Group	GeneDomain	SwissprotID	UniprotID	pdbchain	First_obs_res	Last_obs_res	Length_Unp	Ligand	Ligand_type	Activity_label	Spatial_label	Phe_Glu4_dis	Phe_Lys_dis	Dihedral_label	XDFG_Phi	XDFG_Psi	DFG_Phi	DFG_Psi	DFG_Chi1	DFG_Chi2	Phe_Phi	Phe_Psi	Phe_Chi1	Phe_Chi2	Gly_Phi	Gly_Psi	ChelixSaltbr_label	Chelix_label	Lys_Glu_dis	Saltbr_label	LysNZ_GluOE_dis	HRD_label	HRD_Phi	HRD_Psi	Arg_Phi	Arg_Psi	SNC_label	SNCpymol_label	ActLoop_label	ActLoopNT_label	DFG6_XHRD_dis	ActLoopCT_label	APEtype	APEdihe_label	APEdist_label	APE10_dihe_label	APE10_Phi	APE10_Psi	APE9_dihe_label	APE9_Phi	APE9_Psi	APE8_dihe_label	APE8_Phi	APE8_Psi	APE8_rot_label	APE8_Chi1	APE67_dihe_label	APE6_Phi	APE6_Psi	APE7_Phi	APE7_Psi	APE12_dist_label	APE12_DFG4_dis	APE11_dist_label	APE11_DFG4_dis	APE10_dist_label	APE10_DFG4_dis	APE9_dist_label	APE9_Arg_dis	Chain_mut	Chain_phos	Modified_aa	Method	Resolution	Rvalue	FreeRvalue	Chain_id	ChainLen	Ordered_residues	DisorderedResidues	ActLoopLength	ActLoopResolvedResidues	ActLoopDisorderedResidues	Kinase_domains_Unp	N_Kinase_domains_Unp	pdb	Species	Gene	Kincore_name	hmm	Evalue	Score	hmmbeg	hmmend	hmmlen	XDFGnum	DFGnum	PHEnum	DFG4num	DFG6num	LYSnum	GLUnum	GLU4num	XHRDnum	ARGnum	HRDnum	HRDaspnum	aFaspnum	APEnum	APE6num	APE7num	APE8num	APE9num	APE10num	APE11num	APE12num	Hinge1num	Protein_name
TKL	IRAK4	IRAK4_HUMAN	Q9NWZ3	9PSTA	165	458	460.0	A1CKQ:501	Type1	Inactive	DFGin	6.8574	13.7679	BLAminus	-138.0359	171.5917	69.3869	87.2165	209.2368	-24.4222	-108.5636	16.7306	309.8676	98.3732	-61.7394	-26.553	in-out	in	8.8627	Saltbr-out	3.7865	HRD-in	-74.4971	-50.1208	76.901	-0.4605	out-in-in	SNCoii	in-in	ActLoopNT-in	2.8311	ActLoopCT-in	nonTYR	APEdihe_aaiii	APEdist_iiii	APE10-dihe-na	-130.948	150.5444	APE9-dihe-na	145.5068	178.8652	APE8-dihe-in	-103.2439	119.5628	APE8-rot-in	311.4898	APE67-dihe-in	-58.6112	-16.1034	-56.05	-50.512	APE12-dist-in	10.137	APE11-dist-in	11.7755	APE10-dist-in	6.4124	APE9-dist-in	4.1343	None	TPO342,TPO345,SEP346	TPO342,TPO345,SEP346	XRAY	2.12	0.213	0.269	A	304.0	285.0	9	0	0	6	[[183, 456]]	1.0	9pst	Homo sapiens	IRAK4	TKL_IRAK4_HUMAN	TKL	4.3e-84	288.2	5.0	266.0	262.0	328	329	330	332	334	213	233	237	308	310	309	311.0	369	358	353	352	351	350	349	348	347	263	Interleukin-1 receptor-associated kinase 4
