PDB: AF-P08922 — TYR ROS1_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P08922-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR ROS1 ROS1_HUMAN AF-P08922-K1A P08922 1937 2225 2347.0 No_ligand No_ligand Active DFGin 6.5025 14.1756 BLAminus -131.78, -171.22 50.11, 77.85 -90.9, 16.76 289.05, 93.86 -58.64, -34.44 in-in in 8.1277 Saltbr-in 2.6701 HRD-in -79.86, -43.16 65.46, -13.8 in-in-in SNCiii in-in ActLoopNT-in 2.9676 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -65.31, 130.42 APE9-dihe-in -125.1, 138.65 APE8-dihe-in -78.85, 63.38 APE8-rot-na 34.7 APE67-dihe-in -75.99, -10.64 -43.96, -39.9 APE12-dist-na 14.6769 APE11-dist-na 10.6574 APE10-dist-na 10.1778 APE9-dist-in 6.9878 None None None AF2 -1.0 1.0 1.0 A 289.0 289.0 0 30 30 0 [[1945, 2217]] 1.0 AF-P08922-K1 TYR_ROS1_HUMAN TYR 3.7e-95 324.1 3.0 260.0 258.0 2101 2102 2103 2105 2107 1980 1997 2001 2076 2078 2077 2079.0 2143 2131 2126 2125 2124 2123 2122 2121 2120 2027 Proto-oncogene tyrosine-protein kinase ROS
TYR ROS1 ROS1_HUMAN AF-P08922-K3A P08922 1937 2225 2347.0 No_ligand No_ligand Active DFGin 6.533 13.6641 BLAminus -124.86, -166.98 52.38, 65.44 -81.98, 13.39 292.42, 96.61 -58.62, -31.96 in-in in 8.18 Saltbr-in 2.7156 HRD-in -79.6, -44.14 64.31, -4.03 in-in-in SNCiii in-in ActLoopNT-in 2.8784 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -56.23, 134.03 APE9-dihe-in -139.58, 141.95 APE8-dihe-in -80.56, 61.13 APE8-rot-na 36.67 APE67-dihe-in -68.97, -13.98 -42.55, -41.95 APE12-dist-na 14.6421 APE11-dist-na 10.885 APE10-dist-na 9.8454 APE9-dist-in 6.7643 None None None AF2 -1.0 1.0 1.0 A 289.0 289.0 0 30 30 0 [[1945, 2217]] 1.0 AF-P08922-K3 TYR_ROS1_HUMAN TYR 3.7e-95 324.1 3.0 260.0 258.0 2101 2102 2103 2105 2107 1980 1997 2001 2076 2078 2077 2079.0 2143 2131 2126 2125 2124 2123 2122 2121 2120 2027 Proto-oncogene tyrosine-protein kinase ROS

PDB: AF-P08922 — TYR ROS1_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P08922-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR ROS1 ROS1_HUMAN AF-P08922-K1A P08922 1937 2225 2347.0 No_ligand No_ligand Active DFGin 6.5025 14.1756 BLAminus -131.78, -171.22 50.11, 77.85 -90.9, 16.76 289.05, 93.86 -58.64, -34.44 in-in in 8.1277 Saltbr-in 2.6701 HRD-in -79.86, -43.16 65.46, -13.8 in-in-in SNCiii in-in ActLoopNT-in 2.9676 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -65.31, 130.42 APE9-dihe-in -125.1, 138.65 APE8-dihe-in -78.85, 63.38 APE8-rot-na 34.7 APE67-dihe-in -75.99, -10.64 -43.96, -39.9 APE12-dist-na 14.6769 APE11-dist-na 10.6574 APE10-dist-na 10.1778 APE9-dist-in 6.9878 None None None AF2 -1.0 1.0 1.0 A 289.0 289.0 0 30 30 0 [[1945, 2217]] 1.0 AF-P08922-K1 Homo sapiens TYR_ROS1_HUMAN TYR 3.7e-95 324.1 3.0 260.0 258.0 2101 2102 2103 2105 2107 1980 1997 2001 2076 2078 2077 2079.0 2143 2131 2126 2125 2124 2123 2122 2121 2120 2027 Proto-oncogene tyrosine-protein kinase ROS
TYR ROS1 ROS1_HUMAN AF-P08922-K3A P08922 1937 2225 2347.0 No_ligand No_ligand Active DFGin 6.533 13.6641 BLAminus -124.86, -166.98 52.38, 65.44 -81.98, 13.39 292.42, 96.61 -58.62, -31.96 in-in in 8.18 Saltbr-in 2.7156 HRD-in -79.6, -44.14 64.31, -4.03 in-in-in SNCiii in-in ActLoopNT-in 2.8784 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -56.23, 134.03 APE9-dihe-in -139.58, 141.95 APE8-dihe-in -80.56, 61.13 APE8-rot-na 36.67 APE67-dihe-in -68.97, -13.98 -42.55, -41.95 APE12-dist-na 14.6421 APE11-dist-na 10.885 APE10-dist-na 9.8454 APE9-dist-in 6.7643 None None None AF2 -1.0 1.0 1.0 A 289.0 289.0 0 30 30 0 [[1945, 2217]] 1.0 AF-P08922-K3 Homo sapiens TYR_ROS1_HUMAN TYR 3.7e-95 324.1 3.0 260.0 258.0 2101 2102 2103 2105 2107 1980 1997 2001 2076 2078 2077 2079.0 2143 2131 2126 2125 2124 2123 2122 2121 2120 2027 Proto-oncogene tyrosine-protein kinase ROS

PDB: AF-P08922 — TYR ROS1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name