PDB: 7W5O — CMGC MK01_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7W5OB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK1 MK01_HUMAN 7W5OB P28482 12 357 360.0 6GI:606 Allosteric Inactive DFGin 6.7291 15.966 BLAminus -130.99, -179.63 60.79, 79.04 -97.44, 21.46 284.57, 69.25 -51.76, -37.4 in-in in 9.205 Saltbr-in 2.9255 HRD-in -89.57, -49.89 81.11, -2.76 in-in-out SNCiio in-out ActLoopNT-in 2.6945 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_ioii APE10-dihe-na -127.79, 113.11 APE9-dihe-na 67.74, 140.06 APE8-dihe-in -61.14, 150.09 APE8-rot-in 295.42 APE67-dihe-in -62.08, -24.55 -59.37, -51.13 APE12-dist-in 8.0847 APE11-dist-out 7.278 APE10-dist-in 7.6425 APE9-dist-in 2.9693 None None NEP125 XRAY 2.35 0.228 0.279 B 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 7w5o CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 7W5OA P28482 11 360 360.0 5ID:401 Type1 Inactive DFGin 6.7259 16.0736 BLAminus -134.06, -178.68 57.89, 83.45 -97.58, 26.47 285.78, 74.05 -62.2, -23.74 in-out in 9.5977 Saltbr-out 3.6644 HRD-in -64.25, -57.62 81.95, -6.27 out-in-out SNCoio in-out ActLoopNT-in 2.8418 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_ioii APE10-dihe-na -125.26, 105.21 APE9-dihe-na 77.53, 139.94 APE8-dihe-in -62.13, 139.76 APE8-rot-in 304.97 APE67-dihe-in -67.0, -21.21 -48.23, -45.39 APE12-dist-in 8.898 APE11-dist-out 7.5203 APE10-dist-in 7.6672 APE9-dist-in 3.0549 None None NEP125 XRAY 2.35 0.228 0.279 A 368.0 350.0 0 31 31 0 [[25, 313]] 1.0 7w5o CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1

PDB: 7W5O — CMGC MK01_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7W5OB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK1 MK01_HUMAN 7W5OB P28482 12 357 360.0 6GI:606 Allosteric Inactive DFGin 6.7291 15.966 BLAminus -130.99, -179.63 60.79, 79.04 -97.44, 21.46 284.57, 69.25 -51.76, -37.4 in-in in 9.205 Saltbr-in 2.9255 HRD-in -89.57, -49.89 81.11, -2.76 in-in-out SNCiio in-out ActLoopNT-in 2.6945 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_ioii APE10-dihe-na -127.79, 113.11 APE9-dihe-na 67.74, 140.06 APE8-dihe-in -61.14, 150.09 APE8-rot-in 295.42 APE67-dihe-in -62.08, -24.55 -59.37, -51.13 APE12-dist-in 8.0847 APE11-dist-out 7.278 APE10-dist-in 7.6425 APE9-dist-in 2.9693 None None NEP125 XRAY 2.35 0.228 0.279 B 368.0 346.0 0 31 31 0 [[25, 313]] 1.0 7w5o Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 7W5OA P28482 11 360 360.0 5ID:401 Type1 Inactive DFGin 6.7259 16.0736 BLAminus -134.06, -178.68 57.89, 83.45 -97.58, 26.47 285.78, 74.05 -62.2, -23.74 in-out in 9.5977 Saltbr-out 3.6644 HRD-in -64.25, -57.62 81.95, -6.27 out-in-out SNCoio in-out ActLoopNT-in 2.8418 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_ioii APE10-dihe-na -125.26, 105.21 APE9-dihe-na 77.53, 139.94 APE8-dihe-in -62.13, 139.76 APE8-rot-in 304.97 APE67-dihe-in -67.0, -21.21 -48.23, -45.39 APE12-dist-in 8.898 APE11-dist-out 7.5203 APE10-dist-in 7.6672 APE9-dist-in 3.0549 None None NEP125 XRAY 2.35 0.228 0.279 A 368.0 350.0 0 31 31 0 [[25, 313]] 1.0 7w5o Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.9e-86 293.6 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1

PDB: 7W5O — CMGC MK01_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name