TKL	IRAK4	IRAK4_HUMAN	Q9NWZ3	9PSTB	164	458	460.0	A1CKQ:501	Type1	Inactive	DFGin	6.7976	13.6827	BLAminus	-138.8155	173.8615	68.1956	85.3014	198.9303	4.3794	-107.1576	24.7947	312.4238	95.7828	-64.3306	-25.9394	in-out	in	8.6831	Saltbr-out	5.2237	HRD-in	-74.102	-48.4642	75.4598	-2.3757	out-in-in	SNCoii	in-in	ActLoopNT-in	2.6362	ActLoopCT-in	nonTYR	APEdihe_aaiii	APEdist_iiii	APE10-dihe-na	-132.7719	147.8569	APE9-dihe-na	140.2127	-166.6404	APE8-dihe-in	-114.1453	109.5227	APE8-rot-in	307.0645	APE67-dihe-in	-58.8673	-16.2359	-41.7769	-53.2358	APE12-dist-in	10.2263	APE11-dist-in	12.1116	APE10-dist-in	6.8298	APE9-dist-in	4.3116	None	TPO342,TPO345,SEP346	TPO342,TPO345,SEP346	XRAY	2.12	0.213	0.269	B	304.0	282.0	13	0	0	5	[[183, 456]]	1.0	9pst	Homo sapiens	IRAK4	TKL_IRAK4_HUMAN	TKL	4.3e-84	288.2	5.0	266.0	262.0	328	329	330	332	334	213	233	237	308	310	309	311.0	369	358	353	352	351	350	349	348	347	263	Interleukin-1 receptor-associated kinase 4
TKL	IRAK4	IRAK4_HUMAN	Q9NWZ3	9PSTC	164	458	460.0	A1CKQ:501	Type1	Active	DFGin	7.0333	13.8484	BLAminus	-134.8883	169.8845	66.9153	82.7344	208.9699	-22.0804	-103.7096	21.2595	312.8154	95.2814	-57.5417	-31.9158	in-in	in	8.7825	Saltbr-in	3.3563	HRD-in	-68.3641	-55.0064	81.6372	-1.016	in-in-in	SNCiii	in-in	ActLoopNT-in	2.6287	ActLoopCT-in	nonTYR	APEdihe_aaiii	APEdist_iiii	APE10-dihe-na	-128.9944	161.8071	APE9-dihe-na	130.2025	178.888	APE8-dihe-in	-100.823	118.0674	APE8-rot-in	300.8392	APE67-dihe-in	-63.2008	-19.3607	-63.186	-37.5926	APE12-dist-in	10.1295	APE11-dist-in	11.8035	APE10-dist-in	6.458	APE9-dist-in	4.0377	None	TPO342,TPO345,SEP346	TPO342,TPO345,SEP346	XRAY	2.12	0.213	0.269	C	304.0	284.0	11	0	0	6	[[183, 456]]	1.0	9pst	Homo sapiens	IRAK4	TKL_IRAK4_HUMAN	TKL	4.3e-84	288.2	5.0	266.0	262.0	328	329	330	332	334	213	233	237	308	310	309	311.0	369	358	353	352	351	350	349	348	347	263	Interleukin-1 receptor-associated kinase 4
TKL	IRAK4	IRAK4_HUMAN	Q9NWZ3	9PSTD	164	458	460.0	A1CKQ:501	Type1	Inactive	DFGin	6.787	13.5463	BLAminus	-133.7297	171.7245	68.243	78.0593	210.863	-18.5566	-102.208	24.4954	315.8124	99.3934	-76.3624	-24.173	in-out	in	8.7777	Saltbr-out	4.7123	HRD-in	-73.7549	-49.212	77.4163	3.2895	out-in-in	SNCoii	in-in	ActLoopNT-in	2.761	ActLoopCT-in	nonTYR	APEdihe_aaiii	APEdist_iiii	APE10-dihe-na	-121.9864	147.2619	APE9-dihe-na	137.5219	-173.0658	APE8-dihe-in	-107.8843	117.1744	APE8-rot-in	309.5126	APE67-dihe-in	-65.8942	-13.6121	-52.0823	-46.4041	APE12-dist-in	10.3501	APE11-dist-in	12.0318	APE10-dist-in	6.4024	APE9-dist-in	4.0375	None	TPO342,TPO345,SEP346	TPO342,TPO345,SEP346	XRAY	2.12	0.213	0.269	D	304.0	282.0	13	0	0	4	[[183, 456]]	1.0	9pst	Homo sapiens	IRAK4	TKL_IRAK4_HUMAN	TKL	4.3e-84	288.2	5.0	266.0	262.0	328	329	330	332	334	213	233	237	308	310	309	311.0	369	358	353	352	351	350	349	348	347	263	Interleukin-1 receptor-associated kinase 4