PDB: AF-P23458 — TYR JAK1_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P23458-K2A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN AF-P23458-K2A P23458 867 1154 1154.0 No_ligand No_ligand Active DFGin 6.307 13.7726 BLAminus -130.0, -171.31 51.92, 79.2 -91.39, 17.47 288.09, 81.21 -63.19, -25.32 in-in in 8.0857 Saltbr-in 2.7191 HRD-in -67.76, -41.14 64.22, -10.98 in-in-in SNCiii in-in ActLoopNT-in 2.9399 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -50.83, 123.48 APE9-dihe-in -125.8, 136.55 APE8-dihe-in -75.77, 67.19 APE8-rot-na 34.45 APE67-dihe-in -77.12, -11.68 -54.83, -26.9 APE12-dist-na 13.9103 APE11-dist-na 8.5318 APE10-dist-na 10.6595 APE9-dist-in 7.0627 None None None AF2 -1.0 1.0 1.0 A 288.0 288.0 0 31 31 0 [[583, 847], [875, 1151]] 2.0 AF-P23458-K2 TYR_JAK1-2_HUMAN TYR 1.8e-87 298.9 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN AF-P23458-K4A P23458 867 1154 1154.0 No_ligand No_ligand Active DFGin 6.0337 13.5522 BLAminus -127.94, -176.44 52.21, 91.21 -99.55, 15.91 293.58, 76.0 -63.9, -24.71 in-in in 7.8098 Saltbr-in 2.7151 HRD-in -69.66, -43.24 62.91, -1.77 in-in-in SNCiii in-in ActLoopNT-in 2.9198 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -47.59, 114.14 APE9-dihe-in -120.02, 146.94 APE8-dihe-in -73.57, 63.93 APE8-rot-na 37.51 APE67-dihe-in -76.35, -14.96 -54.26, -27.82 APE12-dist-na 13.6974 APE11-dist-na 8.1142 APE10-dist-na 10.9163 APE9-dist-in 6.7347 None None None AF2 -1.0 1.0 1.0 A 288.0 288.0 0 31 31 0 [[583, 847], [875, 1151]] 2.0 AF-P23458-K4 TYR_JAK1-2_HUMAN TYR 1.8e-87 298.9 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: AF-P23458 — TYR JAK1_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P23458-K2A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN AF-P23458-K2A P23458 867 1154 1154.0 No_ligand No_ligand Active DFGin 6.307 13.7726 BLAminus -130.0, -171.31 51.92, 79.2 -91.39, 17.47 288.09, 81.21 -63.19, -25.32 in-in in 8.0857 Saltbr-in 2.7191 HRD-in -67.76, -41.14 64.22, -10.98 in-in-in SNCiii in-in ActLoopNT-in 2.9399 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -50.83, 123.48 APE9-dihe-in -125.8, 136.55 APE8-dihe-in -75.77, 67.19 APE8-rot-na 34.45 APE67-dihe-in -77.12, -11.68 -54.83, -26.9 APE12-dist-na 13.9103 APE11-dist-na 8.5318 APE10-dist-na 10.6595 APE9-dist-in 7.0627 None None None AF2 -1.0 1.0 1.0 A 288.0 288.0 0 31 31 0 [[583, 847], [875, 1151]] 2.0 AF-P23458-K2 Homo sapiens TYR_JAK1-2_HUMAN TYR 1.8e-87 298.9 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN AF-P23458-K4A P23458 867 1154 1154.0 No_ligand No_ligand Active DFGin 6.0337 13.5522 BLAminus -127.94, -176.44 52.21, 91.21 -99.55, 15.91 293.58, 76.0 -63.9, -24.71 in-in in 7.8098 Saltbr-in 2.7151 HRD-in -69.66, -43.24 62.91, -1.77 in-in-in SNCiii in-in ActLoopNT-in 2.9198 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -47.59, 114.14 APE9-dihe-in -120.02, 146.94 APE8-dihe-in -73.57, 63.93 APE8-rot-na 37.51 APE67-dihe-in -76.35, -14.96 -54.26, -27.82 APE12-dist-na 13.6974 APE11-dist-na 8.1142 APE10-dist-na 10.9163 APE9-dist-in 6.7347 None None None AF2 -1.0 1.0 1.0 A 288.0 288.0 0 31 31 0 [[583, 847], [875, 1151]] 2.0 AF-P23458-K4 Homo sapiens TYR_JAK1-2_HUMAN TYR 1.8e-87 298.9 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: AF-P23458 — TYR JAK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name