PDB: 8R4Q — CAMK SIK3_HUMAN

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 100.0% 8R4QA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK SIK3 SIK3_HUMAN 8R4QA Q9Y2K2 62 384 1321.0 DB8:401 Type1 Inactive DFGin 6.27 14.887 BLAminus -139.01, 171.07 65.51, 84.49 -98.95, 35.4 290.76, 86.17 -67.45, -37.73 in-out in 9.482 Saltbr-out 4.139 HRD-in -65.82, -56.46 69.69, -0.35 out-in-out SNCoio in-out ActLoopNT-in 2.958 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -131.28, 159.93 APE9-dihe-na 142.02, 171.32 APE8-dihe-in -81.41, 117.57 APE8-rot-out 188.89 APE67-dihe-in -62.69, -24.82 -43.74, -50.05 APE12-dist-in 7.634 APE11-dist-in 11.009 APE10-dist-in 5.294 APE9-dist-in 3.232 C121S,C181S,C333S TPO221 TPO221 XRAY 2.838 0.214 0.244 A 328 315 0 0 0 0 [[66, 317]] 1.0 8r4q CAMK_SIK3_HUMAN CAMK 1.8e-96 328.4 1 256 256 205 206 207 209 211 95 113 117 185 187 186 188 245 232 227 226 225 224 223 222 221 143 Serine/threonine-protein kinase SIK3
CAMK SIK3 SIK3_HUMAN 8R4QC Q9Y2K2 62 384 1321.0 DB8:401 Type1 Inactive DFGin 6.293 14.764 BLAminus -135.25, 170.61 66.71, 84.0 -99.07, 36.48 291.2, 85.91 -69.03, -37.82 in-out in 9.499 Saltbr-out 4.06 HRD-in -75.57, -57.14 68.81, -4.17 out-in-out SNCoio in-out ActLoopNT-in 2.89 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -129.57, 158.49 APE9-dihe-na 142.55, 170.52 APE8-dihe-in -81.5, 119.22 APE8-rot-out 55.54 APE67-dihe-in -62.66, -24.97 -44.86, -49.85 APE12-dist-in 7.616 APE11-dist-in 10.986 APE10-dist-in 5.263 APE9-dist-in 3.238 C121S,C181S,C333S TPO221 TPO221 XRAY 2.838 0.214 0.244 C 328 315 0 0 0 0 [[66, 317]] 1.0 8r4q CAMK_SIK3_HUMAN CAMK 1.8e-96 328.4 1 256 256 205 206 207 209 211 95 113 117 185 187 186 188 245 232 227 226 225 224 223 222 221 143 Serine/threonine-protein kinase SIK3
CAMK SIK3 SIK3_HUMAN 8R4QE Q9Y2K2 62 384 1321.0 DB8:401 Type1 Inactive DFGin 6.31 14.801 BLAminus -139.98, 171.19 65.46, 83.84 -99.17, 35.86 291.35, 86.11 -68.1, -36.3 in-out in 9.532 Saltbr-out 4.096 HRD-in -73.14, -51.55 63.42, 1.74 out-in-out SNCoio in-out ActLoopNT-in 3.101 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -130.33, 159.33 APE9-dihe-na 142.87, 171.07 APE8-dihe-in -80.24, 117.39 APE8-rot-out 190.21 APE67-dihe-in -61.05, -42.7 -42.39, -51.02 APE12-dist-in 7.543 APE11-dist-in 10.939 APE10-dist-in 5.259 APE9-dist-in 3.332 C121S,C181S,C333S TPO221 TPO221 XRAY 2.838 0.214 0.244 E 328 315 0 0 0 0 [[66, 317]] 1.0 8r4q CAMK_SIK3_HUMAN CAMK 1.8e-96 328.4 1 256 256 205 206 207 209 211 95 113 117 185 187 186 188 245 232 227 226 225 224 223 222 221 143 Serine/threonine-protein kinase SIK3
