PDB: 8PQG — TYR KIT_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8PQGC

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 8PQGA P10721 566 931 976.0 9JI:61001 Type1 Active DFGin 7.0429 14.1671 BLAminus -124.55, -174.12 54.99, 78.46 -96.45, 26.87 280.71, 70.71 -64.48, -33.68 in-in in 8.0418 Saltbr-in 2.847 HRD-in -90.54, -41.04 71.94, -5.78 in-in-in SNCiii in-in ActLoopNT-in 3.0249 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -64.66, 135.23 APE9-dihe-in -115.63, 149.54 APE8-dihe-in -83.89, 83.11 APE8-rot-na 25.85 APE67-dihe-in -70.62, -11.93 -61.47, -41.45 APE12-dist-na 999.0 APE11-dist-na 9.8657 APE10-dist-na 13.0316 APE9-dist-in 7.6588 I563S,V569S,Y609Q,L631S,M651E,I662H,T670I,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.4 0.207 0.231 A 327.0 283.0 5 30 25 5 [[589, 926]] 1.0 8pqg TYR_KIT_HUMAN TYR 4.7e-104 353.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQGC P10721 565 932 976.0 9JI:61001 Type1 Active DFGin 6.9981 13.7774 BLAminus -125.01, -177.18 59.69, 81.81 -99.94, 28.85 284.0, 66.15 -68.84, -20.03 in-in in 7.8376 Saltbr-in 2.8929 HRD-in -87.34, -47.72 75.4, 1.14 in-in-in SNCiii in-in ActLoopNT-in 2.9945 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -62.89, 137.72 APE9-dihe-in -124.07, 148.98 APE8-dihe-in -81.48, 76.95 APE8-rot-na 33.1 APE67-dihe-in -72.2, -11.85 -56.44, -41.57 APE12-dist-na 14.3671 APE11-dist-na 10.0194 APE10-dist-na 12.9788 APE9-dist-in 7.6471 I563S,V569S,Y609Q,L631S,M651E,I662H,T670I,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.4 0.207 0.231 C 327.0 290.0 0 30 30 0 [[589, 926]] 1.0 8pqg TYR_KIT_HUMAN TYR 4.7e-104 353.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

PDB: 8PQG — TYR KIT_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8PQGC

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 8PQGA P10721 566 931 976.0 9JI:61001 Type1 Active DFGin 7.0429 14.1671 BLAminus -124.55, -174.12 54.99, 78.46 -96.45, 26.87 280.71, 70.71 -64.48, -33.68 in-in in 8.0418 Saltbr-in 2.847 HRD-in -90.54, -41.04 71.94, -5.78 in-in-in SNCiii in-in ActLoopNT-in 3.0249 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -64.66, 135.23 APE9-dihe-in -115.63, 149.54 APE8-dihe-in -83.89, 83.11 APE8-rot-na 25.85 APE67-dihe-in -70.62, -11.93 -61.47, -41.45 APE12-dist-na 999.0 APE11-dist-na 9.8657 APE10-dist-na 13.0316 APE9-dist-in 7.6588 I563S,V569S,Y609Q,L631S,M651E,I662H,T670I,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.4 0.207 0.231 A 327.0 283.0 5 30 25 5 [[589, 926]] 1.0 8pqg Homo sapiens TYR_KIT_HUMAN TYR 4.7e-104 353.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQGC P10721 565 932 976.0 9JI:61001 Type1 Active DFGin 6.9981 13.7774 BLAminus -125.01, -177.18 59.69, 81.81 -99.94, 28.85 284.0, 66.15 -68.84, -20.03 in-in in 7.8376 Saltbr-in 2.8929 HRD-in -87.34, -47.72 75.4, 1.14 in-in-in SNCiii in-in ActLoopNT-in 2.9945 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -62.89, 137.72 APE9-dihe-in -124.07, 148.98 APE8-dihe-in -81.48, 76.95 APE8-rot-na 33.1 APE67-dihe-in -72.2, -11.85 -56.44, -41.57 APE12-dist-na 14.3671 APE11-dist-na 10.0194 APE10-dist-na 12.9788 APE9-dist-in 7.6471 I563S,V569S,Y609Q,L631S,M651E,I662H,T670I,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.4 0.207 0.231 C 327.0 290.0 0 30 30 0 [[589, 926]] 1.0 8pqg Homo sapiens TYR_KIT_HUMAN TYR 4.7e-104 353.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

PDB: 8PQG — TYR KIT_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name