PDB: AF-O60674 — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-O60674-K2A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN AF-O60674-K2A O60674 841 1132 1132.0 No_ligand No_ligand Active DFGin 6.0762 13.5115 BLAminus -134.61, -173.69 52.08, 73.04 -83.89, 16.61 294.74, 89.28 -62.65, -26.85 in-in in 8.2218 Saltbr-in 2.6795 HRD-in -66.64, -44.29 64.49, -16.9 in-in-in SNCiii in-in ActLoopNT-in 2.873 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -56.63, 129.01 APE9-dihe-in -134.95, 135.87 APE8-dihe-in -76.24, 67.38 APE8-rot-na 35.11 APE67-dihe-in -76.66, -11.38 -54.24, -26.75 APE12-dist-na 10.5478 APE11-dist-na 9.7769 APE10-dist-na 10.3681 APE9-dist-in 7.0163 None None None AF2 -1.0 1.0 1.0 A 292.0 292.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 AF-O60674-K2 TYR_JAK2-2_HUMAN TYR 2.4e-87 298.5 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN AF-O60674-K4A O60674 841 1132 1132.0 No_ligand No_ligand Active DFGin 6.1826 13.7278 BLAminus -124.83, -169.75 47.53, 87.52 -95.54, 11.39 291.22, 87.41 -58.23, -35.02 in-in in 8.1011 Saltbr-in 2.6898 HRD-in -71.89, -46.5 63.37, -4.19 in-in-in SNCiii in-in ActLoopNT-in 2.9389 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -53.03, 124.77 APE9-dihe-in -142.44, 144.76 APE8-dihe-in -76.91, 66.4 APE8-rot-na 36.22 APE67-dihe-in -74.84, -12.36 -51.58, -31.85 APE12-dist-na 12.6979 APE11-dist-na 9.9624 APE10-dist-na 10.3667 APE9-dist-in 6.6098 None None None AF2 -1.0 1.0 1.0 A 292.0 292.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 AF-O60674-K4 TYR_JAK2-2_HUMAN TYR 2.4e-87 298.5 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: AF-O60674 — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-O60674-K2A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN AF-O60674-K2A O60674 841 1132 1132.0 No_ligand No_ligand Active DFGin 6.0762 13.5115 BLAminus -134.61, -173.69 52.08, 73.04 -83.89, 16.61 294.74, 89.28 -62.65, -26.85 in-in in 8.2218 Saltbr-in 2.6795 HRD-in -66.64, -44.29 64.49, -16.9 in-in-in SNCiii in-in ActLoopNT-in 2.873 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -56.63, 129.01 APE9-dihe-in -134.95, 135.87 APE8-dihe-in -76.24, 67.38 APE8-rot-na 35.11 APE67-dihe-in -76.66, -11.38 -54.24, -26.75 APE12-dist-na 10.5478 APE11-dist-na 9.7769 APE10-dist-na 10.3681 APE9-dist-in 7.0163 None None None AF2 -1.0 1.0 1.0 A 292.0 292.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 AF-O60674-K2 Homo sapiens TYR_JAK2-2_HUMAN TYR 2.4e-87 298.5 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN AF-O60674-K4A O60674 841 1132 1132.0 No_ligand No_ligand Active DFGin 6.1826 13.7278 BLAminus -124.83, -169.75 47.53, 87.52 -95.54, 11.39 291.22, 87.41 -58.23, -35.02 in-in in 8.1011 Saltbr-in 2.6898 HRD-in -71.89, -46.5 63.37, -4.19 in-in-in SNCiii in-in ActLoopNT-in 2.9389 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -53.03, 124.77 APE9-dihe-in -142.44, 144.76 APE8-dihe-in -76.91, 66.4 APE8-rot-na 36.22 APE67-dihe-in -74.84, -12.36 -51.58, -31.85 APE12-dist-na 12.6979 APE11-dist-na 9.9624 APE10-dist-na 10.3667 APE9-dist-in 6.6098 None None None AF2 -1.0 1.0 1.0 A 292.0 292.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 AF-O60674-K4 Homo sapiens TYR_JAK2-2_HUMAN TYR 2.4e-87 298.5 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: AF-O60674 — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name