Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | SYK | KSYK_HUMAN | 8XQ0A | P43405 | 364 | 634 | 635.0 | A1LV4:701 | Type1 | Active | DFGin | 6.154 | 14.743 | BLAminus | -131.25, -165.27 | 59.08, 66.28 | -91.94, 24.84 | 295.79, 89.46 | -66.54, -26.0 | in-in | in | 8.841 | Saltbr-in | 2.39 | HRD-in | -77.49, -50.4 | 67.59, 11.98 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.763 | ActLoopCT-in | TYR | APEdihe_iiiai | APEdist_aaai | APE10-dihe-in | -69.4, 148.65 | APE9-dihe-in | -142.22, 83.4 | APE8-dihe-in | -79.88, 80.85 | APE8-rot-na | 30.05 | APE67-dihe-in | -71.39, -10.32 | -63.91, -29.36 | APE12-dist-na | 999.0 | APE11-dist-na | 8.661 | APE10-dist-na | 7.465 | APE9-dist-in | 7.084 | None | None | None | XRAY | 1.95 | 0.222 | 0.265 | A | 290 | 264 | 7 | 0 | 0 | 4 | [[370, 628]] | 1.0 | 8xq0 | TYR_SYK_HUMAN | TYR | 5.4e-90 | 307.1 | 5 | 260 | 256 | 511 | 512 | 513 | 515 | 517 | 402 | 420 | 424 | 491 | 493 | 492 | 494 | 554 | 542 | 537 | 536 | 535 | 534 | 533 | 532 | 531 | 449 | Tyrosine-protein kinase SYK |
| TYR | SYK | KSYK_HUMAN | 8XQ0B | P43405 | 364 | 634 | 635.0 | A1LV4:701 | Type1 | None | DFGin | 6.294 | 14.269 | BLAminus | -121.56, -165.09 | 54.01, 77.14 | -98.56, 23.24 | 296.48, 92.65 | -61.88, -28.43 | in-in | in | 8.418 | Saltbr-in | 2.649 | HRD-in | -77.64, -48.09 | 70.42, 13.58 | in-in-none | SNCiin | in-none | ActLoopNT-in | 2.796 | ActLoopCT-none | TYR | APEdihe_niiai | APEdist_aaai | APE10-dihe-none | 999.0, 110.46 | APE9-dihe-in | -140.12, 100.43 | APE8-dihe-in | -73.17, 75.7 | APE8-rot-na | 30.62 | APE67-dihe-in | -68.44, -13.24 | -66.75, -26.44 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 7.655 | APE9-dist-in | 6.875 | None | None | None | XRAY | 1.95 | 0.222 | 0.265 | B | 290 | 253 | 18 | 0 | 0 | 4 | [[370, 628]] | 1.0 | 8xq0 | TYR_SYK_HUMAN | TYR | 5.4e-90 | 307.1 | 5 | 260 | 256 | 511 | 512 | 513 | 515 | 517 | 402 | 420 | 424 | 491 | 493 | 492 | 494 | 554 | 542 | 537 | 536 | 535 | 534 | 533 | 532 | 531 | 449 | Tyrosine-protein kinase SYK |
| TYR | SYK | KSYK_HUMAN | 8XQ0C | P43405 | 364 | 633 | 635.0 | A1LV4:701 | Type1 | Active | DFGin | 6.064 | 14.771 | BLAminus | -131.08, -166.05 | 60.61, 65.77 | -92.17, 22.95 | 297.06, 91.43 | -65.35, -22.59 | in-in | in | 8.197 | Saltbr-in | 2.474 | HRD-in | -81.66, -50.49 | 70.19, 9.23 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.862 | ActLoopCT-in | TYR | APEdihe_iiiai | APEdist_aaai | APE10-dihe-in | -70.0, 152.43 | APE9-dihe-in | -139.04, 83.13 | APE8-dihe-in | -80.21, 76.04 | APE8-rot-na | 29.28 | APE67-dihe-in | -67.25, -12.04 | -57.38, -34.01 | APE12-dist-na | 999.0 | APE11-dist-na | 8.547 | APE10-dist-na | 7.75 | APE9-dist-in | 7.186 | None | None | None | XRAY | 1.95 | 0.222 | 0.265 | C | 290 | 263 | 7 | 0 | 0 | 3 | [[370, 628]] | 1.0 | 8xq0 | TYR_SYK_HUMAN | TYR | 5.4e-90 | 307.1 | 5 | 260 | 256 | 511 | 512 | 513 | 515 | 517 | 402 | 420 | 424 | 491 | 493 | 492 | 494 | 554 | 542 | 537 | 536 | 535 | 534 | 533 | 532 | 531 | 449 | Tyrosine-protein kinase SYK |
