PDB: 9CY5 — CMGC DYR1A_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9CY5B
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 9CY5A Q13627 136 480 763.0 A1A04:500 Type1 Active DFGin 7.147 14.638 BLAminus -122.0, 166.0 76.85, 87.4 -105.55, 21.68 282.78, 84.23 -69.73, -24.49 in-in in 8.504 Saltbr-in 2.313 HRD-in -59.7, -51.34 83.68, -0.54 in-in-in SNCiii in-in ActLoopNT-in 2.771 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -96.54, 173.95 APE9-dihe-na 71.15, 158.37 APE8-dihe-in -75.95, 126.8 APE8-rot-in 288.5 APE67-dihe-in -59.95, -29.92 -35.82, -50.5 APE12-dist-in 12.757 APE11-dist-in 12.226 APE10-dist-in 7.349 APE9-dist-in 3.057 None PTR321 PTR321 XRAY 2.49 0.203 0.259 A 365 339 6 0 0 0 [[159, 479]] 1.0 9cy5 CMGC_DYRK1A_HUMAN CMGC 8.8e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 9CY5B Q13627 135 481 763.0 A1A04:500 Type1 Active DFGin 7.251 14.584 BLAminus -112.93, 162.83 79.63, 82.51 -96.96, 24.75 288.34, 80.4 -53.23, -41.67 in-in in 8.584 Saltbr-in 2.866 HRD-in -66.43, -49.68 77.31, -1.94 in-in-in SNCiii in-in ActLoopNT-in 2.863 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -92.97, 173.98 APE9-dihe-na 79.25, 156.99 APE8-dihe-in -84.96, 136.04 APE8-rot-in 282.61 APE67-dihe-in -62.99, -28.41 -37.15, -54.75 APE12-dist-in 12.739 APE11-dist-in 12.286 APE10-dist-in 7.174 APE9-dist-in 3.17 None PTR321 PTR321 XRAY 2.49 0.203 0.259 B 365 342 5 0 0 0 [[159, 479]] 1.0 9cy5 CMGC_DYRK1A_HUMAN CMGC 8.8e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

PDB: 9CY5 — CMGC DYR1A_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9CY5B
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 9CY5A Q13627 136 480 763.0 A1A04:500 Type1 Active DFGin 7.147 14.638 BLAminus -122.0, 166.0 76.85, 87.4 -105.55, 21.68 282.78, 84.23 -69.73, -24.49 in-in in 8.504 Saltbr-in 2.313 HRD-in -59.7, -51.34 83.68, -0.54 in-in-in SNCiii in-in ActLoopNT-in 2.771 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -96.54, 173.95 APE9-dihe-na 71.15, 158.37 APE8-dihe-in -75.95, 126.8 APE8-rot-in 288.5 APE67-dihe-in -59.95, -29.92 -35.82, -50.5 APE12-dist-in 12.757 APE11-dist-in 12.226 APE10-dist-in 7.349 APE9-dist-in 3.057 None PTR321 PTR321 XRAY 2.49 0.203 0.259 A 365 339 6 0 0 0 [[159, 479]] 1.0 9cy5 Homo sapiens CMGC_DYRK1A_HUMAN CMGC 8.8e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 9CY5B Q13627 135 481 763.0 A1A04:500 Type1 Active DFGin 7.251 14.584 BLAminus -112.93, 162.83 79.63, 82.51 -96.96, 24.75 288.34, 80.4 -53.23, -41.67 in-in in 8.584 Saltbr-in 2.866 HRD-in -66.43, -49.68 77.31, -1.94 in-in-in SNCiii in-in ActLoopNT-in 2.863 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -92.97, 173.98 APE9-dihe-na 79.25, 156.99 APE8-dihe-in -84.96, 136.04 APE8-rot-in 282.61 APE67-dihe-in -62.99, -28.41 -37.15, -54.75 APE12-dist-in 12.739 APE11-dist-in 12.286 APE10-dist-in 7.174 APE9-dist-in 3.17 None PTR321 PTR321 XRAY 2.49 0.203 0.259 B 365 342 5 0 0 0 [[159, 479]] 1.0 9cy5 Homo sapiens CMGC_DYRK1A_HUMAN CMGC 8.8e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

PDB: 9CY5 — CMGC DYR1A_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name