PDB: AF-P49760 — CMGC CLK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P49760-K1A
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CLK2 CLK2_HUMAN AF-P49760-K1A P49760 155 487 499.0 No_ligand No_ligand Active DFGin 7.017 14.447 BLAminus -126.22, 175.17 64.05, 67.73 -82.36, 10.77 293.87, 94.93 -66.07, -15.18 in-in in 8.629 Saltbr-in 2.737 HRD-in -71.37, -38.9 64.95, -17.31 in-in-in SNCiii in-in ActLoopNT-in 2.897 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.18, 175.15 APE9-dihe-na 65.62, 146.25 APE8-dihe-in -58.43, 137.37 APE8-rot-in 294.29 APE67-dihe-in -69.47, -18.12 -49.92, -45.23 APE12-dist-in 13.835 APE11-dist-in 11.808 APE10-dist-in 7.504 APE9-dist-in 2.937 None None None AF2 -1.0 1.0 1.0 A 333 333 0 0 0 0 [[163, 479]] 1.0 AF-P49760-K1 CMGC_CLK2_HUMAN CMGC 1.3e-92 316.2 1 301 301 326 327 328 330 332 193 208 212 287 289 288 290 363 351 346 345 344 343 342 341 340 244 Dual specificity protein kinase CLK2
CMGC CLK2 CLK2_HUMAN AF-P49760-K3A P49760 155 487 499.0 No_ligand No_ligand Active DFGin 6.641 14.358 BLAminus -127.7, 177.09 63.58, 64.12 -79.63, 11.17 297.99, 96.21 -65.88, -8.85 in-in in 8.47 Saltbr-in 2.689 HRD-in -74.26, -40.62 70.17, -26.03 in-in-in SNCiii in-in ActLoopNT-in 2.905 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.16, -178.79 APE9-dihe-na 64.17, 140.54 APE8-dihe-in -54.77, 136.12 APE8-rot-in 294.36 APE67-dihe-in -67.89, -21.3 -52.25, -41.65 APE12-dist-in 13.715 APE11-dist-in 11.759 APE10-dist-in 7.299 APE9-dist-in 2.982 None None None AF2 -1.0 1.0 1.0 A 333 333 0 0 0 0 [[163, 479]] 1.0 AF-P49760-K3 CMGC_CLK2_HUMAN CMGC 1.3e-92 316.2 1 301 301 326 327 328 330 332 193 208 212 287 289 288 290 363 351 346 345 344 343 342 341 340 244 Dual specificity protein kinase CLK2

PDB: AF-P49760 — CMGC CLK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P49760-K1A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CLK2 CLK2_HUMAN AF-P49760-K1A P49760 155 487 499.0 No_ligand No_ligand Active DFGin 7.017 14.447 BLAminus -126.22, 175.17 64.05, 67.73 -82.36, 10.77 293.87, 94.93 -66.07, -15.18 in-in in 8.629 Saltbr-in 2.737 HRD-in -71.37, -38.9 64.95, -17.31 in-in-in SNCiii in-in ActLoopNT-in 2.897 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.18, 175.15 APE9-dihe-na 65.62, 146.25 APE8-dihe-in -58.43, 137.37 APE8-rot-in 294.29 APE67-dihe-in -69.47, -18.12 -49.92, -45.23 APE12-dist-in 13.835 APE11-dist-in 11.808 APE10-dist-in 7.504 APE9-dist-in 2.937 None None None AF2 -1.0 1.0 1.0 A 333 333 0 0 0 0 [[163, 479]] 1.0 AF-P49760-K1 Homo sapiens CMGC_CLK2_HUMAN CMGC 1.3e-92 316.2 1 301 301 326 327 328 330 332 193 208 212 287 289 288 290 363 351 346 345 344 343 342 341 340 244 Dual specificity protein kinase CLK2
CMGC CLK2 CLK2_HUMAN AF-P49760-K3A P49760 155 487 499.0 No_ligand No_ligand Active DFGin 6.641 14.358 BLAminus -127.7, 177.09 63.58, 64.12 -79.63, 11.17 297.99, 96.21 -65.88, -8.85 in-in in 8.47 Saltbr-in 2.689 HRD-in -74.26, -40.62 70.17, -26.03 in-in-in SNCiii in-in ActLoopNT-in 2.905 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.16, -178.79 APE9-dihe-na 64.17, 140.54 APE8-dihe-in -54.77, 136.12 APE8-rot-in 294.36 APE67-dihe-in -67.89, -21.3 -52.25, -41.65 APE12-dist-in 13.715 APE11-dist-in 11.759 APE10-dist-in 7.299 APE9-dist-in 2.982 None None None AF2 -1.0 1.0 1.0 A 333 333 0 0 0 0 [[163, 479]] 1.0 AF-P49760-K3 Homo sapiens CMGC_CLK2_HUMAN CMGC 1.3e-92 316.2 1 301 301 326 327 328 330 332 193 208 212 287 289 288 290 363 351 346 345 344 343 342 341 340 244 Dual specificity protein kinase CLK2

PDB: AF-P49760 — CMGC CLK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name