| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMK | SIK3 | SIK3_HUMAN | 8R4QA | Q9Y2K2 | 62 | 384 | 1321.0 | DB8:401 | Type1 | Inactive | DFGin | 6.2696 | 14.8874 | BLAminus | -139.01, 171.07 | 65.51, 84.49 | -98.95, 35.4 | 290.76, 86.17 | -67.45, -37.73 | in-out | in | 9.4825 | Saltbr-out | 4.139 | HRD-in | -65.82, -56.46 | 69.69, -0.35 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9584 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -131.28, 159.93 | APE9-dihe-na | 142.02, 171.32 | APE8-dihe-in | -81.41, 117.57 | APE8-rot-out | 188.89 | APE67-dihe-in | -62.69, -24.82 | -43.74, -50.05 | APE12-dist-in | 7.634 | APE11-dist-in | 11.0094 | APE10-dist-in | 5.2938 | APE9-dist-in | 3.2322 | C121S,C181S,C333S | TPO221 | TPO221 | XRAY | 2.838 | 0.214 | 0.244 | A | 328.0 | 315.0 | 0 | 27 | 27 | 0 | [[66, 317]] | 1.0 | 8r4q | CAMK_SIK3_HUMAN | CAMK | 1.8e-96 | 328.4 | 1.0 | 256.0 | 256.0 | 205 | 206 | 207 | 209 | 211 | 95 | 113 | 117 | 185 | 187 | 186 | 188.0 | 245 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 143 | Serine/threonine-protein kinase SIK3 |
| CAMK | SIK3 | SIK3_HUMAN | 8R4QC | Q9Y2K2 | 62 | 384 | 1321.0 | DB8:401 | Type1 | Inactive | DFGin | 6.2926 | 14.7635 | BLAminus | -135.25, 170.61 | 66.71, 84.0 | -99.07, 36.48 | 291.2, 85.91 | -69.03, -37.82 | in-out | in | 9.4987 | Saltbr-out | 4.06 | HRD-in | -75.57, -57.14 | 68.81, -4.17 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.8901 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -129.57, 158.49 | APE9-dihe-na | 142.55, 170.52 | APE8-dihe-in | -81.5, 119.22 | APE8-rot-out | 55.54 | APE67-dihe-in | -62.66, -24.97 | -44.86, -49.85 | APE12-dist-in | 7.6162 | APE11-dist-in | 10.9859 | APE10-dist-in | 5.2631 | APE9-dist-in | 3.2383 | C121S,C181S,C333S | TPO221 | TPO221 | XRAY | 2.838 | 0.214 | 0.244 | C | 328.0 | 315.0 | 0 | 27 | 27 | 0 | [[66, 317]] | 1.0 | 8r4q | CAMK_SIK3_HUMAN | CAMK | 1.8e-96 | 328.4 | 1.0 | 256.0 | 256.0 | 205 | 206 | 207 | 209 | 211 | 95 | 113 | 117 | 185 | 187 | 186 | 188.0 | 245 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 143 | Serine/threonine-protein kinase SIK3 |
| CAMK | SIK3 | SIK3_HUMAN | 8R4QE | Q9Y2K2 | 62 | 384 | 1321.0 | DB8:401 | Type1 | Inactive | DFGin | 6.3104 | 14.8014 | BLAminus | -139.98, 171.19 | 65.46, 83.84 | -99.17, 35.86 | 291.35, 86.11 | -68.1, -36.3 | in-out | in | 9.5316 | Saltbr-out | 4.0961 | HRD-in | -73.14, -51.55 | 63.42, 1.74 | out-in-out | SNCoio | in-out | ActLoopNT-in | 3.1013 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -130.33, 159.33 | APE9-dihe-na | 142.87, 171.07 | APE8-dihe-in | -80.24, 117.39 | APE8-rot-out | 190.21 | APE67-dihe-in | -61.05, -42.7 | -42.39, -51.02 | APE12-dist-in | 7.5429 | APE11-dist-in | 10.9393 | APE10-dist-in | 5.2591 | APE9-dist-in | 3.3317 | C121S,C181S,C333S | TPO221 | TPO221 | XRAY | 2.838 | 0.214 | 0.244 | E | 328.0 | 315.0 | 0 | 27 | 27 | 0 | [[66, 317]] | 1.0 | 8r4q | CAMK_SIK3_HUMAN | CAMK | 1.8e-96 | 328.4 | 1.0 | 256.0 | 256.0 | 205 | 206 | 207 | 209 | 211 | 95 | 113 | 117 | 185 | 187 | 186 | 188.0 | 245 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 143 | Serine/threonine-protein kinase SIK3 |
