| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMK | SIK3 | SIK3_HUMAN | 8R4OA | Q9Y2K2 | 62 | 384 | 1321.0 | XVI:401 | Type1 | Inactive | DFGin | 6.7893 | 14.5188 | BLAminus | -125.71, 175.86 | 61.17, 85.12 | -103.12, 32.38 | 284.88, 82.02 | -69.13, -38.43 | in-in | in | 9.2107 | Saltbr-in | 2.7071 | HRD-in | -68.78, -49.07 | 59.21, 16.18 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.9696 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -137.95, 164.22 | APE9-dihe-na | 138.1, 167.3 | APE8-dihe-in | -77.26, 120.01 | APE8-rot-out | 188.49 | APE67-dihe-in | -63.99, -17.85 | -45.41, -48.19 | APE12-dist-in | 7.6133 | APE11-dist-in | 11.0803 | APE10-dist-in | 5.4608 | APE9-dist-in | 3.3384 | C121S,C181S,C333S | TPO221 | TPO221 | XRAY | 2.725 | 0.216 | 0.244 | A | 328.0 | 316.0 | 0 | 27 | 27 | 0 | [[66, 317]] | 1.0 | 8r4o | CAMK_SIK3_HUMAN | CAMK | 1.8e-96 | 328.4 | 1.0 | 256.0 | 256.0 | 205 | 206 | 207 | 209 | 211 | 95 | 113 | 117 | 185 | 187 | 186 | 188.0 | 245 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 143 | Serine/threonine-protein kinase SIK3 |
| CAMK | SIK3 | SIK3_HUMAN | 8R4OC | Q9Y2K2 | 62 | 384 | 1321.0 | XVI:401 | Type1 | Inactive | DFGin | 6.8282 | 14.4465 | BLAminus | -129.55, 168.82 | 71.42, 83.09 | -102.43, 31.89 | 286.31, 82.55 | -67.62, -40.46 | in-in | in | 9.1654 | Saltbr-in | 2.6441 | HRD-in | -65.95, -51.63 | 61.3, 16.73 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.9607 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -137.01, 164.27 | APE9-dihe-na | 137.9, 165.52 | APE8-dihe-in | -76.91, 120.34 | APE8-rot-out | 188.4 | APE67-dihe-in | -64.71, -17.77 | -46.15, -47.73 | APE12-dist-in | 7.5906 | APE11-dist-in | 11.054 | APE10-dist-in | 5.4419 | APE9-dist-in | 3.3689 | C121S,C181S,C333S | TPO221 | TPO221 | XRAY | 2.725 | 0.216 | 0.244 | C | 328.0 | 315.0 | 0 | 27 | 27 | 0 | [[66, 317]] | 1.0 | 8r4o | CAMK_SIK3_HUMAN | CAMK | 1.8e-96 | 328.4 | 1.0 | 256.0 | 256.0 | 205 | 206 | 207 | 209 | 211 | 95 | 113 | 117 | 185 | 187 | 186 | 188.0 | 245 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 143 | Serine/threonine-protein kinase SIK3 |
| CAMK | SIK3 | SIK3_HUMAN | 8R4OE | Q9Y2K2 | 62 | 384 | 1321.0 | XVI:401 | Type1 | Inactive | DFGin | 6.9385 | 14.5972 | BLAminus | -125.14, 175.42 | 62.75, 84.83 | -103.08, 31.64 | 285.5, 81.52 | -67.98, -40.19 | in-in | in | 9.1211 | Saltbr-in | 2.6363 | HRD-in | -67.61, -51.56 | 60.74, 18.57 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.9839 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -137.89, 164.3 | APE9-dihe-na | 136.57, 164.66 | APE8-dihe-in | -75.86, 119.82 | APE8-rot-out | 188.72 | APE67-dihe-in | -65.37, -17.85 | -45.28, -48.13 | APE12-dist-in | 7.5804 | APE11-dist-in | 11.0615 | APE10-dist-in | 5.4579 | APE9-dist-in | 3.3905 | C121S,C181S,C333S | TPO221 | TPO221 | XRAY | 2.725 | 0.216 | 0.244 | E | 328.0 | 315.0 | 0 | 27 | 27 | 0 | [[66, 317]] | 1.0 | 8r4o | CAMK_SIK3_HUMAN | CAMK | 1.8e-96 | 328.4 | 1.0 | 256.0 | 256.0 | 205 | 206 | 207 | 209 | 211 | 95 | 113 | 117 | 185 | 187 | 186 | 188.0 | 245 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 143 | Serine/threonine-protein kinase SIK3 |
