PDB: AF-P53778 — CMGC MK12_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P53778-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK12 MK12_HUMAN AF-P53778-K1A P53778 19 319 367.0 No_ligand No_ligand Active DFGin 6.942 14.5801 BLAminus -114.74, 171.49 59.55, 70.2 -81.36, 15.32 288.02, 85.0 -61.25, -29.33 in-in in 9.0711 Saltbr-in 2.6529 HRD-in -75.03, -49.4 63.95, 16.94 in-in-in SNCiii in-in ActLoopNT-in 2.887 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -111.53, 169.25 APE9-dihe-na 64.71, 138.58 APE8-dihe-in -57.41, 128.64 APE8-rot-in 298.8 APE67-dihe-in -69.45, -18.41 -45.26, -45.85 APE12-dist-in 11.2922 APE11-dist-in 11.3371 APE10-dist-in 6.9597 APE9-dist-in 3.1547 None None None AF2 -1.0 1.0 1.0 A 301.0 301.0 0 25 25 0 [[27, 311]] 1.0 AF-P53778-K1 CMGC_MAPK12_HUMAN CMGC 2.7e-85 292.1 1.0 301.0 301.0 170 171 172 174 176 56 74 78 150 152 151 153.0 208 195 190 189 188 187 186 185 184 110 Mitogen-activated protein kinase 12
CMGC MAPK12 MK12_HUMAN AF-P53778-K3A P53778 19 319 367.0 No_ligand No_ligand Active DFGin 6.6544 14.4129 BLAminus -117.05, 172.87 62.36, 62.32 -74.09, 13.82 287.94, 79.39 -62.76, -22.02 in-in in 9.4048 Saltbr-in 2.7182 HRD-in -73.87, -45.92 63.52, 15.65 in-in-in SNCiii in-in ActLoopNT-in 2.8434 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -83.66, 170.51 APE9-dihe-na 63.91, 132.83 APE8-dihe-in -56.22, 129.24 APE8-rot-in 295.98 APE67-dihe-in -70.87, -16.95 -43.53, -47.75 APE12-dist-in 10.9428 APE11-dist-in 10.8558 APE10-dist-in 6.5565 APE9-dist-in 3.1513 None None None AF2 -1.0 1.0 1.0 A 301.0 301.0 0 25 25 0 [[27, 311]] 1.0 AF-P53778-K3 CMGC_MAPK12_HUMAN CMGC 2.7e-85 292.1 1.0 301.0 301.0 170 171 172 174 176 56 74 78 150 152 151 153.0 208 195 190 189 188 187 186 185 184 110 Mitogen-activated protein kinase 12

PDB: AF-P53778 — CMGC MK12_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P53778-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK12 MK12_HUMAN AF-P53778-K1A P53778 19 319 367.0 No_ligand No_ligand Active DFGin 6.942 14.5801 BLAminus -114.74, 171.49 59.55, 70.2 -81.36, 15.32 288.02, 85.0 -61.25, -29.33 in-in in 9.0711 Saltbr-in 2.6529 HRD-in -75.03, -49.4 63.95, 16.94 in-in-in SNCiii in-in ActLoopNT-in 2.887 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -111.53, 169.25 APE9-dihe-na 64.71, 138.58 APE8-dihe-in -57.41, 128.64 APE8-rot-in 298.8 APE67-dihe-in -69.45, -18.41 -45.26, -45.85 APE12-dist-in 11.2922 APE11-dist-in 11.3371 APE10-dist-in 6.9597 APE9-dist-in 3.1547 None None None AF2 -1.0 1.0 1.0 A 301.0 301.0 0 25 25 0 [[27, 311]] 1.0 AF-P53778-K1 Homo sapiens CMGC_MAPK12_HUMAN CMGC 2.7e-85 292.1 1.0 301.0 301.0 170 171 172 174 176 56 74 78 150 152 151 153.0 208 195 190 189 188 187 186 185 184 110 Mitogen-activated protein kinase 12
CMGC MAPK12 MK12_HUMAN AF-P53778-K3A P53778 19 319 367.0 No_ligand No_ligand Active DFGin 6.6544 14.4129 BLAminus -117.05, 172.87 62.36, 62.32 -74.09, 13.82 287.94, 79.39 -62.76, -22.02 in-in in 9.4048 Saltbr-in 2.7182 HRD-in -73.87, -45.92 63.52, 15.65 in-in-in SNCiii in-in ActLoopNT-in 2.8434 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -83.66, 170.51 APE9-dihe-na 63.91, 132.83 APE8-dihe-in -56.22, 129.24 APE8-rot-in 295.98 APE67-dihe-in -70.87, -16.95 -43.53, -47.75 APE12-dist-in 10.9428 APE11-dist-in 10.8558 APE10-dist-in 6.5565 APE9-dist-in 3.1513 None None None AF2 -1.0 1.0 1.0 A 301.0 301.0 0 25 25 0 [[27, 311]] 1.0 AF-P53778-K3 Homo sapiens CMGC_MAPK12_HUMAN CMGC 2.7e-85 292.1 1.0 301.0 301.0 170 171 172 174 176 56 74 78 150 152 151 153.0 208 195 190 189 188 187 186 185 184 110 Mitogen-activated protein kinase 12

PDB: AF-P53778 — CMGC MK12_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name