PDB: AF-P52333 — TYR JAK3_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P52333-K2A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK3-2 JAK3_HUMAN AF-P52333-K2A P52333 814 1105 1124.0 No_ligand No_ligand Active DFGin 6.1026 13.7936 BLAminus -134.56, -179.19 51.31, 75.31 -82.94, 20.6 292.85, 86.33 -61.55, -30.97 in-in in 8.2483 Saltbr-in 2.6953 HRD-in -70.59, -43.72 65.57, -21.68 in-in-in SNCiii in-in ActLoopNT-in 2.8552 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -56.42, 123.08 APE9-dihe-in -125.57, 135.88 APE8-dihe-in -78.86, 68.83 APE8-rot-na 34.92 APE67-dihe-in -75.13, -6.36 -53.49, -31.1 APE12-dist-na 10.5223 APE11-dist-na 9.5286 APE10-dist-na 10.1849 APE9-dist-in 7.1879 None None None AF2 -1.0 1.0 1.0 A 292.0 292.0 0 31 31 0 [[521, 779], [822, 1097]] 2.0 AF-P52333-K2 TYR_JAK3-2_HUMAN TYR 4.6e-81 277.9 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN AF-P52333-K4A P52333 814 1105 1124.0 No_ligand No_ligand Active DFGin 6.1108 13.7687 BLAminus -141.5, -174.59 54.28, 75.11 -88.15, 17.45 293.92, 89.95 -59.55, -34.59 in-in in 8.1169 Saltbr-in 2.6779 HRD-in -78.79, -45.55 61.88, 0.83 in-in-in SNCiii in-in ActLoopNT-in 2.8819 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -61.64, 120.49 APE9-dihe-in -128.67, 141.65 APE8-dihe-in -77.57, 68.42 APE8-rot-na 36.41 APE67-dihe-in -72.34, -8.01 -50.71, -34.24 APE12-dist-na 13.4854 APE11-dist-na 9.5574 APE10-dist-na 10.1649 APE9-dist-in 6.4962 None None None AF2 -1.0 1.0 1.0 A 292.0 292.0 0 31 31 0 [[521, 779], [822, 1097]] 2.0 AF-P52333-K4 TYR_JAK3-2_HUMAN TYR 4.6e-81 277.9 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3

PDB: AF-P52333 — TYR JAK3_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P52333-K2A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK3-2 JAK3_HUMAN AF-P52333-K2A P52333 814 1105 1124.0 No_ligand No_ligand Active DFGin 6.1026 13.7936 BLAminus -134.56, -179.19 51.31, 75.31 -82.94, 20.6 292.85, 86.33 -61.55, -30.97 in-in in 8.2483 Saltbr-in 2.6953 HRD-in -70.59, -43.72 65.57, -21.68 in-in-in SNCiii in-in ActLoopNT-in 2.8552 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -56.42, 123.08 APE9-dihe-in -125.57, 135.88 APE8-dihe-in -78.86, 68.83 APE8-rot-na 34.92 APE67-dihe-in -75.13, -6.36 -53.49, -31.1 APE12-dist-na 10.5223 APE11-dist-na 9.5286 APE10-dist-na 10.1849 APE9-dist-in 7.1879 None None None AF2 -1.0 1.0 1.0 A 292.0 292.0 0 31 31 0 [[521, 779], [822, 1097]] 2.0 AF-P52333-K2 Homo sapiens TYR_JAK3-2_HUMAN TYR 4.6e-81 277.9 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN AF-P52333-K4A P52333 814 1105 1124.0 No_ligand No_ligand Active DFGin 6.1108 13.7687 BLAminus -141.5, -174.59 54.28, 75.11 -88.15, 17.45 293.92, 89.95 -59.55, -34.59 in-in in 8.1169 Saltbr-in 2.6779 HRD-in -78.79, -45.55 61.88, 0.83 in-in-in SNCiii in-in ActLoopNT-in 2.8819 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -61.64, 120.49 APE9-dihe-in -128.67, 141.65 APE8-dihe-in -77.57, 68.42 APE8-rot-na 36.41 APE67-dihe-in -72.34, -8.01 -50.71, -34.24 APE12-dist-na 13.4854 APE11-dist-na 9.5574 APE10-dist-na 10.1649 APE9-dist-in 6.4962 None None None AF2 -1.0 1.0 1.0 A 292.0 292.0 0 31 31 0 [[521, 779], [822, 1097]] 2.0 AF-P52333-K4 Homo sapiens TYR_JAK3-2_HUMAN TYR 4.6e-81 277.9 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3

PDB: AF-P52333 — TYR JAK3_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name