| CAMK | SIK3 | SIK3_HUMAN | 8R4QG | Q9Y2K2 | 62 | 384 | 1321.0 | DB8:401 | Type1 | Inactive | DFGin | 6.3822 | 14.7874 | BLAminus | -136.43, 170.69 | 66.72, 83.62 | -98.78, 33.02 | 291.62, 86.44 | -67.7, -37.12 | in-out | in | 9.5547 | Saltbr-out | 3.9739 | HRD-in | -68.39, -50.34 | 62.72, 11.29 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9253 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -132.11, 159.76 | APE9-dihe-na | 140.64, 172.45 | APE8-dihe-in | -81.58, 117.44 | APE8-rot-out | 189.92 | APE67-dihe-in | -60.6, -25.5 | -43.58, -51.63 | APE12-dist-in | 7.4333 | APE11-dist-in | 10.7908 | APE10-dist-in | 5.137 | APE9-dist-in | 3.2434 | C121S,C181S,C333S | TPO221 | TPO221 | XRAY | 2.838 | 0.214 | 0.244 | G | 328.0 | 320.0 | 0 | 27 | 27 | 0 | [[66, 317]] | 1.0 | 8r4q | CAMK_SIK3_HUMAN | CAMK | 1.8e-96 | 328.4 | 1.0 | 256.0 | 256.0 | 205 | 206 | 207 | 209 | 211 | 95 | 113 | 117 | 185 | 187 | 186 | 188.0 | 245 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 143 | Serine/threonine-protein kinase SIK3 |
| CAMK | SIK3 | SIK3_HUMAN | 8R4QI | Q9Y2K2 | 62 | 384 | 1321.0 | DB8:401 | Type1 | Inactive | DFGin | 6.2899 | 14.8565 | BLAminus | -140.96, 171.42 | 64.9, 84.12 | -97.96, 35.72 | 290.26, 86.39 | -67.95, -38.18 | in-out | in | 9.5445 | Saltbr-out | 4.0834 | HRD-in | -66.19, -52.55 | 62.88, 16.03 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9347 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -130.02, 158.46 | APE9-dihe-na | 144.09, 168.25 | APE8-dihe-in | -80.55, 117.37 | APE8-rot-out | 188.41 | APE67-dihe-in | -62.44, -25.32 | -44.55, -49.34 | APE12-dist-in | 7.633 | APE11-dist-in | 10.9702 | APE10-dist-in | 5.2476 | APE9-dist-in | 3.2922 | C121S,C181S,C333S | TPO221 | TPO221 | XRAY | 2.838 | 0.214 | 0.244 | I | 328.0 | 316.0 | 0 | 27 | 27 | 0 | [[66, 317]] | 1.0 | 8r4q | CAMK_SIK3_HUMAN | CAMK | 1.8e-96 | 328.4 | 1.0 | 256.0 | 256.0 | 205 | 206 | 207 | 209 | 211 | 95 | 113 | 117 | 185 | 187 | 186 | 188.0 | 245 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 143 | Serine/threonine-protein kinase SIK3 |
| CAMK | SIK3 | SIK3_HUMAN | 8R4QK | Q9Y2K2 | 62 | 384 | 1321.0 | DB8:401 | Type1 | Inactive | DFGin | 6.3028 | 14.8618 | BLAminus | -130.99, 169.6 | 63.77, 94.11 | -108.55, 39.14 | 294.05, 89.24 | -69.02, -37.64 | in-out | in | 9.9212 | Saltbr-out | 5.2015 | HRD-in | -62.64, -54.81 | 63.03, 15.84 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9832 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -127.45, 159.5 | APE9-dihe-na | 141.76, 170.37 | APE8-dihe-in | -80.52, 118.54 | APE8-rot-out | 187.31 | APE67-dihe-in | -62.28, -24.73 | -43.25, -51.12 | APE12-dist-in | 7.5208 | APE11-dist-in | 10.9604 | APE10-dist-in | 5.2231 | APE9-dist-in | 3.2543 | C121S,C181S,C333S | TPO221 | TPO221 | XRAY | 2.838 | 0.214 | 0.244 | K | 328.0 | 318.0 | 0 | 27 | 27 | 0 | [[66, 317]] | 1.0 | 8r4q | CAMK_SIK3_HUMAN | CAMK | 1.8e-96 | 328.4 | 1.0 | 256.0 | 256.0 | 205 | 206 | 207 | 209 | 211 | 95 | 113 | 117 | 185 | 187 | 186 | 188.0 | 245 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 143 | Serine/threonine-protein kinase SIK3 |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMK | SIK3 | SIK3_HUMAN | 8R4QA | Q9Y2K2 | 