PDB: 9ESK — CMGC CDK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9ESKC
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 9ESKC P24941 1 296 298.0 W3D:60501,W3D:60502 Type1,Allosteric Active DFGin 6.638 15.284 BLAminus -137.51, -173.46 49.66, 73.42 -88.73, 25.05 278.15, 71.06 -63.4, -24.24 in-in in 8.507 Saltbr-in 2.776 HRD-in -81.97, -57.15 70.97, 10.51 in-in-in SNCiii in-in ActLoopNT-in 2.927 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.08, 143.45 APE9-dihe-na 79.68, 124.98 APE8-dihe-in -55.57, 144.7 APE8-rot-in 305.12 APE67-dihe-in -55.94, -29.23 -48.29, -54.73 APE12-dist-in 12.79 APE11-dist-in 10.221 APE10-dist-in 6.996 APE9-dist-in 3.215 None TPO160 TPO160 XRAY 2.398 0.211 0.217 C 302 296 0 0 0 0 [[4, 286]] 1.0 9esk CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9ESKA P24941 1 298 298.0 W3D:60601,W3D:60602,W3D:60603 Type1,Allosteric,Allosteric Active DFGin 6.761 15.251 BLAminus -134.47, 176.96 63.67, 79.26 -100.81, 21.22 280.31, 65.37 -78.45, -3.37 in-in in 8.832 Saltbr-in 3.149 HRD-in -81.68, -58.97 75.36, 18.24 in-in-in SNCiii in-in ActLoopNT-in 2.999 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.89, 148.76 APE9-dihe-na 77.48, 128.01 APE8-dihe-in -56.0, 131.29 APE8-rot-in 290.87 APE67-dihe-in -61.94, -19.93 -42.42, -49.49 APE12-dist-in 12.912 APE11-dist-in 10.136 APE10-dist-in 7.275 APE9-dist-in 3.215 None TPO160 TPO160 XRAY 2.398 0.211 0.217 A 302 298 0 0 0 0 [[4, 286]] 1.0 9esk CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

PDB: 9ESK — CMGC CDK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9ESKC
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 9ESKC P24941 1 296 298.0 W3D:60501,W3D:60502 Type1,Allosteric Active DFGin 6.638 15.284 BLAminus -137.51, -173.46 49.66, 73.42 -88.73, 25.05 278.15, 71.06 -63.4, -24.24 in-in in 8.507 Saltbr-in 2.776 HRD-in -81.97, -57.15 70.97, 10.51 in-in-in SNCiii in-in ActLoopNT-in 2.927 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.08, 143.45 APE9-dihe-na 79.68, 124.98 APE8-dihe-in -55.57, 144.7 APE8-rot-in 305.12 APE67-dihe-in -55.94, -29.23 -48.29, -54.73 APE12-dist-in 12.79 APE11-dist-in 10.221 APE10-dist-in 6.996 APE9-dist-in 3.215 None TPO160 TPO160 XRAY 2.398 0.211 0.217 C 302 296 0 0 0 0 [[4, 286]] 1.0 9esk Homo sapiens CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9ESKA P24941 1 298 298.0 W3D:60601,W3D:60602,W3D:60603 Type1,Allosteric,Allosteric Active DFGin 6.761 15.251 BLAminus -134.47, 176.96 63.67, 79.26 -100.81, 21.22 280.31, 65.37 -78.45, -3.37 in-in in 8.832 Saltbr-in 3.149 HRD-in -81.68, -58.97 75.36, 18.24 in-in-in SNCiii in-in ActLoopNT-in 2.999 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.89, 148.76 APE9-dihe-na 77.48, 128.01 APE8-dihe-in -56.0, 131.29 APE8-rot-in 290.87 APE67-dihe-in -61.94, -19.93 -42.42, -49.49 APE12-dist-in 12.912 APE11-dist-in 10.136 APE10-dist-in 7.275 APE9-dist-in 3.215 None TPO160 TPO160 XRAY 2.398 0.211 0.217 A 302 298 0 0 0 0 [[4, 286]] 1.0 9esk Homo sapiens CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

PDB: 9ESK — CMGC CDK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name