CAMK SIK3 SIK3_HUMAN 8R4QG Q9Y2K2 62 384 1321.0 DB8:401 Type1 Inactive DFGin 6.382 14.787 BLAminus -136.43, 170.69 66.72, 83.62 -98.78, 33.02 291.62, 86.44 -67.7, -37.12 in-out in 9.555 Saltbr-out 3.974 HRD-in -68.39, -50.34 62.72, 11.29 out-in-out SNCoio in-out ActLoopNT-in 2.925 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.11, 159.76 APE9-dihe-na 140.64, 172.45 APE8-dihe-in -81.58, 117.44 APE8-rot-out 189.92 APE67-dihe-in -60.6, -25.5 -43.58, -51.63 APE12-dist-in 7.433 APE11-dist-in 10.791 APE10-dist-in 5.137 APE9-dist-in 3.243 C121S,C181S,C333S TPO221 TPO221 XRAY 2.838 0.214 0.244 G 328 320 0 0 0 0 [[66, 317]] 1.0 8r4q CAMK_SIK3_HUMAN CAMK 1.8e-96 328.4 1 256 256 205 206 207 209 211 95 113 117 185 187 186 188 245 232 227 226 225 224 223 222 221 143 Serine/threonine-protein kinase SIK3
CAMK SIK3 SIK3_HUMAN 8R4QI Q9Y2K2 62 384 1321.0 DB8:401 Type1 Inactive DFGin 6.29 14.857 BLAminus -140.96, 171.42 64.9, 84.12 -97.96, 35.72 290.26, 86.39 -67.95, -38.18 in-out in 9.544 Saltbr-out 4.083 HRD-in -66.19, -52.55 62.88, 16.03 out-in-out SNCoio in-out ActLoopNT-in 2.935 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -130.02, 158.46 APE9-dihe-na 144.09, 168.25 APE8-dihe-in -80.55, 117.37 APE8-rot-out 188.41 APE67-dihe-in -62.44, -25.32 -44.55, -49.34 APE12-dist-in 7.633 APE11-dist-in 10.97 APE10-dist-in 5.248 APE9-dist-in 3.292 C121S,C181S,C333S TPO221 TPO221 XRAY 2.838 0.214 0.244 I 328 316 0 0 0 0 [[66, 317]] 1.0 8r4q CAMK_SIK3_HUMAN CAMK 1.8e-96 328.4 1 256 256 205 206 207 209 211 95 113 117 185 187 186 188 245 232 227 226 225 224 223 222 221 143 Serine/threonine-protein kinase SIK3
CAMK SIK3 SIK3_HUMAN 8R4QK Q9Y2K2 62 384 1321.0 DB8:401 Type1 Inactive DFGin 6.303 14.862 BLAminus -130.99, 169.6 63.77, 94.11 -108.55, 39.14 294.05, 89.24 -69.02, -37.64 in-out in 9.921 Saltbr-out 5.202 HRD-in -62.64, -54.81 63.03, 15.84 out-in-out SNCoio in-out ActLoopNT-in 2.983 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -127.45, 159.5 APE9-dihe-na 141.76, 170.37 APE8-dihe-in -80.52, 118.54 APE8-rot-out 187.31 APE67-dihe-in -62.28, -24.73 -43.25, -51.12 APE12-dist-in 7.521 APE11-dist-in 10.96 APE10-dist-in 5.223 APE9-dist-in 3.254 C121S,C181S,C333S TPO221 TPO221 XRAY 2.838 0.214 0.244 K 328 318 0 0 0 0 [[66, 317]] 1.0 8r4q CAMK_SIK3_HUMAN CAMK 1.8e-96 328.4 1 256 256 205 206 207 209 211 95 113 117 185 187 186 188 245 232 227 226 225 224 223 222 221 143 Serine/threonine-protein kinase SIK3

PDB: 8R4Q — CAMK SIK3_HUMAN