| CAMK | SIK3 | SIK3_HUMAN | 8R4OG | Q9Y2K2 | 62 | 384 | 1321.0 | XVI:401 | Type1 | Inactive | DFGin | 6.9095 | 14.6146 | BLAminus | -124.38, 176.33 | 61.69, 84.93 | -103.28, 30.5 | 286.01, 80.88 | -68.19, -39.92 | in-in | in | 9.1822 | Saltbr-in | 2.8664 | HRD-in | -70.7, -46.33 | 56.28, 19.08 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.9815 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -137.89, 164.45 | APE9-dihe-na | 136.64, 161.97 | APE8-dihe-in | -75.05, 120.57 | APE8-rot-out | 189.09 | APE67-dihe-in | -63.53, -18.35 | -45.81, -48.67 | APE12-dist-in | 7.5201 | APE11-dist-in | 11.0215 | APE10-dist-in | 5.4497 | APE9-dist-in | 3.3949 | C121S,C181S,C333S | TPO221 | TPO221 | XRAY | 2.725 | 0.216 | 0.244 | G | 328.0 | 323.0 | 0 | 27 | 27 | 0 | [[66, 317]] | 1.0 | 8r4o | CAMK_SIK3_HUMAN | CAMK | 1.8e-96 | 328.4 | 1.0 | 256.0 | 256.0 | 205 | 206 | 207 | 209 | 211 | 95 | 113 | 117 | 185 | 187 | 186 | 188.0 | 245 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 143 | Serine/threonine-protein kinase SIK3 |
| CAMK | SIK3 | SIK3_HUMAN | 8R4OI | Q9Y2K2 | 62 | 384 | 1321.0 | XVI:401 | Type1 | Inactive | DFGin | 6.8991 | 14.5651 | BLAminus | -132.68, 177.0 | 60.73, 84.44 | -102.51, 32.39 | 285.22, 81.32 | -69.52, -27.66 | in-in | in | 9.1945 | Saltbr-in | 2.7141 | HRD-in | -82.53, -49.17 | 62.06, 18.27 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.9594 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -137.98, 164.61 | APE9-dihe-na | 136.93, 163.75 | APE8-dihe-in | -76.2, 120.78 | APE8-rot-out | 188.08 | APE67-dihe-in | -64.67, -17.51 | -46.63, -48.17 | APE12-dist-in | 7.5868 | APE11-dist-in | 11.0794 | APE10-dist-in | 5.4714 | APE9-dist-in | 3.3811 | C121S,C181S,C333S | TPO221 | TPO221 | XRAY | 2.725 | 0.216 | 0.244 | I | 328.0 | 317.0 | 0 | 27 | 27 | 0 | [[66, 317]] | 1.0 | 8r4o | CAMK_SIK3_HUMAN | CAMK | 1.8e-96 | 328.4 | 1.0 | 256.0 | 256.0 | 205 | 206 | 207 | 209 | 211 | 95 | 113 | 117 | 185 | 187 | 186 | 188.0 | 245 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 143 | Serine/threonine-protein kinase SIK3 |
| CAMK | SIK3 | SIK3_HUMAN | 8R4OK | Q9Y2K2 | 62 | 384 | 1321.0 | XVI:401 | Type1 | Inactive | DFGin | 6.9732 | 14.7833 | BLAminus | -128.99, 172.89 | 59.57, 78.9 | -97.11, 33.89 | 284.36, 89.39 | -70.96, -33.22 | in-in | in | 9.2122 | Saltbr-in | 2.7328 | HRD-in | -72.38, -44.94 | 53.52, 24.05 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.0043 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -139.55, 165.44 | APE9-dihe-na | 135.73, 162.63 | APE8-dihe-in | -74.63, 117.97 | APE8-rot-out | 178.94 | APE67-dihe-in | -64.29, -16.62 | -46.32, -48.14 | APE12-dist-in | 7.4101 | APE11-dist-in | 10.9261 | APE10-dist-in | 5.3919 | APE9-dist-in | 3.2952 | C121S,C181S,C333S | TPO221 | TPO221 | XRAY | 2.725 | 0.216 | 0.244 | K | 328.0 | 316.0 | 0 | 27 | 27 | 0 | [[66, 317]] | 1.0 | 8r4o | CAMK_SIK3_HUMAN | CAMK | 1.8e-96 | 328.4 | 1.0 | 256.0 | 256.0 | 205 | 206 | 207 | 209 | 211 | 95 | 113 | 117 | 185 | 187 | 186 | 188.0 | 245 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 143 | Serine/threonine-protein kinase SIK3 |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMK | SIK3 | SIK3_HUMAN | 8R4OA | Q9Y2K2 | 