PDB: 8BM2 — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8BM2A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 8BM2A O60674 840 1132 1132.0 QQC:61201 Type1 Active DFGin 6.4951 13.6679 BLAminus -136.57, -149.18 56.25, 58.85 -83.86, 18.34 294.62, 85.88 -65.29, -21.3 in-in in 8.604 Saltbr-in 2.7094 HRD-in -74.1, -44.85 72.69, -1.57 in-in-in SNCiii in-in ActLoopNT-in 2.8051 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -72.48, 126.84 APE9-dihe-in -115.75, 132.68 APE8-dihe-in -77.01, 74.29 APE8-rot-na 31.66 APE67-dihe-in -77.57, -2.52 -60.5, -31.86 APE12-dist-na 11.4299 APE11-dist-na 10.2534 APE10-dist-na 10.6517 APE9-dist-in 7.2899 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 1.5 0.178 0.202 A 317.0 293.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 8bm2 TYR_JAK2-2_HUMAN TYR 3.2e-87 298.1 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8BM2B O60674 840 1132 1132.0 QQC:61201 Type1 Active DFGin 6.4442 13.9864 BLAminus -119.78, -156.07 50.59, 71.59 -91.98, 24.86 295.0, 85.76 -67.95, -20.12 in-in in 8.6997 Saltbr-in 2.9003 HRD-in -70.73, -45.45 70.42, 4.42 in-in-in SNCiii in-in ActLoopNT-in 2.8213 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -69.07, 132.24 APE9-dihe-in -113.55, 136.93 APE8-dihe-in -79.1, 74.25 APE8-rot-na 36.64 APE67-dihe-in -79.53, -0.67 -57.94, -30.78 APE12-dist-na 10.8343 APE11-dist-na 9.5045 APE10-dist-na 11.0298 APE9-dist-in 7.2505 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 1.5 0.178 0.202 B 317.0 293.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 8bm2 TYR_JAK2-2_HUMAN TYR 3.2e-87 298.1 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 8BM2 — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8BM2A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 8BM2A O60674 840 1132 1132.0 QQC:61201 Type1 Active DFGin 6.4951 13.6679 BLAminus -136.57, -149.18 56.25, 58.85 -83.86, 18.34 294.62, 85.88 -65.29, -21.3 in-in in 8.604 Saltbr-in 2.7094 HRD-in -74.1, -44.85 72.69, -1.57 in-in-in SNCiii in-in ActLoopNT-in 2.8051 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -72.48, 126.84 APE9-dihe-in -115.75, 132.68 APE8-dihe-in -77.01, 74.29 APE8-rot-na 31.66 APE67-dihe-in -77.57, -2.52 -60.5, -31.86 APE12-dist-na 11.4299 APE11-dist-na 10.2534 APE10-dist-na 10.6517 APE9-dist-in 7.2899 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 1.5 0.178 0.202 A 317.0 293.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 8bm2 Homo sapiens TYR_JAK2-2_HUMAN TYR 3.2e-87 298.1 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8BM2B O60674 840 1132 1132.0 QQC:61201 Type1 Active DFGin 6.4442 13.9864 BLAminus -119.78, -156.07 50.59, 71.59 -91.98, 24.86 295.0, 85.76 -67.95, -20.12 in-in in 8.6997 Saltbr-in 2.9003 HRD-in -70.73, -45.45 70.42, 4.42 in-in-in SNCiii in-in ActLoopNT-in 2.8213 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -69.07, 132.24 APE9-dihe-in -113.55, 136.93 APE8-dihe-in -79.1, 74.25 APE8-rot-na 36.64 APE67-dihe-in -79.53, -0.67 -57.94, -30.78 APE12-dist-na 10.8343 APE11-dist-na 9.5045 APE10-dist-na 11.0298 APE9-dist-in 7.2505 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 1.5 0.178 0.202 B 317.0 293.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 8bm2 Homo sapiens TYR_JAK2-2_HUMAN TYR 3.2e-87 298.1 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 8BM2 — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name