8, 157.05 | APE8-dihe-in | -60.34, 122.64 | APE8-rot-in | 302.84 | APE67-dihe-in | -56.55, -26.73 | -54.35, -41.84 | APE12-dist-in | 10.3375 | APE11-dist-out | 6.6753 | APE10-dist-out | 8.8911 | APE9-dist-in | 3.7201 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | C | 305.0 | 298.0 | 0 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | 3MY0D | P37023 | 195 | 491 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2484 | 13.8247 | BLAminus | -124.95, 176.57 | 67.57, 82.38 | -95.52, 17.16 | 280.1, 61.89 | -61.6, -24.06 | in-out | in | 8.775 | Saltbr-out | 4.6481 | HRD-in | -73.21, -54.97 | 76.6, -0.66 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9806 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -125.66, 176.14 | APE9-dihe-na | -59.34, 158.81 | APE8-dihe-in | -61.41, 119.86 | APE8-rot-in | 302.71 | APE67-dihe-in | -53.75, -26.66 | -53.87, -42.29 | APE12-dist-in | 10.4503 | APE11-dist-out | 6.5982 | APE10-dist-out | 8.884 | APE9-dist-in | 3.6726 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | D | 305.0 | 297.0 | 0 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | 3MY0E | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2731 | 13.8294 | BLAminus | -126.51, 175.94 | 66.5, 79.46 | -94.66, 19.24 | 281.15, 60.34 | -60.84, -27.1 | in-out | in | 8.7803 | Saltbr-out | 4.5178 | HRD-in | -75.02, -53.91 | 76.92, -5.86 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9223 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -120.98, 170.65 | APE9-dihe-na | -54.41, 156.64 | APE8-dihe-in | -61.09, 130.67 | APE8-rot-in | 310.34 | APE67-dihe-in | -58.81, -25.77 | -58.5, -39.08 | APE12-dist-in | 10.928 | APE11-dist-out | 7.0909 | APE10-dist-out | 9.3099 | APE9-dist-in | 3.7904 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | E | 305.0 | 293.0 | 6 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | 3MY0F | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.3087 | 13.8419 | BLAminus | -125.61, 177.33 | 65.02, 84.05 | -97.9, 17.92 | 280.6, 59.22 | -59.08, -26.58 | in-out | in | 8.7809 | Saltbr-out | 4.6093 | HRD-in | -73.07, -56.83 | 77.8, -3.03 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9034 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -119.08, 173.21 | APE9-dihe-na | -57.72, 152.44 | APE8-dihe-in | -56.61, 129.17 | APE8-rot-in | 309.69 | APE67-dihe-in | -57.05, -27.53 | -60.31, -37.52 | APE12-dist-in | 9.9689 | APE11-dist-out | 6.4883 | APE10-dist-out | 8.7085 | APE9-dist-in | 3.4413 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | F | 305.0 | 293.0 | 6 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | 3MY0G | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.3062 | 13.8266 | BLAminus | -125.88, 178.86 | 65.59, 83.12 | -96.91, 17.15 | 278.99, 62.26 | -59.85, -26.27 | in-out | in | 8.7684 | Saltbr-out | 4.5724 | HRD-in | -71.05, -57.49 | 79.48, -2.73 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9045 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -119.13, 171.83 | APE9-dihe-na | -53.51, 156.9 | APE8-dihe-in | -60.69, 129.01 | APE8-rot-in | 313.4 | APE67-dihe-in | -55.21, -26.28 | -57.22, -40.58 | APE12-dist-in | 10.6441 | APE11-dist-out | 6.9623 | APE10-dist-out | 9.1789 | APE9-dist-in | 3.6981 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | G | 305.0 | 293.0 | 6 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | 3MY0H | P37023 | 195 | 492 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2793 | 13.8772 | BLAminus | -127.12, 175.15 | 67.39, 80.98 | -93.48, 16.98 | 280.44, 59.29 | -58.69, -25.99 | in-out | in | 8.8145 | Saltbr-out | 4.6188 | HRD-in | -73.23, -54.57 | 76.21, -2.71 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.8992 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -126.72, 171.23 | APE9-dihe-na | -56.88, 158.03 | APE8-dihe-in | -60.18, 123.4 | APE8-rot-in | 306.72 | APE67-dihe-in | -54.25, -24.74 | -55.41, -42.39 | APE12-dist-in | 10.4908 | APE11-dist-out | 6.7371 | APE10-dist-out | 8.896 | APE9-dist-in | 3.7941 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | H | 305.0 | 293.0 | 5 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | 3MY0I | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.299 | 13.8413 | BLAminus | -127.43, 177.75 | 64.38, 81.53 | -95.75, 18.19 | 279.47, 62.86 | -61.72, -24.11 | in-out | in | 8.8069 | Saltbr-out | 4.6533 | HRD-in | -70.96, -57.86 | 78.33, -0.93 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.8478 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -117.48, 172.9 | APE9-dihe-na | -54.6, 153.3 | APE8-dihe-in | -58.52, 129.27 | APE8-rot-in | 311.22 | APE67-dihe-in | -54.61, -26.28 | -60.94, -38.76 | APE12-dist-in | 10.4833 | APE11-dist-out | 6.7406 | APE10-dist-out | 8.9697 | APE9-dist-in | 3.4815 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | I | 305.0 | 292.0 | 7 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | 3MY0J | P37023 | 200 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2755 | 13.8404 | BLAminus | -127.36, 177.46 | 65.38, 81.12 | -94.87, 16.49 | 280.58, 61.3 | -59.74, -24.71 | in-out | in | 8.786 | Saltbr-out | 4.5936 | HRD-in | -72.33, -56.82 | 78.64, -2.73 | out-in-none | SNCoin | in-none | ActLoopNT-in | 2.9157 | ActLoopCT-none | nonTYR | APEdihe_aannn | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 999.0 | APE8-rot-none | 999.0 | APE67-dihe-none | 999.0, -27.97 | 999.0, 999.0 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | J | 305.0 | 252.0 | 42 | 32 | 12 | 20 | [[200, 491]] | 1.0 | 3my0 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | 3MY0K | P37023 | 195 | 492 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2815 | 13.8283 | BLAminus | -128.06, 176.75 | 65.43, 82.77 | -95.72, 16.46 | 281.05, 60.32 | -60.13, -25.23 | in-out | in | 8.7674 | Saltbr-out | 4.5992 | HRD-in | -72.66, -56.49 | 79.37, -3.81 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9204 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -117.86, 173.18 | APE9-dihe-na | -55.66, 154.25 | APE8-dihe-in | -59.56, 129.15 | APE8-rot-in | 308.9 | APE67-dihe-in | -60.72, -26.44 | -60.12, -41.3 | APE12-dist-in | 10.0058 | APE11-dist-out | 6.0181 | APE10-dist-out | 9.0788 | APE9-dist-in | 3.5094 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | K | 305.0 | 261.0 | 37 | 32 | 23 | 9 | [[200, 491]] | 1.0 | 3my0 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | 3MY0L | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2573 | 13.8445 | BLAminus | -127.8, 177.54 | 64.87, 80.43 | -93.78, 16.91 | 280.46, 60.74 | -60.32, -23.66 | in-out | in | 8.8101 | Saltbr-out | 4.5353 | HRD-in | -74.09, -56.52 | 78.77, -3.63 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.882 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -119.49, 172.18 | APE9-dihe-na | -52.86, 155.13 | APE8-dihe-in | -61.31, 128.43 | APE8-rot-in | 309.91 | APE67-dihe-in | -61.26, -26.28 | -57.4, -34.74 | APE12-dist-in | 10.5176 | APE11-dist-out | 6.9861 | APE10-dist-out | 9.0891 | APE9-dist-in | 3.8055 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | L | 305.0 | 295.0 | 4 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | 3MY0M | P37023 | 195 | 494 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.3078 | 13.8516 | BLAminus | -124.52, 176.18 | 66.21, 82.42 | -94.8, 15.37 | 280.18, 60.8 | -60.1, -22.59 | in-out | in | 8.7838 | Saltbr-out | 4.5811 | HRD-in | -74.74, -52.47 | 77.56, -4.84 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9251 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -118.36, 173.56 | APE9-dihe-na | -55.01, 156.87 | APE8-dihe-in | -59.73, 130.8 | APE8-rot-in | 309.42 | APE67-dihe-in | -53.12, -26.51 | -60.99, -39.7 | APE12-dist-in | 10.5972 | APE11-dist-out | 6.9008 | APE10-dist-out | 9.0514 | APE9-dist-in | 3.5862 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | M | 305.0 | 297.0 | 3 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | 3MY0N | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2677 | 13.8495 | BLAminus | -125.99, 176.35 | 64.32, 84.23 | -94.91, 15.92 | 278.24, 61.08 | -58.16, -28.3 | in-out | in | 8.8005 | Saltbr-out | 4.5539 | HRD-in | -76.2, -55.28 | 77.66, -3.01 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9687 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -126.77, 175.42 | APE9-dihe-na | -61.21, 157.6 | APE8-dihe-in | -60.19, 120.19 | APE8-rot-in | 304.5 | APE67-dihe-in | -55.16, -25.15 | -51.9, -42.07 | APE12-dist-in | 10.4066 | APE11-dist-out | 6.6664 | APE10-dist-out | 8.9779 | APE9-dist-in | 3.7119 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | N | 305.0 | 299.0 | 0 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | 3MY0O | P37023 | 195 | 490 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2446 | 13.8256 | BLAminus | -124.42, 177.92 | 63.77, 82.48 | -95.09, 16.7 | 280.92, 59.16 | -59.26, -25.66 | in-out | in | 8.7688 | Saltbr-out | 4.6292 | HRD-in | -72.59, -55.78 | 77.27, -1.86 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9566 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -124.59, 174.26 | APE9-dihe-na | -59.01, 155.79 | APE8-dihe-in | -58.46, 122.31 | APE8-rot-in | 303.34 | APE67-dihe-in | -56.92, -30.83 | -54.23, -39.39 | APE12-dist-in | 10.5849 | APE11-dist-out | 6.8696 | APE10-dist-out | 9.1142 | APE9-dist-in | 3.8729 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | O | 305.0 | 296.0 | 1 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | 3MY0P | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2781 | 13.8312 | BLAminus | -126.85, 176.63 | 66.27, 80.08 | -94.49, 17.72 | 281.11, 60.29 | -59.62, -26.74 | in-out | in | 8.7787 | Saltbr-out | 4.604 | HRD-in | -73.25, -56.52 | 77.99, -3.26 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9979 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -153.25, 165.67 | APE9-dihe-na | -62.04, 116.18 | APE8-dihe-in | -38.19, 117.05 | APE8-rot-in | 315.84 | APE67-dihe-in | -54.95, -25.14 | -4.8, -73.53 | APE12-dist-in | 10.4624 | APE11-dist-out | 7.286 | APE10-dist-out | 8.3619 | APE9-dist-in | 3.0952 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | P | 305.0 | 290.0 | 9 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | 3MY0Q | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.3071 | 13.8327 | BLAminus | -126.7, 177.0 | 66.0, 82.27 | -96.39, 17.62 | 281.0, 60.69 | -60.74, -24.24 | in-out | in | 8.7826 | Saltbr-out | 4.5677 | HRD-in | -71.51, -56.19 | 77.55, -1.78 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.8748 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -119.73, 172.45 | APE9-dihe-na | -57.82, 154.07 | APE8-dihe-in | -57.67, 128.89 | APE8-rot-in | 312.99 | APE67-dihe-in | -54.7, -25.18 | -56.78, -40.06 | APE12-dist-in | 10.0108 | APE11-dist-out | 6.4037 | APE10-dist-out | 8.6995 | APE9-dist-in | 3.4316 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | Q | 305.0 | 293.0 | 6 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | 3MY0R | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.3012 | 13.866 | BLAminus | -126.25, 177.57 | 66.35, 80.92 | -95.42, 16.6 | 279.94, 59.95 | -60.34, -24.6 | in-out | in | 8.7912 | Saltbr-out | 4.5972 | HRD-in | -70.63, -58.52 | 80.1, -2.42 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9285 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -120.04, 171.5 | APE9-dihe-na | -55.22, 155.39 | APE8-dihe-in | -60.94, 129.38 | APE8-rot-in | 309.71 | APE67-dihe-in | -61.16, -28.37 | -56.67, -32.79 | APE12-dist-in | 10.9941 | APE11-dist-out | 7.3002 | APE10-dist-out | 9.3736 | APE9-dist-in | 3.8766 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | R | 305.0 | 293.0 | 6 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | 3MY0S | P37023 | 195 | 492 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2509 | 13.8139 | BLAminus | -126.76, 175.46 | 68.14, 78.52 | -91.77, 12.89 | 280.08, 60.38 | -55.72, -27.45 | in-out | in | 8.7962 | Saltbr-out | 4.4097 | HRD-in | -73.17, -55.93 | 78.58, -3.85 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9478 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -124.96, 175.8 | APE9-dihe-na | -59.83, 158.33 | APE8-dihe-in | -59.62, 120.89 | APE8-rot-in | 305.6 | APE67-dihe-in | -56.3, -26.37 | -54.54, -40.41 | APE12-dist-in | 10.517 | APE11-dist-out | 6.6846 | APE10-dist-out | 8.9836 | APE9-dist-in | 3.8566 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | S | 305.0 | 293.0 | 5 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | 3MY0T | P37023 | 195 | 492 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2659 | 13.8346 | BLAminus | -124.05, 174.81 | 67.68, 81.32 | -94.08, 15.62 | 279.92, 60.16 | -61.29, -23.29 | in-out | in | 8.7725 | Saltbr-out | 4.6503 | HRD-in | -72.51, -55.56 | 77.51, -3.87 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.8632 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -117.94, 172.03 | APE9-dihe-na | -54.78, 156.93 | APE8-dihe-in | -61.35, 128.86 | APE8-rot-in | 308.81 | APE67-dihe-in | -60.23, -27.6 | -58.39, -36.33 | APE12-dist-in | 10.4057 | APE11-dist-out | 6.7108 | APE10-dist-out | 9.0677 | APE9-dist-in | 3.6938 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | T | 305.0 | 291.0 | 7 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | 3MY0U | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.248 | 13.8125 | BLAminus | -127.09, 176.86 | 65.6, 81.97 | -94.06, 14.89 | 280.32, 62.12 | -59.61, -25.26 | in-out | in | 8.8033 | Saltbr-out | 4.6535 | HRD-in | -71.88, -59.09 | 81.8, -4.45 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.8903 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -117.2, 171.51 | APE9-dihe-na | -53.69, 152.79 | APE8-dihe-in | -58.42, 128.6 | APE8-rot-in | 309.02 | APE67-dihe-in | -54.1, -28.78 | -59.57, -40.46 | APE12-dist-in | 10.288 | APE11-dist-out | 6.5638 | APE10-dist-out | 8.8641 | APE9-dist-in | 3.4658 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | U | 305.0 | 284.0 | 15 | 32 | 32 | 0 | [[200, 491]] | 1.0 | 3my0 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | 3MY0V | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2762 | 13.8431 | BLAminus | -128.6, 175.3 | 67.4, 81.81 | -94.46, 15.31 | 279.41, 61.51 | -58.74, -25.89 | in-out | in | 8.7706 | Saltbr-out | 4.5612 | HRD-in | -72.01, -55.11 | 78.13, -5.36 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.8793 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -106.33, 170.13 | APE9-dihe-na | -53.24, 142.88 | APE8-dihe-in | -48.95, 122.15 | APE8-rot-in | 301.77 | APE67-dihe-in | -58.65, -23.08 | -65.1, -32.07 | APE12-dist-in | 10.4088 | APE11-dist-out | 6.5276 | APE10-dist-out | 9.0453 | APE9-dist-in | 3.7305 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | V | 305.0 | 281.0 | 18 | 32 | 24 | 8 | [[200, 491]] | 1.0 | 3my0 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | 3MY0W | P37023 | 195 | 493 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.3028 | 13.8516 | BLAminus | -125.85, 178.19 | 63.85, 80.77 | -94.37, 16.63 | 279.65, 61.82 | -60.97, -22.79 | in-out | in | 8.7904 | Saltbr-out | 4.5243 | HRD-in | -74.51, -54.41 | 76.72, -2.89 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.8986 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -118.48, 172.52 | APE9-dihe-na | -54.59, 156.92 | APE8-dihe-in | -60.16, 129.69 | APE8-rot-in | 308.24 | APE67-dihe-in | -59.51, -24.45 | -59.13, -39.59 | APE12-dist-in | 10.6045 | APE11-dist-out | 6.9679 | APE10-dist-out | 9.2094 | APE9-dist-in | 3.7227 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | W | 305.0 | 280.0 | 19 | 32 | 24 | 8 | [[200, 491]] | 1.0 | 3my0 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| ACVRL1 | ACVL1_HUMAN | 3MY0X | P37023 | 195 | 488 | 503.0 | LDN:60600 | Type1 | Inactive | DFGin | 7.2707 | 13.8255 | BLAminus | -126.44, 177.21 | 65.63, 81.13 | -94.67, 16.92 | 280.6, 61.06 | -60.39, -25.37 | in-out | in | 8.7738 | Saltbr-out | 4.597 | HRD-in | -72.12, -55.91 | 77.54, -2.81 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.8662 | ActLoopCT-out | nonTYR | APEdihe_aaiii | APEdist_iooi | APE10-dihe-na | -118.59, 172.83 | APE9-dihe-na | -54.96, 155.79 | APE8-dihe-in | -60.73, 129.46 | APE8-rot-in | 308.13 | APE67-dihe-in | -61.04, -27.19 | -59.1, -37.5 | APE12-dist-in | 10.7652 | APE11-dist-out | 6.8737 | APE10-dist-out | 9.1954 | APE9-dist-in | 3.755 | None | None | None | XRAY | 2.65 | 0.209 | 0.247 | X | 305.0 | 257.0 | 40 | 32 | 21 | 11 | [[200, 491]] | 1.0 | 3my0 | Homo sapiens | TKL_ACVRL1_HUMAN | TKL | 1.3e-81 | 280.0 | 3.0 | 267.0 | 265.0 | 347 | 348 | 349 | 351 | 353 | 229 | 242 | 246 | 327 | 329 | 328 | 330.0 | 397 | 379 | 374 | 373 | 372 | 371 | 370 | 369 | 368 | 278 | Activin receptor type-1-like |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|