PDB: 8S19 — TYR KIT_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8S19A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 8S19A P10721 566 931 976.0 STU:61001 Type1 Active DFGin 7.4038 13.6674 BLAminus -127.12, -176.58 57.62, 86.03 -104.33, 27.64 287.94, 75.89 -65.62, -32.19 in-in in 8.5279 Saltbr-in 2.8072 HRD-in -86.95, -44.99 76.04, 4.46 in-in-in SNCiii in-in ActLoopNT-in 2.9798 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -67.78, 135.36 APE9-dihe-in -116.81, 146.55 APE8-dihe-in -80.8, 82.76 APE8-rot-na 31.59 APE67-dihe-in -71.09, -10.53 -60.41, -40.84 APE12-dist-na 14.6501 APE11-dist-na 10.0069 APE10-dist-na 13.4676 APE9-dist-in 7.8988 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.3 0.186 0.208 A 327.0 287.0 1 30 29 1 [[589, 926]] 1.0 8s19 TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S19B P10721 566 930 976.0 STU:61001 Type1 Active DFGin 7.3271 13.5376 BLAminus -128.07, -176.35 62.24, 79.08 -101.65, 27.17 286.46, 78.41 -65.78, -31.3 in-in in 8.4236 Saltbr-in 3.2444 HRD-in -86.63, -46.82 74.21, 3.84 in-in-in SNCiii in-in ActLoopNT-in 2.9724 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -67.88, 148.22 APE9-dihe-in -128.01, 146.9 APE8-dihe-in -81.2, 79.5 APE8-rot-na 31.77 APE67-dihe-in -74.43, -9.18 -60.72, -38.08 APE12-dist-na 14.1209 APE11-dist-na 10.1321 APE10-dist-na 13.2289 APE9-dist-in 7.6951 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.3 0.186 0.208 B 327.0 284.0 3 30 30 0 [[589, 926]] 1.0 8s19 TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

PDB: 8S19 — TYR KIT_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8S19A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 8S19A P10721 566 931 976.0 STU:61001 Type1 Active DFGin 7.4038 13.6674 BLAminus -127.12, -176.58 57.62, 86.03 -104.33, 27.64 287.94, 75.89 -65.62, -32.19 in-in in 8.5279 Saltbr-in 2.8072 HRD-in -86.95, -44.99 76.04, 4.46 in-in-in SNCiii in-in ActLoopNT-in 2.9798 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -67.78, 135.36 APE9-dihe-in -116.81, 146.55 APE8-dihe-in -80.8, 82.76 APE8-rot-na 31.59 APE67-dihe-in -71.09, -10.53 -60.41, -40.84 APE12-dist-na 14.6501 APE11-dist-na 10.0069 APE10-dist-na 13.4676 APE9-dist-in 7.8988 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.3 0.186 0.208 A 327.0 287.0 1 30 29 1 [[589, 926]] 1.0 8s19 Homo sapiens TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S19B P10721 566 930 976.0 STU:61001 Type1 Active DFGin 7.3271 13.5376 BLAminus -128.07, -176.35 62.24, 79.08 -101.65, 27.17 286.46, 78.41 -65.78, -31.3 in-in in 8.4236 Saltbr-in 3.2444 HRD-in -86.63, -46.82 74.21, 3.84 in-in-in SNCiii in-in ActLoopNT-in 2.9724 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -67.88, 148.22 APE9-dihe-in -128.01, 146.9 APE8-dihe-in -81.2, 79.5 APE8-rot-na 31.77 APE67-dihe-in -74.43, -9.18 -60.72, -38.08 APE12-dist-na 14.1209 APE11-dist-na 10.1321 APE10-dist-na 13.2289 APE9-dist-in 7.6951 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.3 0.186 0.208 B 327.0 284.0 3 30 30 0 [[589, 926]] 1.0 8s19 Homo sapiens TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

PDB: 8S19 — TYR KIT_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name