PDB: 9ESV — CMGC CDK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9ESVA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 9ESVC P24941 1 295 298.0 3Z7:60501,3Z7:60502 Type1,Allosteric Active DFGin 6.768 15.236 BLAminus -139.75, 176.56 54.81, 81.21 -90.94, 16.67 278.85, 71.78 -56.97, -37.98 in-in in 8.453 Saltbr-in 2.882 HRD-in -80.1, -61.08 77.4, 12.62 in-in-in SNCiii in-in ActLoopNT-in 2.891 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -69.79, 159.88 APE9-dihe-na 80.45, 128.43 APE8-dihe-in -53.65, 150.6 APE8-rot-in 315.25 APE67-dihe-in -53.52, -24.6 -48.05, -59.38 APE12-dist-in 12.614 APE11-dist-in 11.366 APE10-dist-in 6.641 APE9-dist-in 3.219 None TPO160 TPO160 XRAY 2.397 0.227 0.229 C 302 264 31 0 0 0 [[4, 286]] 1.0 9esv CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9ESVA P24941 1 298 298.0 3Z7:60601,3Z7:60602,3Z7:60603,3Z7:60604 Type1,Allosteric,Allosteric,Allosteric Active DFGin 6.66 15.169 BLAminus -141.68, -175.45 45.66, 89.4 -98.16, 27.65 279.63, 71.93 -70.26, -29.25 in-in in 8.594 Saltbr-in 3.495 HRD-in -83.94, -54.63 72.69, 21.44 in-in-in SNCiii in-in ActLoopNT-in 2.983 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -96.28, 170.55 APE9-dihe-na 72.91, 133.83 APE8-dihe-in -55.57, 128.45 APE8-rot-in 293.2 APE67-dihe-in -57.93, -20.57 -41.03, -48.86 APE12-dist-in 12.894 APE11-dist-in 12.234 APE10-dist-in 7.324 APE9-dist-in 3.227 None TPO160 TPO160 XRAY 2.397 0.227 0.229 A 302 298 0 0 0 0 [[4, 286]] 1.0 9esv CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

PDB: 9ESV — CMGC CDK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9ESVA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 9ESVC P24941 1 295 298.0 3Z7:60501,3Z7:60502 Type1,Allosteric Active DFGin 6.768 15.236 BLAminus -139.75, 176.56 54.81, 81.21 -90.94, 16.67 278.85, 71.78 -56.97, -37.98 in-in in 8.453 Saltbr-in 2.882 HRD-in -80.1, -61.08 77.4, 12.62 in-in-in SNCiii in-in ActLoopNT-in 2.891 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -69.79, 159.88 APE9-dihe-na 80.45, 128.43 APE8-dihe-in -53.65, 150.6 APE8-rot-in 315.25 APE67-dihe-in -53.52, -24.6 -48.05, -59.38 APE12-dist-in 12.614 APE11-dist-in 11.366 APE10-dist-in 6.641 APE9-dist-in 3.219 None TPO160 TPO160 XRAY 2.397 0.227 0.229 C 302 264 31 0 0 0 [[4, 286]] 1.0 9esv Homo sapiens CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9ESVA P24941 1 298 298.0 3Z7:60601,3Z7:60602,3Z7:60603,3Z7:60604 Type1,Allosteric,Allosteric,Allosteric Active DFGin 6.66 15.169 BLAminus -141.68, -175.45 45.66, 89.4 -98.16, 27.65 279.63, 71.93 -70.26, -29.25 in-in in 8.594 Saltbr-in 3.495 HRD-in -83.94, -54.63 72.69, 21.44 in-in-in SNCiii in-in ActLoopNT-in 2.983 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -96.28, 170.55 APE9-dihe-na 72.91, 133.83 APE8-dihe-in -55.57, 128.45 APE8-rot-in 293.2 APE67-dihe-in -57.93, -20.57 -41.03, -48.86 APE12-dist-in 12.894 APE11-dist-in 12.234 APE10-dist-in 7.324 APE9-dist-in 3.227 None TPO160 TPO160 XRAY 2.397 0.227 0.229 A 302 298 0 0 0 0 [[4, 286]] 1.0 9esv Homo sapiens CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

PDB: 9ESV — CMGC CDK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name