| TYR | SYK | KSYK_HUMAN | 8XQ0D | P43405 | 364 | 635 | 635.0 | A1LV4:701 | Type1 | None | DFGin | 6.314 | 14.39 | BLAminus | -120.19, -170.79 | 65.2, 70.98 | -95.79, 24.62 | 295.16, 93.42 | -63.39, -28.44 | in-in | in | 8.488 | Saltbr-in | 2.701 | HRD-in | -76.01, -49.61 | 70.34, 8.1 | in-in-none | SNCiin | in-none | ActLoopNT-in | 2.787 | ActLoopCT-none | TYR | APEdihe_niiai | APEdist_aaai | APE10-dihe-none | 999.0, 140.86 | APE9-dihe-in | -154.41, 100.57 | APE8-dihe-in | -72.25, 67.88 | APE8-rot-na | 28.73 | APE67-dihe-in | -63.58, -17.28 | -53.94, -36.05 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 8.164 | APE9-dist-in | 6.963 | None | None | None | XRAY | 1.95 | 0.222 | 0.265 | D | 290 | 258 | 14 | 0 | 0 | 4 | [[370, 628]] | 1.0 | 8xq0 | TYR_SYK_HUMAN | TYR | 5.4e-90 | 307.1 | 5 | 260 | 256 | 511 | 512 | 513 | 515 | 517 | 402 | 420 | 424 | 491 | 493 | 492 | 494 | 554 | 542 | 537 | 536 | 535 | 534 | 533 | 532 | 531 | 449 | Tyrosine-protein kinase SYK |
Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | SYK | KSYK_HUMAN | 8XQ0A | P43405 | 364 | 634 | 635.0 | A1LV4:701 | Type1 | Active | DFGin | 6.154 | 14.743 | BLAminus | -131.25, -165.27 | 59.08, 66.28 | -91.94, 24.84 | 295.79, 89.46 | -66.54, -26.0 | in-in | in | 8.841 | Saltbr-in | 2.39 | HRD-in | -77.49, -50.4 | 67.59, 11.98 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.763 | ActLoopCT-in | TYR | APEdihe_iiiai | APEdist_aaai | APE10-dihe-in | -69.4, 148.65 | APE9-dihe-in | -142.22, 83.4 | APE8-dihe-in | -79.88, 80.85 | APE8-rot-na | 30.05 | APE67-dihe-in | -71.39, -10.32 | -63.91, -29.36 | APE12-dist-na | 999.0 | APE11-dist-na | 8.661 | APE10-dist-na | 7.465 | APE9-dist-in | 7.084 | None | None | None | XRAY | 1.95 | 0.222 | 0.265 | A | 290 | 264 | 7 | 0 | 0 | 4 | [[370, 628]] | 1.0 | 8xq0 | Homo sapiens | TYR_SYK_HUMAN | TYR | 5.4e-90 | 307.1 | 5 | 260 | 256 | 511 | 512 | 513 | 515 | 517 | 402 | 420 | 424 | 491 | 493 | 492 | 494 | 554 | 542 | 537 | 536 | 535 | 534 | 533 | 532 | 531 | 449 | Tyrosine-protein kinase SYK |
