PDB: AF-Q92630 — CMGC DYRK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q92630-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK2 DYRK2_HUMAN AF-Q92630-K1A Q92630 214 543 601.0 No_ligand No_ligand Active DFGin 6.9387 14.8642 BLAminus -126.07, 177.15 62.42, 65.44 -81.73, 10.25 284.63, 80.53 -64.64, -17.85 in-in in 8.7276 Saltbr-in 2.7234 HRD-in -66.96, -37.74 67.08, -16.77 in-in-in SNCiii in-in ActLoopNT-in 2.8481 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.84, 175.12 APE9-dihe-na 60.6, 144.79 APE8-dihe-in -65.13, 137.41 APE8-rot-in 294.19 APE67-dihe-in -65.52, -19.21 -50.69, -46.33 APE12-dist-in 12.8823 APE11-dist-in 11.3343 APE10-dist-in 7.2875 APE9-dist-in 3.0213 None None None AF2 -1.0 1.0 1.0 A 330.0 330.0 0 25 25 0 [[222, 535]] 1.0 AF-Q92630-K1 CMGC_DYRK2_HUMAN CMGC 5.8e-99 337.0 1.0 301.0 301.0 367 368 369 371 373 251 266 270 345 347 346 348.0 404 392 387 386 385 384 383 382 381 302 Dual specificity tyrosine-phosphorylation-regulated kinase 2
CMGC DYRK2 DYRK2_HUMAN AF-Q92630-K3A Q92630 214 543 601.0 No_ligand No_ligand Active DFGin 6.6226 14.4713 BLAminus -128.09, 177.13 63.4, 64.99 -80.7, 10.08 289.17, 77.94 -66.05, -16.49 in-in in 8.8393 Saltbr-in 2.7344 HRD-in -72.99, -34.76 62.62, -5.57 in-in-in SNCiii in-in ActLoopNT-in 2.8816 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.48, 175.5 APE9-dihe-na 61.64, 142.59 APE8-dihe-in -63.51, 134.37 APE8-rot-in 293.35 APE67-dihe-in -63.69, -20.47 -54.61, -45.06 APE12-dist-in 12.7962 APE11-dist-in 11.3413 APE10-dist-in 7.0304 APE9-dist-in 3.0904 None None None AF2 -1.0 1.0 1.0 A 330.0 330.0 0 25 25 0 [[222, 535]] 1.0 AF-Q92630-K3 CMGC_DYRK2_HUMAN CMGC 5.8e-99 337.0 1.0 301.0 301.0 367 368 369 371 373 251 266 270 345 347 346 348.0 404 392 387 386 385 384 383 382 381 302 Dual specificity tyrosine-phosphorylation-regulated kinase 2

PDB: AF-Q92630 — CMGC DYRK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q92630-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK2 DYRK2_HUMAN AF-Q92630-K1A Q92630 214 543 601.0 No_ligand No_ligand Active DFGin 6.9387 14.8642 BLAminus -126.07, 177.15 62.42, 65.44 -81.73, 10.25 284.63, 80.53 -64.64, -17.85 in-in in 8.7276 Saltbr-in 2.7234 HRD-in -66.96, -37.74 67.08, -16.77 in-in-in SNCiii in-in ActLoopNT-in 2.8481 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.84, 175.12 APE9-dihe-na 60.6, 144.79 APE8-dihe-in -65.13, 137.41 APE8-rot-in 294.19 APE67-dihe-in -65.52, -19.21 -50.69, -46.33 APE12-dist-in 12.8823 APE11-dist-in 11.3343 APE10-dist-in 7.2875 APE9-dist-in 3.0213 None None None AF2 -1.0 1.0 1.0 A 330.0 330.0 0 25 25 0 [[222, 535]] 1.0 AF-Q92630-K1 Homo sapiens CMGC_DYRK2_HUMAN CMGC 5.8e-99 337.0 1.0 301.0 301.0 367 368 369 371 373 251 266 270 345 347 346 348.0 404 392 387 386 385 384 383 382 381 302 Dual specificity tyrosine-phosphorylation-regulated kinase 2
CMGC DYRK2 DYRK2_HUMAN AF-Q92630-K3A Q92630 214 543 601.0 No_ligand No_ligand Active DFGin 6.6226 14.4713 BLAminus -128.09, 177.13 63.4, 64.99 -80.7, 10.08 289.17, 77.94 -66.05, -16.49 in-in in 8.8393 Saltbr-in 2.7344 HRD-in -72.99, -34.76 62.62, -5.57 in-in-in SNCiii in-in ActLoopNT-in 2.8816 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.48, 175.5 APE9-dihe-na 61.64, 142.59 APE8-dihe-in -63.51, 134.37 APE8-rot-in 293.35 APE67-dihe-in -63.69, -20.47 -54.61, -45.06 APE12-dist-in 12.7962 APE11-dist-in 11.3413 APE10-dist-in 7.0304 APE9-dist-in 3.0904 None None None AF2 -1.0 1.0 1.0 A 330.0 330.0 0 25 25 0 [[222, 535]] 1.0 AF-Q92630-K3 Homo sapiens CMGC_DYRK2_HUMAN CMGC 5.8e-99 337.0 1.0 301.0 301.0 367 368 369 371 373 251 266 270 345 347 346 348.0 404 392 387 386 385 384 383 382 381 302 Dual specificity tyrosine-phosphorylation-regulated kinase 2

PDB: AF-Q92630 — CMGC DYRK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name