PDB: 8F1W — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 4 100.0% 8F1WA
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 8F1WA P00533 701 1007 1210.0 R2E:1101 Type1 Inactive DFGin 5.28 16.379 BLBtrans -128.45, -172.46 54.26, 51.11 -103.7, 148.5 152.13, 74.45 76.8, -16.65 out-out out 13.469 Saltbr-out 13.206 HRD-in -72.99, -57.24 80.64, -5.91 out-out-out SNCooo out-out ActLoopNT-out 8.08 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -99.43, -53.06 APE9-dihe-in -72.87, 140.92 APE8-dihe-in -84.73, 81.02 APE8-rot-na 32.64 APE67-dihe-in -74.93, -2.07 -61.05, -46.98 APE12-dist-na 19.316 APE11-dist-na 16.495 APE10-dist-na 12.256 APE9-dist-in 7.556 T790M,V948R None None XRAY 3.2 0.233 0.274 A 331 303 4 0 0 4 [[712, 970]] 1.0 8f1w TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8F1WB P00533 700 1007 1210.0 R2E:1101 Type1 Inactive DFGin 4.358 15.734 BLBtrans -129.99, -174.05 52.25, 52.37 -111.11, 152.05 129.92, 81.6 82.17, -3.69 out-out out 13.437 Saltbr-out 14.463 HRD-in -72.48, -56.45 81.7, -6.34 out-out-none SNCoon out-none ActLoopNT-out 8.913 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 140.67 APE8-dihe-in -84.49, 80.46 APE8-rot-na 32.73 APE67-dihe-in -74.43, -1.94 -61.83, -47.13 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.727 T790M,V948R None None XRAY 3.2 0.233 0.274 B 331 288 17 0 0 14 [[712, 970]] 1.0 8f1w TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8F1WC P00533 700 1007 1210.0 R2E:1101 Type1 Inactive DFGin 5.411 16.33 BLBtrans -128.1, -172.08 53.52, 45.92 -101.71, 133.48 161.59, 77.0 98.24, -6.72 out-out out 13.166 Saltbr-out 13.462 HRD-in -72.8, -56.41 81.38, -6.01 out-out-none SNCoon out-none ActLoopNT-out 8.716 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 141.55 APE8-dihe-in -84.21, 80.52 APE8-rot-na 32.64 APE67-dihe-in -74.76, -1.9 -61.65, -47.2 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.682 T790M,V948R None None XRAY 3.2 0.233 0.274 C 331 290 18 0 0 14 [[712, 970]] 1.0 8f1w TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8F1WD P00533 700 1007 1210.0 R2E:1101 Type1 Inactive DFGin 5.365 16.324 BLBtrans -129.36, -171.8 54.41, 47.64 -102.11, 148.89 154.19, 76.79 83.64, -7.92 out-out out 13.848 Saltbr-out 18.195 HRD-in -72.16, -56.36 81.51, -6.86 out-out-out SNCooo out-out ActLoopNT-out 8.707 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -108.09, -47.67 APE9-dihe-in -78.16, 141.77 APE8-dihe-in -84.0, 80.49 APE8-rot-na 32.67 APE67-dihe-in -74.57, -2.54 -61.13, -46.62 APE12-dist-na 18.773 APE11-dist-na 15.914 APE10-dist-na 11.838 APE9-dist-in 7.585 T790M,V948R None None XRAY 3.2 0.233 0.274 D 331 304 4 0 0 4 [[712, 970]] 1.0 8f1w TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 8F1W — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 4 100.0% 8F1WA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 8F1WA P00533 701 1007 1210.0 R2E:1101 Type1 Inactive DFGin 5.28 16.379 BLBtrans -128.45, -172.46 54.26, 51.11 -103.7, 148.5 152.13, 74.45 76.8, -16.65 out-out out 13.469 Saltbr-out 13.206 HRD-in -72.99, -57.24 80.64, -5.91 out-out-out SNCooo out-out ActLoopNT-out 8.08 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -99.43, -53.06 APE9-dihe-in -72.87, 140.92 APE8-dihe-in -84.73, 81.02 APE8-rot-na 32.64 APE67-dihe-in -74.93, -2.07 -61.05, -46.98 APE12-dist-na 19.316 APE11-dist-na 16.495 APE10-dist-na 12.256 APE9-dist-in 7.556 T790M,V948R None None XRAY 3.2 0.233 0.274 A 331 303 4 0 0 4 [[712, 970]] 1.0 8f1w Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8F1WB P00533 700 1007 1210.0 R2E:1101 Type1 Inactive DFGin 4.358 15.734 BLBtrans -129.99, -174.05 52.25, 52.37 -111.11, 152.05 129.92, 81.6 82.17, -3.69 out-out out 13.437 Saltbr-out 14.463 HRD-in -72.48, -56.45 81.7, -6.34 out-out-none SNCoon out-none ActLoopNT-out 8.913 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 140.67 APE8-dihe-in -84.49, 80.46 APE8-rot-na 32.73 APE67-dihe-in -74.43, -1.94 -61.83, -47.13 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.727 T790M,V948R None None XRAY 3.2 0.233 0.274 B 331 288 17 0 0 14 [[712, 970]] 1.0 8f1w Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8F1WC P00533 700 1007 1210.0 R2E:1101 Type1 Inactive DFGin 5.411 16.33 BLBtrans -128.1, -172.08 53.52, 45.92 -101.71, 133.48 161.59, 77.0 98.24, -6.72 out-out out 13.166 Saltbr-out 13.462 HRD-in -72.8, -56.41 81.38, -6.01 out-out-none SNCoon out-none ActLoopNT-out 8.716 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 141.55 APE8-dihe-in -84.21, 80.52 APE8-rot-na 32.64 APE67-dihe-in -74.76, -1.9 -61.65, -47.2 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.682 T790M,V948R None None XRAY 3.2 0.233 0.274 C 331 290 18 0 0 14 [[712, 970]] 1.0 8f1w Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8F1WD P00533 700 1007 1210.0 R2E:1101 Type1 Inactive DFGin 5.365 16.324 BLBtrans -129.36, -171.8 54.41, 47.64 -102.11, 148.89 154.19, 76.79 83.64, -7.92 out-out out 13.848 Saltbr-out 18.195 HRD-in -72.16, -56.36 81.51, -6.86 out-out-out SNCooo out-out ActLoopNT-out 8.707 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -108.09, -47.67 APE9-dihe-in -78.16, 141.77 APE8-dihe-in -84.0, 80.49 APE8-rot-na 32.67 APE67-dihe-in -74.57, -2.54 -61.13, -46.62 APE12-dist-na 18.773 APE11-dist-na 15.914 APE10-dist-na 11.838 APE9-dist-in 7.585 T790M,V948R None None XRAY 3.2 0.233 0.274 D 331 304 4 0 0 4 [[712, 970]] 1.0 8f1w Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 8F1W — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name