PDB: 7XC1 — CMGC MK01_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7XC1B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK1 MK01_HUMAN 7XC1B P28482 12 357 360.0 5ID:402 Type1 Inactive DFGin 6.7495 15.8478 BLAminus -136.86, 178.87 56.25, 81.89 -92.76, 18.78 288.3, 68.54 -60.11, -21.88 in-in in 9.1742 Saltbr-in 3.022 HRD-in -76.63, -53.91 78.34, 9.0 in-in-out SNCiio in-out ActLoopNT-in 2.7077 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_ioii APE10-dihe-na -112.15, 106.32 APE9-dihe-na 73.8, 141.03 APE8-dihe-in -61.74, 138.85 APE8-rot-in 297.46 APE67-dihe-in -56.69, -24.12 -44.69, -58.48 APE12-dist-in 8.3558 APE11-dist-out 7.5573 APE10-dist-in 7.8496 APE9-dist-in 3.0354 None None NEP125 XRAY 2.09 0.232 0.271 B 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 7xc1 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 7XC1A P28482 10 360 360.0 5ID:401,B8Z:405 Type1,Allosteric Inactive DFGin 6.7078 15.976 BLAminus -137.71, -179.56 58.01, 78.42 -93.4, 30.18 285.99, 69.28 -65.81, -34.24 in-in in 9.5275 Saltbr-in 2.9997 HRD-in -74.95, -51.9 73.0, -2.02 in-in-out SNCiio in-out ActLoopNT-in 2.7443 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_ioii APE10-dihe-na -122.62, 101.42 APE9-dihe-na 74.74, 135.42 APE8-dihe-in -55.35, 136.96 APE8-rot-in 306.98 APE67-dihe-in -57.04, -22.83 -48.83, -53.13 APE12-dist-in 8.7119 APE11-dist-out 7.512 APE10-dist-in 7.787 APE9-dist-in 3.0162 None None NEP125 XRAY 2.09 0.232 0.271 A 368.0 351.0 0 31 31 0 [[25, 313]] 1.0 7xc1 CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1

PDB: 7XC1 — CMGC MK01_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7XC1B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK1 MK01_HUMAN 7XC1B P28482 12 357 360.0 5ID:402 Type1 Inactive DFGin 6.7495 15.8478 BLAminus -136.86, 178.87 56.25, 81.89 -92.76, 18.78 288.3, 68.54 -60.11, -21.88 in-in in 9.1742 Saltbr-in 3.022 HRD-in -76.63, -53.91 78.34, 9.0 in-in-out SNCiio in-out ActLoopNT-in 2.7077 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_ioii APE10-dihe-na -112.15, 106.32 APE9-dihe-na 73.8, 141.03 APE8-dihe-in -61.74, 138.85 APE8-rot-in 297.46 APE67-dihe-in -56.69, -24.12 -44.69, -58.48 APE12-dist-in 8.3558 APE11-dist-out 7.5573 APE10-dist-in 7.8496 APE9-dist-in 3.0354 None None NEP125 XRAY 2.09 0.232 0.271 B 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 7xc1 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 7XC1A P28482 10 360 360.0 5ID:401,B8Z:405 Type1,Allosteric Inactive DFGin 6.7078 15.976 BLAminus -137.71, -179.56 58.01, 78.42 -93.4, 30.18 285.99, 69.28 -65.81, -34.24 in-in in 9.5275 Saltbr-in 2.9997 HRD-in -74.95, -51.9 73.0, -2.02 in-in-out SNCiio in-out ActLoopNT-in 2.7443 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_ioii APE10-dihe-na -122.62, 101.42 APE9-dihe-na 74.74, 135.42 APE8-dihe-in -55.35, 136.96 APE8-rot-in 306.98 APE67-dihe-in -57.04, -22.83 -48.83, -53.13 APE12-dist-in 8.7119 APE11-dist-out 7.512 APE10-dist-in 7.787 APE9-dist-in 3.0162 None None NEP125 XRAY 2.09 0.232 0.271 A 368.0 351.0 0 31 31 0 [[25, 313]] 1.0 7xc1 Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1

PDB: 7XC1 — CMGC MK01_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name