PDB: 8D73 — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8D73A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 8D73A P00533 703 1011 1210.0 QCR:1502 Type1.5_Back Active DFGin 5.3959 14.6386 BLAminus -137.39, -166.88 72.14, 68.63 -95.45, 13.53 294.58, 102.22 -51.07, -34.93 in-in in 8.4796 Saltbr-in 2.8987 HRD-in -72.18, -47.68 71.87, 13.91 in-in-in SNCiii in-in ActLoopNT-in 2.8463 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -94.59, 132.11 APE9-dihe-in -138.43, 150.74 APE8-dihe-in -80.34, 79.03 APE8-rot-na 34.01 APE67-dihe-in -74.66, -9.01 -47.69, -41.15 APE12-dist-na 12.5064 APE11-dist-na 11.236 APE10-dist-na 11.2771 APE9-dist-in 7.1391 T790M,L858R,V948R None None XRAY 2.17 0.196 0.285 A 348.0 309.0 0 30 30 0 [[712, 970]] 1.0 8d73 TYR_EGFR_HUMAN TYR 7.7e-87 296.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8D73B P00533 704 1012 1210.0 QCR:1502 Type1.5_Back Active DFGin 5.3954 14.6503 BLAminus -137.92, -166.35 72.18, 68.71 -94.69, 12.26 295.76, 102.32 -51.71, -34.28 in-in in 8.4456 Saltbr-in 2.9106 HRD-in -71.23, -48.01 72.11, 12.51 in-in-in SNCiii in-in ActLoopNT-in 2.8549 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -97.18, 131.42 APE9-dihe-in -139.31, 151.96 APE8-dihe-in -80.51, 78.64 APE8-rot-na 33.78 APE67-dihe-in -74.28, -9.24 -48.16, -40.87 APE12-dist-na 12.7008 APE11-dist-na 11.3639 APE10-dist-na 11.4097 APE9-dist-in 7.2216 T790M,L858R,V948R None None XRAY 2.17 0.196 0.285 B 348.0 309.0 0 30 30 0 [[712, 970]] 1.0 8d73 TYR_EGFR_HUMAN TYR 7.7e-87 296.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 8D73 — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8D73A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 8D73A P00533 703 1011 1210.0 QCR:1502 Type1.5_Back Active DFGin 5.3959 14.6386 BLAminus -137.39, -166.88 72.14, 68.63 -95.45, 13.53 294.58, 102.22 -51.07, -34.93 in-in in 8.4796 Saltbr-in 2.8987 HRD-in -72.18, -47.68 71.87, 13.91 in-in-in SNCiii in-in ActLoopNT-in 2.8463 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -94.59, 132.11 APE9-dihe-in -138.43, 150.74 APE8-dihe-in -80.34, 79.03 APE8-rot-na 34.01 APE67-dihe-in -74.66, -9.01 -47.69, -41.15 APE12-dist-na 12.5064 APE11-dist-na 11.236 APE10-dist-na 11.2771 APE9-dist-in 7.1391 T790M,L858R,V948R None None XRAY 2.17 0.196 0.285 A 348.0 309.0 0 30 30 0 [[712, 970]] 1.0 8d73 Homo sapiens TYR_EGFR_HUMAN TYR 7.7e-87 296.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8D73B P00533 704 1012 1210.0 QCR:1502 Type1.5_Back Active DFGin 5.3954 14.6503 BLAminus -137.92, -166.35 72.18, 68.71 -94.69, 12.26 295.76, 102.32 -51.71, -34.28 in-in in 8.4456 Saltbr-in 2.9106 HRD-in -71.23, -48.01 72.11, 12.51 in-in-in SNCiii in-in ActLoopNT-in 2.8549 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -97.18, 131.42 APE9-dihe-in -139.31, 151.96 APE8-dihe-in -80.51, 78.64 APE8-rot-na 33.78 APE67-dihe-in -74.28, -9.24 -48.16, -40.87 APE12-dist-na 12.7008 APE11-dist-na 11.3639 APE10-dist-na 11.4097 APE9-dist-in 7.2216 T790M,L858R,V948R None None XRAY 2.17 0.196 0.285 B 348.0 309.0 0 30 30 0 [[712, 970]] 1.0 8d73 Homo sapiens TYR_EGFR_HUMAN TYR 7.7e-87 296.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 8D73 — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name