PDB: 8B54 — CMGC CDK2_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8B54A
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 8B54A P24941 1 294 298.0 P2V:301 Type1 Inactive DFGin 6.514 15.247 BLAminus -128.12, 170.62 59.1, 85.13 -100.08, 22.73 286.24, 67.7 -63.02, -30.99 in-in in 8.487 Saltbr-in 2.815 HRD-in -82.86, -54.52 68.83, 22.28 in-in-out SNCiio in-out ActLoopNT-in 3.055 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -99.69, 158.44 APE9-dihe-na 80.04, 135.87 APE8-dihe-in -60.84, 136.8 APE8-rot-out 36.15 APE67-dihe-in -51.66, -27.71 -44.78, -57.24 APE12-dist-in 13.431 APE11-dist-in 12.01 APE10-dist-in 7.248 APE9-dist-in 3.365 None TPO160 TPO160 XRAY 2.6 0.234 0.287 A 299 292 2 0 0 0 [[4, 286]] 1.0 8b54 CMGC_CDK2_HUMAN CMGC 6.4e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 8B54C P24941 1 294 298.0 P2V:302 Type1 Active DFGin 6.514 15.099 BLAminus -122.54, 172.83 60.19, 84.09 -98.1, 19.4 281.6, 70.02 -54.41, -41.26 in-in in 8.374 Saltbr-in 2.81 HRD-in -75.35, -55.92 72.59, 17.93 in-in-in SNCiii in-in ActLoopNT-in 2.874 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -80.35, 158.96 APE9-dihe-na 82.94, 134.61 APE8-dihe-in -57.65, 133.89 APE8-rot-in 307.69 APE67-dihe-in -50.27, -27.61 -42.77, -59.14 APE12-dist-in 13.319 APE11-dist-in 12.023 APE10-dist-in 7.065 APE9-dist-in 3.348 None TPO160 TPO160 XRAY 2.6 0.234 0.287 C 299 292 2 0 0 0 [[4, 286]] 1.0 8b54 CMGC_CDK2_HUMAN CMGC 6.4e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

PDB: 8B54 — CMGC CDK2_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8B54A
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 8B54A P24941 1 294 298.0 P2V:301 Type1 Inactive DFGin 6.514 15.247 BLAminus -128.12, 170.62 59.1, 85.13 -100.08, 22.73 286.24, 67.7 -63.02, -30.99 in-in in 8.487 Saltbr-in 2.815 HRD-in -82.86, -54.52 68.83, 22.28 in-in-out SNCiio in-out ActLoopNT-in 3.055 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -99.69, 158.44 APE9-dihe-na 80.04, 135.87 APE8-dihe-in -60.84, 136.8 APE8-rot-out 36.15 APE67-dihe-in -51.66, -27.71 -44.78, -57.24 APE12-dist-in 13.431 APE11-dist-in 12.01 APE10-dist-in 7.248 APE9-dist-in 3.365 None TPO160 TPO160 XRAY 2.6 0.234 0.287 A 299 292 2 0 0 0 [[4, 286]] 1.0 8b54 Homo sapiens CMGC_CDK2_HUMAN CMGC 6.4e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 8B54C P24941 1 294 298.0 P2V:302 Type1 Active DFGin 6.514 15.099 BLAminus -122.54, 172.83 60.19, 84.09 -98.1, 19.4 281.6, 70.02 -54.41, -41.26 in-in in 8.374 Saltbr-in 2.81 HRD-in -75.35, -55.92 72.59, 17.93 in-in-in SNCiii in-in ActLoopNT-in 2.874 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -80.35, 158.96 APE9-dihe-na 82.94, 134.61 APE8-dihe-in -57.65, 133.89 APE8-rot-in 307.69 APE67-dihe-in -50.27, -27.61 -42.77, -59.14 APE12-dist-in 13.319 APE11-dist-in 12.023 APE10-dist-in 7.065 APE9-dist-in 3.348 None TPO160 TPO160 XRAY 2.6 0.234 0.287 C 299 292 2 0 0 0 [[4, 286]] 1.0 8b54 Homo sapiens CMGC_CDK2_HUMAN CMGC 6.4e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

PDB: 8B54 — CMGC CDK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name