62 | 384 | 1321.0 | XVI:401 | Type1 | Inactive | DFGin | 6.7893 | 14.5188 | BLAminus | -125.71, 175.86 | 61.17, 85.12 | -103.12, 32.38 | 284.88, 82.02 | -69.13, -38.43 | in-in | in | 9.2107 | Saltbr-in | 2.7071 | HRD-in | -68.78, -49.07 | 59.21, 16.18 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.9696 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -137.95, 164.22 | APE9-dihe-na | 138.1, 167.3 | APE8-dihe-in | -77.26, 120.01 | APE8-rot-out | 188.49 | APE67-dihe-in | -63.99, -17.85 | -45.41, -48.19 | APE12-dist-in | 7.6133 | APE11-dist-in | 11.0803 | APE10-dist-in | 5.4608 | APE9-dist-in | 3.3384 | C121S,C181S,C333S | TPO221 | TPO221 | XRAY | 2.725 | 0.216 | 0.244 | A | 328.0 | 316.0 | 0 | 27 | 27 | 0 | [[66, 317]] | 1.0 | 8r4o | Homo sapiens | CAMK_SIK3_HUMAN | CAMK | 1.8e-96 | 328.4 | 1.0 | 256.0 | 256.0 | 205 | 206 | 207 | 209 | 211 | 95 | 113 | 117 | 185 | 187 | 186 | 188.0 | 245 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 143 | Serine/threonine-protein kinase SIK3 |
| CAMK | SIK3 | SIK3_HUMAN | 8R4OC | Q9Y2K2 | 62 | 384 | 1321.0 | XVI:401 | Type1 | Inactive | DFGin | 6.8282 | 14.4465 | BLAminus | -129.55, 168.82 | 71.42, 83.09 | -102.43, 31.89 | 286.31, 82.55 | -67.62, -40.46 | in-in | in | 9.1654 | Saltbr-in | 2.6441 | HRD-in | -65.95, -51.63 | 61.3, 16.73 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.9607 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -137.01, 164.27 | APE9-dihe-na | 137.9, 165.52 | APE8-dihe-in | -76.91, 120.34 | APE8-rot-out | 188.4 | APE67-dihe-in | -64.71, -17.77 | -46.15, -47.73 | APE12-dist-in | 7.5906 | APE11-dist-in | 11.054 | APE10-dist-in | 5.4419 | APE9-dist-in | 3.3689 | C121S,C181S,C333S | TPO221 | TPO221 | XRAY | 2.725 | 0.216 | 0.244 | C | 328.0 | 315.0 | 0 | 27 | 27 | 0 | [[66, 317]] | 1.0 | 8r4o | Homo sapiens | CAMK_SIK3_HUMAN | CAMK | 1.8e-96 | 328.4 | 1.0 | 256.0 | 256.0 | 205 | 206 | 207 | 209 | 211 | 95 | 113 | 117 | 185 | 187 | 186 | 188.0 | 245 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 143 | Serine/threonine-protein kinase SIK3 |
| CAMK | SIK3 | SIK3_HUMAN | 8R4OE | Q9Y2K2 | 62 | 384 | 1321.0 | XVI:401 | Type1 | Inactive | DFGin | 6.9385 | 14.5972 | BLAminus | -125.14, 175.42 | 62.75, 84.83 | -103.08, 31.64 | 285.5, 81.52 | -67.98, -40.19 | in-in | in | 9.1211 | Saltbr-in | 2.6363 | HRD-in | -67.61, -51.56 | 60.74, 18.57 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.9839 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -137.89, 164.3 | APE9-dihe-na | 136.57, 164.66 | APE8-dihe-in | -75.86, 119.82 | APE8-rot-out | 188.72 | APE67-dihe-in | -65.37, -17.85 | -45.28, -48.13 | APE12-dist-in | 7.5804 | APE11-dist-in | 11.0615 | APE10-dist-in | 5.4579 | APE9-dist-in | 3.3905 | C121S,C181S,C333S | TPO221 | TPO221 | XRAY | 2.725 | 0.216 | 0.244 | E | 328.0 | 315.0 | 0 | 27 | 27 | 0 | [[66, 317]] | 1.0 | 8r4o | Homo sapiens | CAMK_SIK3_HUMAN | CAMK | 1.8e-96 | 328.4 | 1.0 | 256.0 | 256.0 | 205 | 206 | 207 | 209 | 211 | 95 | 113 | 117 | 185 | 187 | 186 | 188.0 | 245 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 143 | Serine/threonine-protein kinase SIK3 |
