TKL_ACVR1B (Activin receptor type-1B)

Total number of chains: 2
Active chains: 2
Family: TKL
Uniprot: ACV1B_HUMAN
Kinase Domain Residues: 207 - 496
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P36896-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

PDB First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AF-P36896-K1A 199 504 505.0 No_ligand No_ligand Active DFGin 6.555 13.278 BLAminus DFGAsp-rot-in -125.56, -179.71 55.95, 61.08 196.46, 36.38 -79.07, 16.21 297.39, 177.52 -63.48, -22.16 in-in in 8.275 Saltbr-in 2.691 HRD-in -73.75, -41.39 66.16, -21.43 in-in-in SNCiii in-in ActLoopNT-in 2.891 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -119.03, 165.84 APE9-dihe-na 99.77, -177.87 APE8-dihe-in -82.38, 116.18 APE8-rot-in 304.57 APE67-dihe-in -61.23, -24.86 -48.72, -40.74 APE12-dist-in 11.711 APE11-dist-in 12.037 APE10-dist-in 6.101 APE9-dist-in 3.987 None None None AF2 -1.0 1.0 1.0 A 306 306 0 0 0 0 [[207, 496]] 1.0 AF-P36896-K1 TKL_ACVR1B_HUMAN TKL 9.5e-82 280.4 3 266 264 352 353 354 356 358 234 247 251 332 334 333 335 402 384 379 378 377 376 375 374 373 283 Activin receptor type-1B
AF-P36896-K3A 199 504 505.0 No_ligand No_ligand Active DFGin 6.284 12.964 BLAminus DFGAsp-rot-in -130.0801, -179.6042 58.9997, 52.0502 199.6041, 23.7405 -74.061, 6.2323 301.9584, 0.6108 -63.3673, -19.1708 in-in in 8.072 Saltbr-in 2.674 HRD-in -74.5498, -40.3363 64.8294, -16.567 in-in-in SNCiii in-in ActLoopNT-in 2.844 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -118.3894, 156.7613 APE9-dihe-na 108.5027, -177.2453 APE8-dihe-in -96.0637, 115.0092 APE8-rot-in 302.1943 APE67-dihe-in -60.676, -26.2159 -38.9601, -48.8765 APE12-dist-in 11.342 APE11-dist-in 11.728 APE10-dist-in 5.802 APE9-dist-in 3.631 None None None AF2 -1.0 1.0 1.0 A 306 306 0 0 0 0 [[207, 496]] 1.0 AF-P36896-K3 TKL_ACVR1B_HUMAN TKL 9.5e-82 280.4 3 266 264 352 353 354 356 358 234 247 251 332 334 333 335 402 384 379 378 377 376 375 374 373 283 Activin receptor type-1B

TKL_ACVR1B (Activin receptor type-1B)

Total number of chains: 2
Active chains: 2
Family: TKL
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P36896-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
ACV1B_HUMAN AF-P36896-K1A P36896 199 504 505.0 No_ligand No_ligand Active DFGin 6.555 13.278 BLAminus DFGAsp-rot-in -125.56, -179.71 55.95, 61.08 196.46, 36.38 -79.07, 16.21 297.39, 177.52 -63.48, -22.16 in-in in 8.275 Saltbr-in 2.691 HRD-in -73.75, -41.39 66.16, -21.43 in-in-in SNCiii in-in ActLoopNT-in 2.891 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -119.03, 165.84 APE9-dihe-na 99.77, -177.87 APE8-dihe-in -82.38, 116.18 APE8-rot-in 304.57 APE67-dihe-in -61.23, -24.86 -48.72, -40.74 APE12-dist-in 11.711 APE11-dist-in 12.037 APE10-dist-in 6.101 APE9-dist-in 3.987 None None None AF2 -1.0 1.0 1.0 A 306 306 0 0 0 0 [[207, 496]] 1.0 AF-P36896-K1 Homo sapiens TKL_ACVR1B_HUMAN TKL 9.5e-82 280.4 3 266 264 352 353 354 356 358 234 247 251 332 334 333 335 402 384 379 378 377 376 375 374 373 283 Activin receptor type-1B
ACV1B_HUMAN AF-P36896-K3A P36896 199 504 505.0 No_ligand No_ligand Active DFGin 6.284 12.964 BLAminus DFGAsp-rot-in -130.0801, -179.6042 58.9997, 52.0502 199.6041, 23.7405 -74.061, 6.2323 301.9584, 0.6108 -63.3673, -19.1708 in-in in 8.072 Saltbr-in 2.674 HRD-in -74.5498, -40.3363 64.8294, -16.567 in-in-in SNCiii in-in ActLoopNT-in 2.844 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -118.3894, 156.7613 APE9-dihe-na 108.5027, -177.2453 APE8-dihe-in -96.0637, 115.0092 APE8-rot-in 302.1943 APE67-dihe-in -60.676, -26.2159 -38.9601, -48.8765 APE12-dist-in 11.342 APE11-dist-in 11.728 APE10-dist-in 5.802 APE9-dist-in 3.631 None None None AF2 -1.0 1.0 1.0 A 306 306 0 0 0 0 [[207, 496]] 1.0 AF-P36896-K3 Homo sapiens TKL_ACVR1B_HUMAN TKL 9.5e-82 280.4 3 266 264 352 353 354 356 358 234 247 251 332 334 333 335 402 384 379 378 377 376 375 374 373 283 Activin receptor type-1B

TKL_ACVR1B (Activin receptor type-1B)

Total number of chains: 0
Active chains: 0
Family: TKL
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name