| TYR | SYK | KSYK_HUMAN | 8XQ0B | P43405 | 364 | 634 | 635.0 | A1LV4:701 | Type1 | None | DFGin | 6.294 | 14.269 | BLAminus | -121.56, -165.09 | 54.01, 77.14 | -98.56, 23.24 | 296.48, 92.65 | -61.88, -28.43 | in-in | in | 8.418 | Saltbr-in | 2.649 | HRD-in | -77.64, -48.09 | 70.42, 13.58 | in-in-none | SNCiin | in-none | ActLoopNT-in | 2.796 | ActLoopCT-none | TYR | APEdihe_niiai | APEdist_aaai | APE10-dihe-none | 999.0, 110.46 | APE9-dihe-in | -140.12, 100.43 | APE8-dihe-in | -73.17, 75.7 | APE8-rot-na | 30.62 | APE67-dihe-in | -68.44, -13.24 | -66.75, -26.44 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 7.655 | APE9-dist-in | 6.875 | None | None | None | XRAY | 1.95 | 0.222 | 0.265 | B | 290 | 253 | 18 | 0 | 0 | 4 | [[370, 628]] | 1.0 | 8xq0 | Homo sapiens | TYR_SYK_HUMAN | TYR | 5.4e-90 | 307.1 | 5 | 260 | 256 | 511 | 512 | 513 | 515 | 517 | 402 | 420 | 424 | 491 | 493 | 492 | 494 | 554 | 542 | 537 | 536 | 535 | 534 | 533 | 532 | 531 | 449 | Tyrosine-protein kinase SYK |
| TYR | SYK | KSYK_HUMAN | 8XQ0C | P43405 | 364 | 633 | 635.0 | A1LV4:701 | Type1 | Active | DFGin | 6.064 | 14.771 | BLAminus | -131.08, -166.05 | 60.61, 65.77 | -92.17, 22.95 | 297.06, 91.43 | -65.35, -22.59 | in-in | in | 8.197 | Saltbr-in | 2.474 | HRD-in | -81.66, -50.49 | 70.19, 9.23 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.862 | ActLoopCT-in | TYR | APEdihe_iiiai | APEdist_aaai | APE10-dihe-in | -70.0, 152.43 | APE9-dihe-in | -139.04, 83.13 | APE8-dihe-in | -80.21, 76.04 | APE8-rot-na | 29.28 | APE67-dihe-in | -67.25, -12.04 | -57.38, -34.01 | APE12-dist-na | 999.0 | APE11-dist-na | 8.547 | APE10-dist-na | 7.75 | APE9-dist-in | 7.186 | None | None | None | XRAY | 1.95 | 0.222 | 0.265 | C | 290 | 263 | 7 | 0 | 0 | 3 | [[370, 628]] | 1.0 | 8xq0 | Homo sapiens | TYR_SYK_HUMAN | TYR | 5.4e-90 | 307.1 | 5 | 260 | 256 | 511 | 512 | 513 | 515 | 517 | 402 | 420 | 424 | 491 | 493 | 492 | 494 | 554 | 542 | 537 | 536 | 535 | 534 | 533 | 532 | 531 | 449 | Tyrosine-protein kinase SYK |
| TYR | SYK | KSYK_HUMAN | 8XQ0D | P43405 | 364 | 635 | 635.0 | A1LV4:701 | Type1 | None | DFGin | 6.314 | 14.39 | BLAminus | -120.19, -170.79 | 65.2, 70.98 | -95.79, 24.62 | 295.16, 93.42 | -63.39, -28.44 | in-in | in | 8.488 | Saltbr-in | 2.701 | HRD-in | -76.01, -49.61 | 70.34, 8.1 | in-in-none | SNCiin | in-none | ActLoopNT-in | 2.787 | ActLoopCT-none | TYR | APEdihe_niiai | APEdist_aaai | APE10-dihe-none | 999.0, 140.86 | APE9-dihe-in | -154.41, 100.57 | APE8-dihe-in | -72.25, 67.88 | APE8-rot-na | 28.73 | APE67-dihe-in | -63.58, -17.28 | -53.94, -36.05 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 8.164 | APE9-dist-in | 6.963 | None | None | None | XRAY | 1.95 | 0.222 | 0.265 | D | 290 | 258 | 14 | 0 | 0 | 4 | [[370, 628]] | 1.0 | 8xq0 | Homo sapiens | TYR_SYK_HUMAN | TYR | 5.4e-90 | 307.1 | 5 | 260 | 256 | 511 | 512 | 513 | 515 | 517 | 402 | 420 | 424 | 491 | 493 | 492 | 494 | 554 | 542 | 537 | 536 | 535 | 534 | 533 | 532 | 531 | 449 | Tyrosine-protein kinase SYK |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|