PDB: AF-Q08881 — TYR ITK_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q08881-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR ITK ITK_HUMAN AF-Q08881-K1A Q08881 355 620 620.0 No_ligand No_ligand Active DFGin 6.8214 13.9075 BLAminus -136.24, -175.79 55.48, 69.15 -84.68, 14.38 297.44, 87.73 -59.11, -31.45 in-in in 8.5169 Saltbr-in 2.6683 HRD-in -76.35, -40.21 67.29, -20.01 in-in-in SNCiii in-in ActLoopNT-in 2.9949 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -76.3, 148.47 APE9-dihe-in -144.93, 156.29 APE8-dihe-in -75.22, 86.83 APE8-rot-na 32.7 APE67-dihe-in -68.82, -16.14 -43.59, -41.61 APE12-dist-na 14.8323 APE11-dist-na 9.9539 APE10-dist-na 11.6241 APE9-dist-in 6.7433 None None None AF2 -1.0 1.0 1.0 A 266.0 266.0 0 29 29 0 [[363, 614]] 1.0 AF-Q08881-K1 TYR_ITK_HUMAN TYR 9.4e-93 316.2 1.0 260.0 260.0 499 500 501 503 505 391 406 410 479 481 480 482.0 540 528 523 522 521 520 519 518 517 436 Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN AF-Q08881-K3A Q08881 355 620 620.0 No_ligand No_ligand Active DFGin 6.5024 13.9854 BLAminus -144.79, -174.87 55.86, 66.43 -79.5, 8.16 297.06, 87.75 -59.87, -25.16 in-in in 9.038 Saltbr-in 2.7194 HRD-in -79.2, -42.03 68.19, -14.89 in-in-in SNCiii in-in ActLoopNT-in 2.8904 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -70.4, 141.24 APE9-dihe-in -149.38, 158.97 APE8-dihe-in -78.23, 79.46 APE8-rot-na 37.36 APE67-dihe-in -71.52, -13.15 -44.16, -41.92 APE12-dist-na 13.8458 APE11-dist-na 9.0808 APE10-dist-na 9.903 APE9-dist-in 5.7563 None None None AF2 -1.0 1.0 1.0 A 266.0 266.0 0 29 29 0 [[363, 614]] 1.0 AF-Q08881-K3 TYR_ITK_HUMAN TYR 9.4e-93 316.2 1.0 260.0 260.0 499 500 501 503 505 391 406 410 479 481 480 482.0 540 528 523 522 521 520 519 518 517 436 Tyrosine-protein kinase ITK/TSK

PDB: AF-Q08881 — TYR ITK_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q08881-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR ITK ITK_HUMAN AF-Q08881-K1A Q08881 355 620 620.0 No_ligand No_ligand Active DFGin 6.8214 13.9075 BLAminus -136.24, -175.79 55.48, 69.15 -84.68, 14.38 297.44, 87.73 -59.11, -31.45 in-in in 8.5169 Saltbr-in 2.6683 HRD-in -76.35, -40.21 67.29, -20.01 in-in-in SNCiii in-in ActLoopNT-in 2.9949 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -76.3, 148.47 APE9-dihe-in -144.93, 156.29 APE8-dihe-in -75.22, 86.83 APE8-rot-na 32.7 APE67-dihe-in -68.82, -16.14 -43.59, -41.61 APE12-dist-na 14.8323 APE11-dist-na 9.9539 APE10-dist-na 11.6241 APE9-dist-in 6.7433 None None None AF2 -1.0 1.0 1.0 A 266.0 266.0 0 29 29 0 [[363, 614]] 1.0 AF-Q08881-K1 Homo sapiens TYR_ITK_HUMAN TYR 9.4e-93 316.2 1.0 260.0 260.0 499 500 501 503 505 391 406 410 479 481 480 482.0 540 528 523 522 521 520 519 518 517 436 Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN AF-Q08881-K3A Q08881 355 620 620.0 No_ligand No_ligand Active DFGin 6.5024 13.9854 BLAminus -144.79, -174.87 55.86, 66.43 -79.5, 8.16 297.06, 87.75 -59.87, -25.16 in-in in 9.038 Saltbr-in 2.7194 HRD-in -79.2, -42.03 68.19, -14.89 in-in-in SNCiii in-in ActLoopNT-in 2.8904 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -70.4, 141.24 APE9-dihe-in -149.38, 158.97 APE8-dihe-in -78.23, 79.46 APE8-rot-na 37.36 APE67-dihe-in -71.52, -13.15 -44.16, -41.92 APE12-dist-na 13.8458 APE11-dist-na 9.0808 APE10-dist-na 9.903 APE9-dist-in 5.7563 None None None AF2 -1.0 1.0 1.0 A 266.0 266.0 0 29 29 0 [[363, 614]] 1.0 AF-Q08881-K3 Homo sapiens TYR_ITK_HUMAN TYR 9.4e-93 316.2 1.0 260.0 260.0 499 500 501 503 505 391 406 410 479 481 480 482.0 540 528 523 522 521 520 519 518 517 436 Tyrosine-protein kinase ITK/TSK

PDB: AF-Q08881 — TYR ITK_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name