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 100.0% 8R4QA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK SIK3 SIK3_HUMAN 8R4QA Q9Y2K2 62 384 1321.0 DB8:401 Type1 Inactive DFGin 6.27 14.887 BLAminus -139.01, 171.07 65.51, 84.49 -98.95, 35.4 290.76, 86.17 -67.45, -37.73 in-out in 9.482 Saltbr-out 4.139 HRD-in -65.82, -56.46 69.69, -0.35 out-in-out SNCoio in-out ActLoopNT-in 2.958 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -131.28, 159.93 APE9-dihe-na 142.02, 171.32 APE8-dihe-in -81.41, 117.57 APE8-rot-out 188.89 APE67-dihe-in -62.69, -24.82 -43.74, -50.05 APE12-dist-in 7.634 APE11-dist-in 11.009 APE10-dist-in 5.294 APE9-dist-in 3.232 C121S,C181S,C333S TPO221 TPO221 XRAY 2.838 0.214 0.244 A 328 315 0 0 0 0 [[66, 317]] 1.0 8r4q Homo sapiens CAMK_SIK3_HUMAN CAMK 1.8e-96 328.4 1 256 256 205 206 207 209 211 95 113 117 185 187 186 188 245 232 227 226 225 224 223 222 221 143 Serine/threonine-protein kinase SIK3
CAMK SIK3 SIK3_HUMAN 8R4QC Q9Y2K2 62 384 1321.0 DB8:401 Type1 Inactive DFGin 6.293 14.764 BLAminus -135.25, 170.61 66.71, 84.0 -99.07, 36.48 291.2, 85.91 -69.03, -37.82 in-out in 9.499 Saltbr-out 4.06 HRD-in -75.57, -57.14 68.81, -4.17 out-in-out SNCoio in-out ActLoopNT-in 2.89 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -129.57, 158.49 APE9-dihe-na 142.55, 170.52 APE8-dihe-in -81.5, 119.22 APE8-rot-out 55.54 APE67-dihe-in -62.66, -24.97 -44.86, -49.85 APE12-dist-in 7.616 APE11-dist-in 10.986 APE10-dist-in 5.263 APE9-dist-in 3.238 C121S,C181S,C333S TPO221 TPO221 XRAY 2.838 0.214 0.244 C 328 315 0 0 0 0 [[66, 317]] 1.0 8r4q Homo sapiens CAMK_SIK3_HUMAN CAMK 1.8e-96 328.4 1 256 256 205 206 207 209 211 95 113 117 185 187 186 188 245 232 227 226 225 224 223 222 221 143 Serine/threonine-protein kinase SIK3
CAMK SIK3 SIK3_HUMAN 8R4QE Q9Y2K2 62 384 1321.0 DB8:401 Type1 Inactive DFGin 6.31 14.801 BLAminus -139.98, 171.19 65.46, 83.84 -99.17, 35.86 291.35, 86.11 -68.1, -36.3 in-out in 9.532 Saltbr-out 4.096 HRD-in -73.14, -51.55 63.42, 1.74 out-in-out SNCoio in-out ActLoopNT-in 3.101 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -130.33, 159.33 APE9-dihe-na 142.87, 171.07 APE8-dihe-in -80.24, 117.39 APE8-rot-out 190.21 APE67-dihe-in -61.05, -42.7 -42.39, -51.02 APE12-dist-in 7.543 APE11-dist-in 10.939 APE10-dist-in 5.259 APE9-dist-in 3.332 C121S,C181S,C333S TPO221 TPO221 XRAY 2.838 0.214 0.244 E 328 315 0 0 0 0 [[66, 317]] 1.0 8r4q Homo sapiens CAMK_SIK3_HUMAN CAMK 1.8e-96 328.4 1 256 256 205 206 207 209 211 95 113 117 185 187 186 188 245 232 227 226 225 224 223 222 221 143 Serine/threonine-protein kinase SIK3