62 | 384 | 1321.0 | DB8:401 | Type1 | Inactive | DFGin | 6.2696 | 14.8874 | BLAminus | -139.01, 171.07 | 65.51, 84.49 | -98.95, 35.4 | 290.76, 86.17 | -67.45, -37.73 | in-out | in | 9.4825 | Saltbr-out | 4.139 | HRD-in | -65.82, -56.46 | 69.69, -0.35 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9584 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -131.28, 159.93 | APE9-dihe-na | 142.02, 171.32 | APE8-dihe-in | -81.41, 117.57 | APE8-rot-out | 188.89 | APE67-dihe-in | -62.69, -24.82 | -43.74, -50.05 | APE12-dist-in | 7.634 | APE11-dist-in | 11.0094 | APE10-dist-in | 5.2938 | APE9-dist-in | 3.2322 | C121S,C181S,C333S | TPO221 | TPO221 | XRAY | 2.838 | 0.214 | 0.244 | A | 328.0 | 315.0 | 0 | 27 | 27 | 0 | [[66, 317]] | 1.0 | 8r4q | Homo sapiens | CAMK_SIK3_HUMAN | CAMK | 1.8e-96 | 328.4 | 1.0 | 256.0 | 256.0 | 205 | 206 | 207 | 209 | 211 | 95 | 113 | 117 | 185 | 187 | 186 | 188.0 | 245 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 143 | Serine/threonine-protein kinase SIK3 |
| CAMK | SIK3 | SIK3_HUMAN | 8R4QC | Q9Y2K2 | 62 | 384 | 1321.0 | DB8:401 | Type1 | Inactive | DFGin | 6.2926 | 14.7635 | BLAminus | -135.25, 170.61 | 66.71, 84.0 | -99.07, 36.48 | 291.2, 85.91 | -69.03, -37.82 | in-out | in | 9.4987 | Saltbr-out | 4.06 | HRD-in | -75.57, -57.14 | 68.81, -4.17 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.8901 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -129.57, 158.49 | APE9-dihe-na | 142.55, 170.52 | APE8-dihe-in | -81.5, 119.22 | APE8-rot-out | 55.54 | APE67-dihe-in | -62.66, -24.97 | -44.86, -49.85 | APE12-dist-in | 7.6162 | APE11-dist-in | 10.9859 | APE10-dist-in | 5.2631 | APE9-dist-in | 3.2383 | C121S,C181S,C333S | TPO221 | TPO221 | XRAY | 2.838 | 0.214 | 0.244 | C | 328.0 | 315.0 | 0 | 27 | 27 | 0 | [[66, 317]] | 1.0 | 8r4q | Homo sapiens | CAMK_SIK3_HUMAN | CAMK | 1.8e-96 | 328.4 | 1.0 | 256.0 | 256.0 | 205 | 206 | 207 | 209 | 211 | 95 | 113 | 117 | 185 | 187 | 186 | 188.0 | 245 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 143 | Serine/threonine-protein kinase SIK3 |
| CAMK | SIK3 | SIK3_HUMAN | 8R4QE | Q9Y2K2 | 62 | 384 | 1321.0 | DB8:401 | Type1 | Inactive | DFGin | 6.3104 | 14.8014 | BLAminus | -139.98, 171.19 | 65.46, 83.84 | -99.17, 35.86 | 291.35, 86.11 | -68.1, -36.3 | in-out | in | 9.5316 | Saltbr-out | 4.0961 | HRD-in | -73.14, -51.55 | 63.42, 1.74 | out-in-out | SNCoio | in-out | ActLoopNT-in | 3.1013 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -130.33, 159.33 | APE9-dihe-na | 142.87, 171.07 | APE8-dihe-in | -80.24, 117.39 | APE8-rot-out | 190.21 | APE67-dihe-in | -61.05, -42.7 | -42.39, -51.02 | APE12-dist-in | 7.5429 | APE11-dist-in | 10.9393 | APE10-dist-in | 5.2591 | APE9-dist-in | 3.3317 | C121S,C181S,C333S | TPO221 | TPO221 | XRAY | 2.838 | 0.214 | 0.244 | E | 328.0 | 315.0 | 0 | 27 | 27 | 0 | [[66, 317]] | 1.0 | 8r4q | Homo sapiens | CAMK_SIK3_HUMAN | CAMK | 1.8e-96 | 328.4 | 1.0 | 256.0 | 256.0 | 205 | 206 | 207 | 209 | 211 | 95 | 113 | 117 | 185 | 187 | 186 | 188.0 | 245 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 143 | Serine/threonine-protein kinase SIK3 |
