PDB: 9ESQ — CMGC CDK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9ESQA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 9ESQC P24941 1 296 298.0 IT4:60301,IT4:60302,IT4:60303 Allosteric,Type1,Allosteric Active DFGin 6.624 15.291 BLAminus -137.85, -178.69 52.7, 77.3 -90.27, 19.87 278.47, 77.01 -59.18, -26.94 in-in in 8.607 Saltbr-in 2.858 HRD-in -78.68, -58.44 73.58, 9.59 in-in-in SNCiii in-in ActLoopNT-in 2.907 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -143.68, 150.97 APE9-dihe-na 74.26, 123.88 APE8-dihe-in -48.22, 139.44 APE8-rot-in 303.28 APE67-dihe-in -59.57, -21.54 -47.89, -52.58 APE12-dist-in 12.948 APE11-dist-in 10.21 APE10-dist-in 6.851 APE9-dist-in 3.189 None TPO160 TPO160 XRAY 2.38 0.206 0.21 C 302 266 30 0 0 0 [[4, 286]] 1.0 9esq CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9ESQA P24941 1 296 298.0 IT4:60601,IT4:60602,IT4:60603,IT4:60604 Type1,Allosteric,Allosteric,Allosteric Active DFGin 6.573 15.319 BLAminus -138.63, 177.23 53.97, 82.44 -94.2, 22.34 276.67, 75.86 -65.53, -24.16 in-in in 8.618 Saltbr-in 2.754 HRD-in -82.0, -53.66 73.59, 16.79 in-in-in SNCiii in-in ActLoopNT-in 3.116 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -113.91, 166.55 APE9-dihe-na 80.06, 129.5 APE8-dihe-in -59.98, 139.75 APE8-rot-in 298.87 APE67-dihe-in -65.21, -16.21 -49.51, -47.69 APE12-dist-in 13.141 APE11-dist-in 11.71 APE10-dist-in 7.098 APE9-dist-in 3.16 None TPO160 TPO160 XRAY 2.38 0.206 0.21 A 302 296 0 0 0 0 [[4, 286]] 1.0 9esq CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

PDB: 9ESQ — CMGC CDK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9ESQA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 9ESQC P24941 1 296 298.0 IT4:60301,IT4:60302,IT4:60303 Allosteric,Type1,Allosteric Active DFGin 6.624 15.291 BLAminus -137.85, -178.69 52.7, 77.3 -90.27, 19.87 278.47, 77.01 -59.18, -26.94 in-in in 8.607 Saltbr-in 2.858 HRD-in -78.68, -58.44 73.58, 9.59 in-in-in SNCiii in-in ActLoopNT-in 2.907 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -143.68, 150.97 APE9-dihe-na 74.26, 123.88 APE8-dihe-in -48.22, 139.44 APE8-rot-in 303.28 APE67-dihe-in -59.57, -21.54 -47.89, -52.58 APE12-dist-in 12.948 APE11-dist-in 10.21 APE10-dist-in 6.851 APE9-dist-in 3.189 None TPO160 TPO160 XRAY 2.38 0.206 0.21 C 302 266 30 0 0 0 [[4, 286]] 1.0 9esq Homo sapiens CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9ESQA P24941 1 296 298.0 IT4:60601,IT4:60602,IT4:60603,IT4:60604 Type1,Allosteric,Allosteric,Allosteric Active DFGin 6.573 15.319 BLAminus -138.63, 177.23 53.97, 82.44 -94.2, 22.34 276.67, 75.86 -65.53, -24.16 in-in in 8.618 Saltbr-in 2.754 HRD-in -82.0, -53.66 73.59, 16.79 in-in-in SNCiii in-in ActLoopNT-in 3.116 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -113.91, 166.55 APE9-dihe-na 80.06, 129.5 APE8-dihe-in -59.98, 139.75 APE8-rot-in 298.87 APE67-dihe-in -65.21, -16.21 -49.51, -47.69 APE12-dist-in 13.141 APE11-dist-in 11.71 APE10-dist-in 7.098 APE9-dist-in 3.16 None TPO160 TPO160 XRAY 2.38 0.206 0.21 A 302 296 0 0 0 0 [[4, 286]] 1.0 9esq Homo sapiens CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

PDB: 9ESQ — CMGC CDK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name