CAMK SIK3 SIK3_HUMAN 8R4QG Q9Y2K2 62 384 1321.0 DB8:401 Type1 Inactive DFGin 6.382 14.787 BLAminus -136.43, 170.69 66.72, 83.62 -98.78, 33.02 291.62, 86.44 -67.7, -37.12 in-out in 9.555 Saltbr-out 3.974 HRD-in -68.39, -50.34 62.72, 11.29 out-in-out SNCoio in-out ActLoopNT-in 2.925 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.11, 159.76 APE9-dihe-na 140.64, 172.45 APE8-dihe-in -81.58, 117.44 APE8-rot-out 189.92 APE67-dihe-in -60.6, -25.5 -43.58, -51.63 APE12-dist-in 7.433 APE11-dist-in 10.791 APE10-dist-in 5.137 APE9-dist-in 3.243 C121S,C181S,C333S TPO221 TPO221 XRAY 2.838 0.214 0.244 G 328 320 0 0 0 0 [[66, 317]] 1.0 8r4q Homo sapiens CAMK_SIK3_HUMAN CAMK 1.8e-96 328.4 1 256 256 205 206 207 209 211 95 113 117 185 187 186 188 245 232 227 226 225 224 223 222 221 143 Serine/threonine-protein kinase SIK3
CAMK SIK3 SIK3_HUMAN 8R4QI Q9Y2K2 62 384 1321.0 DB8:401 Type1 Inactive DFGin 6.29 14.857 BLAminus -140.96, 171.42 64.9, 84.12 -97.96, 35.72 290.26, 86.39 -67.95, -38.18 in-out in 9.544 Saltbr-out 4.083 HRD-in -66.19, -52.55 62.88, 16.03 out-in-out SNCoio in-out ActLoopNT-in 2.935 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -130.02, 158.46 APE9-dihe-na 144.09, 168.25 APE8-dihe-in -80.55, 117.37 APE8-rot-out 188.41 APE67-dihe-in -62.44, -25.32 -44.55, -49.34 APE12-dist-in 7.633 APE11-dist-in 10.97 APE10-dist-in 5.248 APE9-dist-in 3.292 C121S,C181S,C333S TPO221 TPO221 XRAY 2.838 0.214 0.244 I 328 316 0 0 0 0 [[66, 317]] 1.0 8r4q Homo sapiens CAMK_SIK3_HUMAN CAMK 1.8e-96 328.4 1 256 256 205 206 207 209 211 95 113 117 185 187 186 188 245 232 227 226 225 224 223 222 221 143 Serine/threonine-protein kinase SIK3
CAMK SIK3 SIK3_HUMAN 8R4QK Q9Y2K2 62 384 1321.0 DB8:401 Type1 Inactive DFGin 6.303 14.862 BLAminus -130.99, 169.6 63.77, 94.11 -108.55, 39.14 294.05, 89.24 -69.02, -37.64 in-out in 9.921 Saltbr-out 5.202 HRD-in -62.64, -54.81 63.03, 15.84 out-in-out SNCoio in-out ActLoopNT-in 2.983 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -127.45, 159.5 APE9-dihe-na 141.76, 170.37 APE8-dihe-in -80.52, 118.54 APE8-rot-out 187.31 APE67-dihe-in -62.28, -24.73 -43.25, -51.12 APE12-dist-in 7.521 APE11-dist-in 10.96 APE10-dist-in 5.223 APE9-dist-in 3.254 C121S,C181S,C333S TPO221 TPO221 XRAY 2.838 0.214 0.244 K 328 318 0 0 0 0 [[66, 317]] 1.0 8r4q Homo sapiens CAMK_SIK3_HUMAN CAMK 1.8e-96 328.4 1 256 256 205 206 207 209 211 95 113 117 185 187 186 188 245 232 227 226 225 224 223 222 221 143 Serine/threonine-protein kinase SIK3

PDB: 8R4Q — CAMK SIK3_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name