PDB: 9ESO — CMGC CDK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9ESOA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 9ESOA P24941 1 298 298.0 W3A:60301 Allosteric Active DFGin 6.655 15.333 BLAminus -133.46, 169.39 64.14, 82.09 -97.29, 14.96 280.13, 78.42 -56.82, -27.72 in-in in 8.694 Saltbr-in 3.304 HRD-in -71.79, -59.63 73.42, 20.06 in-in-in SNCiii in-in ActLoopNT-in 2.908 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.56, 143.18 APE9-dihe-na 74.31, 127.7 APE8-dihe-in -57.08, 127.99 APE8-rot-in 287.92 APE67-dihe-in -62.74, -22.87 -45.7, -44.34 APE12-dist-in 12.977 APE11-dist-in 9.73 APE10-dist-in 7.242 APE9-dist-in 3.262 None TPO160 TPO160 XRAY 2.396 0.218 0.221 A 302 298 0 0 0 0 [[4, 286]] 1.0 9eso CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9ESOC P24941 1 296 298.0 W3A:60301,W3A:60302,W3A:60303 Allosteric,Type1,Allosteric Active DFGin 6.705 15.576 BLAminus -143.57, -178.71 50.73, 75.02 -85.85, 27.87 280.03, 72.76 -67.71, -29.24 in-in in 8.582 Saltbr-in 3.079 HRD-in -81.26, -57.04 69.4, 12.91 in-in-in SNCiii in-in ActLoopNT-in 2.873 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.88, 143.3 APE9-dihe-na 78.39, 127.52 APE8-dihe-in -56.1, 139.77 APE8-rot-in 304.79 APE67-dihe-in -52.87, -28.83 -47.3, -55.08 APE12-dist-in 12.645 APE11-dist-in 9.983 APE10-dist-in 7.188 APE9-dist-in 3.204 None TPO160 TPO160 XRAY 2.396 0.218 0.221 C 302 296 0 0 0 0 [[4, 286]] 1.0 9eso CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

PDB: 9ESO — CMGC CDK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9ESOA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 9ESOA P24941 1 298 298.0 W3A:60301 Allosteric Active DFGin 6.655 15.333 BLAminus -133.46, 169.39 64.14, 82.09 -97.29, 14.96 280.13, 78.42 -56.82, -27.72 in-in in 8.694 Saltbr-in 3.304 HRD-in -71.79, -59.63 73.42, 20.06 in-in-in SNCiii in-in ActLoopNT-in 2.908 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.56, 143.18 APE9-dihe-na 74.31, 127.7 APE8-dihe-in -57.08, 127.99 APE8-rot-in 287.92 APE67-dihe-in -62.74, -22.87 -45.7, -44.34 APE12-dist-in 12.977 APE11-dist-in 9.73 APE10-dist-in 7.242 APE9-dist-in 3.262 None TPO160 TPO160 XRAY 2.396 0.218 0.221 A 302 298 0 0 0 0 [[4, 286]] 1.0 9eso Homo sapiens CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9ESOC P24941 1 296 298.0 W3A:60301,W3A:60302,W3A:60303 Allosteric,Type1,Allosteric Active DFGin 6.705 15.576 BLAminus -143.57, -178.71 50.73, 75.02 -85.85, 27.87 280.03, 72.76 -67.71, -29.24 in-in in 8.582 Saltbr-in 3.079 HRD-in -81.26, -57.04 69.4, 12.91 in-in-in SNCiii in-in ActLoopNT-in 2.873 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.88, 143.3 APE9-dihe-na 78.39, 127.52 APE8-dihe-in -56.1, 139.77 APE8-rot-in 304.79 APE67-dihe-in -52.87, -28.83 -47.3, -55.08 APE12-dist-in 12.645 APE11-dist-in 9.983 APE10-dist-in 7.188 APE9-dist-in 3.204 None TPO160 TPO160 XRAY 2.396 0.218 0.221 C 302 296 0 0 0 0 [[4, 286]] 1.0 9eso Homo sapiens CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

PDB: 9ESO — CMGC CDK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name