| CAMK | SIK3 | SIK3_HUMAN | 8R4QG | Q9Y2K2 | 62 | 384 | 1321.0 | DB8:401 | Type1 | Inactive | DFGin | 6.3822 | 14.7874 | BLAminus | -136.43, 170.69 | 66.72, 83.62 | -98.78, 33.02 | 291.62, 86.44 | -67.7, -37.12 | in-out | in | 9.5547 | Saltbr-out | 3.9739 | HRD-in | -68.39, -50.34 | 62.72, 11.29 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9253 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -132.11, 159.76 | APE9-dihe-na | 140.64, 172.45 | APE8-dihe-in | -81.58, 117.44 | APE8-rot-out | 189.92 | APE67-dihe-in | -60.6, -25.5 | -43.58, -51.63 | APE12-dist-in | 7.4333 | APE11-dist-in | 10.7908 | APE10-dist-in | 5.137 | APE9-dist-in | 3.2434 | C121S,C181S,C333S | TPO221 | TPO221 | XRAY | 2.838 | 0.214 | 0.244 | G | 328.0 | 320.0 | 0 | 27 | 27 | 0 | [[66, 317]] | 1.0 | 8r4q | Homo sapiens | CAMK_SIK3_HUMAN | CAMK | 1.8e-96 | 328.4 | 1.0 | 256.0 | 256.0 | 205 | 206 | 207 | 209 | 211 | 95 | 113 | 117 | 185 | 187 | 186 | 188.0 | 245 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 143 | Serine/threonine-protein kinase SIK3 |
| CAMK | SIK3 | SIK3_HUMAN | 8R4QI | Q9Y2K2 | 62 | 384 | 1321.0 | DB8:401 | Type1 | Inactive | DFGin | 6.2899 | 14.8565 | BLAminus | -140.96, 171.42 | 64.9, 84.12 | -97.96, 35.72 | 290.26, 86.39 | -67.95, -38.18 | in-out | in | 9.5445 | Saltbr-out | 4.0834 | HRD-in | -66.19, -52.55 | 62.88, 16.03 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9347 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -130.02, 158.46 | APE9-dihe-na | 144.09, 168.25 | APE8-dihe-in | -80.55, 117.37 | APE8-rot-out | 188.41 | APE67-dihe-in | -62.44, -25.32 | -44.55, -49.34 | APE12-dist-in | 7.633 | APE11-dist-in | 10.9702 | APE10-dist-in | 5.2476 | APE9-dist-in | 3.2922 | C121S,C181S,C333S | TPO221 | TPO221 | XRAY | 2.838 | 0.214 | 0.244 | I | 328.0 | 316.0 | 0 | 27 | 27 | 0 | [[66, 317]] | 1.0 | 8r4q | Homo sapiens | CAMK_SIK3_HUMAN | CAMK | 1.8e-96 | 328.4 | 1.0 | 256.0 | 256.0 | 205 | 206 | 207 | 209 | 211 | 95 | 113 | 117 | 185 | 187 | 186 | 188.0 | 245 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 143 | Serine/threonine-protein kinase SIK3 |
| CAMK | SIK3 | SIK3_HUMAN | 8R4QK | Q9Y2K2 | 62 | 384 | 1321.0 | DB8:401 | Type1 | Inactive | DFGin | 6.3028 | 14.8618 | BLAminus | -130.99, 169.6 | 63.77, 94.11 | -108.55, 39.14 | 294.05, 89.24 | -69.02, -37.64 | in-out | in | 9.9212 | Saltbr-out | 5.2015 | HRD-in | -62.64, -54.81 | 63.03, 15.84 | out-in-out | SNCoio | in-out | ActLoopNT-in | 2.9832 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -127.45, 159.5 | APE9-dihe-na | 141.76, 170.37 | APE8-dihe-in | -80.52, 118.54 | APE8-rot-out | 187.31 | APE67-dihe-in | -62.28, -24.73 | -43.25, -51.12 | APE12-dist-in | 7.5208 | APE11-dist-in | 10.9604 | APE10-dist-in | 5.2231 | APE9-dist-in | 3.2543 | C121S,C181S,C333S | TPO221 | TPO221 | XRAY | 2.838 | 0.214 | 0.244 | K | 328.0 | 318.0 | 0 | 27 | 27 | 0 | [[66, 317]] | 1.0 | 8r4q | Homo sapiens | CAMK_SIK3_HUMAN | CAMK | 1.8e-96 | 328.4 | 1.0 | 256.0 | 256.0 | 205 | 206 | 207 | 209 | 211 | 95 | 113 | 117 | 185 | 187 | 186 | 188.0 | 245 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 143 | Serine/threonine-protein kinase SIK3 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
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