PDB: AF-P29597 — TYR TYK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P29597-K2A
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TYK2-2 TYK2_HUMAN AF-P29597-K2A P29597 889 1179 1187.0 No_ligand No_ligand Active DFGin 6.266 13.856 BLAminus -129.16, -172.6 52.17, 81.1 -91.4, 17.41 289.14, 86.02 -61.92, -27.42 in-in in 8.383 Saltbr-in 2.674 HRD-in -70.25, -42.3 64.49, -12.74 in-in-in SNCiii in-in ActLoopNT-in 2.887 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -56.3, 122.99 APE9-dihe-in -124.95, 133.41 APE8-dihe-in -75.89, 67.63 APE8-rot-na 35.61 APE67-dihe-in -74.56, -10.56 -54.18, -28.6 APE12-dist-na 13.657 APE11-dist-na 9.815 APE10-dist-na 10.236 APE9-dist-in 7.061 None None None AF2 -1.0 1.0 1.0 A 291 291 0 0 0 0 [[589, 868], [897, 1171]] 2.0 AF-P29597-K2 TYR_TYK2-2_HUMAN TYR 1.1e-81 279.9 2 260 259 1040 1041 1042 1044 1046 930 947 951 1020 1022 1021 1023 1083 1071 1066 1065 1064 1063 1062 1061 1060 979 Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-2 TYK2_HUMAN AF-P29597-K4A P29597 889 1179 1187.0 No_ligand No_ligand Active DFGin 6.336 13.879 BLAminus -129.55, -171.63 53.38, 74.68 -84.95, 17.18 288.9, 80.46 -62.16, -27.19 in-in in 8.326 Saltbr-in 2.659 HRD-in -79.84, -43.53 59.12, -2.49 in-in-in SNCiii in-in ActLoopNT-in 2.949 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -59.44, 131.09 APE9-dihe-in -129.28, 129.49 APE8-dihe-in -73.84, 63.43 APE8-rot-na 35.77 APE67-dihe-in -74.2, -11.8 -53.93, -29.14 APE12-dist-na 12.864 APE11-dist-na 9.455 APE10-dist-na 9.489 APE9-dist-in 6.739 None None None AF2 -1.0 1.0 1.0 A 291 291 0 0 0 0 [[589, 868], [897, 1171]] 2.0 AF-P29597-K4 TYR_TYK2-2_HUMAN TYR 1.1e-81 279.9 2 260 259 1040 1041 1042 1044 1046 930 947 951 1020 1022 1021 1023 1083 1071 1066 1065 1064 1063 1062 1061 1060 979 Non-receptor tyrosine-protein kinase TYK2

PDB: AF-P29597 — TYR TYK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P29597-K2A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TYK2-2 TYK2_HUMAN AF-P29597-K2A P29597 889 1179 1187.0 No_ligand No_ligand Active DFGin 6.266 13.856 BLAminus -129.16, -172.6 52.17, 81.1 -91.4, 17.41 289.14, 86.02 -61.92, -27.42 in-in in 8.383 Saltbr-in 2.674 HRD-in -70.25, -42.3 64.49, -12.74 in-in-in SNCiii in-in ActLoopNT-in 2.887 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -56.3, 122.99 APE9-dihe-in -124.95, 133.41 APE8-dihe-in -75.89, 67.63 APE8-rot-na 35.61 APE67-dihe-in -74.56, -10.56 -54.18, -28.6 APE12-dist-na 13.657 APE11-dist-na 9.815 APE10-dist-na 10.236 APE9-dist-in 7.061 None None None AF2 -1.0 1.0 1.0 A 291 291 0 0 0 0 [[589, 868], [897, 1171]] 2.0 AF-P29597-K2 Homo sapiens TYR_TYK2-2_HUMAN TYR 1.1e-81 279.9 2 260 259 1040 1041 1042 1044 1046 930 947 951 1020 1022 1021 1023 1083 1071 1066 1065 1064 1063 1062 1061 1060 979 Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-2 TYK2_HUMAN AF-P29597-K4A P29597 889 1179 1187.0 No_ligand No_ligand Active DFGin 6.336 13.879 BLAminus -129.55, -171.63 53.38, 74.68 -84.95, 17.18 288.9, 80.46 -62.16, -27.19 in-in in 8.326 Saltbr-in 2.659 HRD-in -79.84, -43.53 59.12, -2.49 in-in-in SNCiii in-in ActLoopNT-in 2.949 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -59.44, 131.09 APE9-dihe-in -129.28, 129.49 APE8-dihe-in -73.84, 63.43 APE8-rot-na 35.77 APE67-dihe-in -74.2, -11.8 -53.93, -29.14 APE12-dist-na 12.864 APE11-dist-na 9.455 APE10-dist-na 9.489 APE9-dist-in 6.739 None None None AF2 -1.0 1.0 1.0 A 291 291 0 0 0 0 [[589, 868], [897, 1171]] 2.0 AF-P29597-K4 Homo sapiens TYR_TYK2-2_HUMAN TYR 1.1e-81 279.9 2 260 259 1040 1041 1042 1044 1046 930 947 951 1020 1022 1021 1023 1083 1071 1066 1065 1064 1063 1062 1061 1060 979 Non-receptor tyrosine-protein kinase TYK2

PDB: AF-P29597 — TYR TYK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name