PDB: AF-P45983 — CMGC MK08_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P45983-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK8 MK08_HUMAN AF-P45983-K1A P45983 18 329 427.0 No_ligand No_ligand Active DFGin 6.4146 13.6432 BLAminus -143.36, 178.91 71.76, 59.86 -79.25, 6.67 305.71, 110.21 -57.24, -28.48 in-in in 8.7613 Saltbr-in 2.7045 HRD-in -68.06, -45.26 66.86, -8.1 in-in-in SNCiii in-in ActLoopNT-in 2.7803 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -79.62, -32.38 APE9-dihe-na -74.54, 148.67 APE8-dihe-in -64.82, 122.89 APE8-rot-in 305.16 APE67-dihe-in -66.57, -21.46 -45.8, -48.81 APE12-dist-in 12.8637 APE11-dist-in 12.5239 APE10-dist-in 6.8143 APE9-dist-in 4.4072 None None None AF2 -1.0 1.0 1.0 A 312.0 312.0 0 27 27 0 [[26, 321]] 1.0 AF-P45983-K1 CMGC_MAPK8_HUMAN CMGC 2.4e-84 288.9 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN AF-P45983-K3A P45983 18 329 427.0 No_ligand No_ligand Active DFGin 6.1015 14.4206 BLAminus -131.11, 176.97 65.27, 65.06 -73.24, 10.87 295.36, 94.81 -61.15, -20.86 in-in in 9.583 Saltbr-in 2.7357 HRD-in -74.19, -48.13 61.63, 17.91 in-in-in SNCiii in-in ActLoopNT-in 2.8487 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -76.5, 167.97 APE9-dihe-na 65.01, 133.8 APE8-dihe-in -55.56, 132.77 APE8-rot-in 297.67 APE67-dihe-in -67.94, -21.16 -47.15, -46.41 APE12-dist-in 12.7744 APE11-dist-in 11.0959 APE10-dist-in 6.4288 APE9-dist-in 3.1656 None None None AF2 -1.0 1.0 1.0 A 312.0 312.0 0 27 27 0 [[26, 321]] 1.0 AF-P45983-K3 CMGC_MAPK8_HUMAN CMGC 2.4e-84 288.9 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8

PDB: AF-P45983 — CMGC MK08_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P45983-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK8 MK08_HUMAN AF-P45983-K1A P45983 18 329 427.0 No_ligand No_ligand Active DFGin 6.4146 13.6432 BLAminus -143.36, 178.91 71.76, 59.86 -79.25, 6.67 305.71, 110.21 -57.24, -28.48 in-in in 8.7613 Saltbr-in 2.7045 HRD-in -68.06, -45.26 66.86, -8.1 in-in-in SNCiii in-in ActLoopNT-in 2.7803 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -79.62, -32.38 APE9-dihe-na -74.54, 148.67 APE8-dihe-in -64.82, 122.89 APE8-rot-in 305.16 APE67-dihe-in -66.57, -21.46 -45.8, -48.81 APE12-dist-in 12.8637 APE11-dist-in 12.5239 APE10-dist-in 6.8143 APE9-dist-in 4.4072 None None None AF2 -1.0 1.0 1.0 A 312.0 312.0 0 27 27 0 [[26, 321]] 1.0 AF-P45983-K1 Homo sapiens CMGC_MAPK8_HUMAN CMGC 2.4e-84 288.9 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN AF-P45983-K3A P45983 18 329 427.0 No_ligand No_ligand Active DFGin 6.1015 14.4206 BLAminus -131.11, 176.97 65.27, 65.06 -73.24, 10.87 295.36, 94.81 -61.15, -20.86 in-in in 9.583 Saltbr-in 2.7357 HRD-in -74.19, -48.13 61.63, 17.91 in-in-in SNCiii in-in ActLoopNT-in 2.8487 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -76.5, 167.97 APE9-dihe-na 65.01, 133.8 APE8-dihe-in -55.56, 132.77 APE8-rot-in 297.67 APE67-dihe-in -67.94, -21.16 -47.15, -46.41 APE12-dist-in 12.7744 APE11-dist-in 11.0959 APE10-dist-in 6.4288 APE9-dist-in 3.1656 None None None AF2 -1.0 1.0 1.0 A 312.0 312.0 0 27 27 0 [[26, 321]] 1.0 AF-P45983-K3 Homo sapiens CMGC_MAPK8_HUMAN CMGC 2.4e-84 288.9 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8

PDB: AF-P45983 — CMGC MK08_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name