| CAMK | SIK3 | SIK3_HUMAN | 8R4OG | Q9Y2K2 | 62 | 384 | 1321.0 | XVI:401 | Type1 | Inactive | DFGin | 6.9095 | 14.6146 | BLAminus | -124.38, 176.33 | 61.69, 84.93 | -103.28, 30.5 | 286.01, 80.88 | -68.19, -39.92 | in-in | in | 9.1822 | Saltbr-in | 2.8664 | HRD-in | -70.7, -46.33 | 56.28, 19.08 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.9815 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -137.89, 164.45 | APE9-dihe-na | 136.64, 161.97 | APE8-dihe-in | -75.05, 120.57 | APE8-rot-out | 189.09 | APE67-dihe-in | -63.53, -18.35 | -45.81, -48.67 | APE12-dist-in | 7.5201 | APE11-dist-in | 11.0215 | APE10-dist-in | 5.4497 | APE9-dist-in | 3.3949 | C121S,C181S,C333S | TPO221 | TPO221 | XRAY | 2.725 | 0.216 | 0.244 | G | 328.0 | 323.0 | 0 | 27 | 27 | 0 | [[66, 317]] | 1.0 | 8r4o | Homo sapiens | CAMK_SIK3_HUMAN | CAMK | 1.8e-96 | 328.4 | 1.0 | 256.0 | 256.0 | 205 | 206 | 207 | 209 | 211 | 95 | 113 | 117 | 185 | 187 | 186 | 188.0 | 245 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 143 | Serine/threonine-protein kinase SIK3 |
| CAMK | SIK3 | SIK3_HUMAN | 8R4OI | Q9Y2K2 | 62 | 384 | 1321.0 | XVI:401 | Type1 | Inactive | DFGin | 6.8991 | 14.5651 | BLAminus | -132.68, 177.0 | 60.73, 84.44 | -102.51, 32.39 | 285.22, 81.32 | -69.52, -27.66 | in-in | in | 9.1945 | Saltbr-in | 2.7141 | HRD-in | -82.53, -49.17 | 62.06, 18.27 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.9594 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -137.98, 164.61 | APE9-dihe-na | 136.93, 163.75 | APE8-dihe-in | -76.2, 120.78 | APE8-rot-out | 188.08 | APE67-dihe-in | -64.67, -17.51 | -46.63, -48.17 | APE12-dist-in | 7.5868 | APE11-dist-in | 11.0794 | APE10-dist-in | 5.4714 | APE9-dist-in | 3.3811 | C121S,C181S,C333S | TPO221 | TPO221 | XRAY | 2.725 | 0.216 | 0.244 | I | 328.0 | 317.0 | 0 | 27 | 27 | 0 | [[66, 317]] | 1.0 | 8r4o | Homo sapiens | CAMK_SIK3_HUMAN | CAMK | 1.8e-96 | 328.4 | 1.0 | 256.0 | 256.0 | 205 | 206 | 207 | 209 | 211 | 95 | 113 | 117 | 185 | 187 | 186 | 188.0 | 245 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 143 | Serine/threonine-protein kinase SIK3 |
| CAMK | SIK3 | SIK3_HUMAN | 8R4OK | Q9Y2K2 | 62 | 384 | 1321.0 | XVI:401 | Type1 | Inactive | DFGin | 6.9732 | 14.7833 | BLAminus | -128.99, 172.89 | 59.57, 78.9 | -97.11, 33.89 | 284.36, 89.39 | -70.96, -33.22 | in-in | in | 9.2122 | Saltbr-in | 2.7328 | HRD-in | -72.38, -44.94 | 53.52, 24.05 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.0043 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -139.55, 165.44 | APE9-dihe-na | 135.73, 162.63 | APE8-dihe-in | -74.63, 117.97 | APE8-rot-out | 178.94 | APE67-dihe-in | -64.29, -16.62 | -46.32, -48.14 | APE12-dist-in | 7.4101 | APE11-dist-in | 10.9261 | APE10-dist-in | 5.3919 | APE9-dist-in | 3.2952 | C121S,C181S,C333S | TPO221 | TPO221 | XRAY | 2.725 | 0.216 | 0.244 | K | 328.0 | 316.0 | 0 | 27 | 27 | 0 | [[66, 317]] | 1.0 | 8r4o | Homo sapiens | CAMK_SIK3_HUMAN | CAMK | 1.8e-96 | 328.4 | 1.0 | 256.0 | 256.0 | 205 | 206 | 207 | 209 | 211 | 95 | 113 | 117 | 185 | 187 | 186 | 188.0 | 245 | 232 | 227 | 226 | 225 | 224 | 223 | 222 | 221 | 143 | Serine/threonine-protein kinase SIK3 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
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