PDB: 7T4J — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7T4JA
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7T4JA P00533 701 984 1210.0 R28:61101 Type1 Inactive DFGin 6.008 14.415 BLAminus -144.5, 169.5 68.77, 85.47 -96.42, 20.57 291.54, 77.61 -59.75, -25.89 in-in in 8.017 Saltbr-in 2.568 HRD-in -76.71, -52.5 81.16, 2.81 in-in-out SNCiio in-out ActLoopNT-in 2.877 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out 45.96, 61.38 APE9-dihe-in -145.01, 131.44 APE8-dihe-in -84.06, 121.96 APE8-rot-na 31.03 APE67-dihe-in -61.46, 1.98 -82.97, -44.13 APE12-dist-na 11.773 APE11-dist-na 11.055 APE10-dist-na 8.533 APE9-dist-in 6.334 V948R None None XRAY 2.2 0.227 0.278 A 331 276 8 0 0 0 [[712, 970]] 1.0 7t4j TYR_EGFR_HUMAN TYR 1.2e-85 293.0 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7T4JB P00533 701 984 1210.0 R28:61101 Type1 Active DFGin 6.154 14.095 BLAminus -144.13, 179.52 58.61, 83.85 -92.13, 21.8 294.24, 75.73 -54.65, -26.76 in-in in 7.881 Saltbr-in 2.775 HRD-in -69.57, -54.49 84.7, -3.58 in-in-in SNCiii in-in ActLoopNT-in 2.806 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -117.5, 142.26 APE9-dihe-in -155.99, 150.11 APE8-dihe-in -82.77, 101.36 APE8-rot-na 36.83 APE67-dihe-in -75.7, -4.6 -67.21, -37.02 APE12-dist-na 11.913 APE11-dist-na 10.71 APE10-dist-na 10.255 APE9-dist-in 6.477 V948R None None XRAY 2.2 0.227 0.278 B 331 275 9 0 0 0 [[712, 970]] 1.0 7t4j TYR_EGFR_HUMAN TYR 1.2e-85 293.0 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 7T4J — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7T4JA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7T4JA P00533 701 984 1210.0 R28:61101 Type1 Inactive DFGin 6.008 14.415 BLAminus -144.5, 169.5 68.77, 85.47 -96.42, 20.57 291.54, 77.61 -59.75, -25.89 in-in in 8.017 Saltbr-in 2.568 HRD-in -76.71, -52.5 81.16, 2.81 in-in-out SNCiio in-out ActLoopNT-in 2.877 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out 45.96, 61.38 APE9-dihe-in -145.01, 131.44 APE8-dihe-in -84.06, 121.96 APE8-rot-na 31.03 APE67-dihe-in -61.46, 1.98 -82.97, -44.13 APE12-dist-na 11.773 APE11-dist-na 11.055 APE10-dist-na 8.533 APE9-dist-in 6.334 V948R None None XRAY 2.2 0.227 0.278 A 331 276 8 0 0 0 [[712, 970]] 1.0 7t4j Homo sapiens TYR_EGFR_HUMAN TYR 1.2e-85 293.0 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7T4JB P00533 701 984 1210.0 R28:61101 Type1 Active DFGin 6.154 14.095 BLAminus -144.13, 179.52 58.61, 83.85 -92.13, 21.8 294.24, 75.73 -54.65, -26.76 in-in in 7.881 Saltbr-in 2.775 HRD-in -69.57, -54.49 84.7, -3.58 in-in-in SNCiii in-in ActLoopNT-in 2.806 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -117.5, 142.26 APE9-dihe-in -155.99, 150.11 APE8-dihe-in -82.77, 101.36 APE8-rot-na 36.83 APE67-dihe-in -75.7, -4.6 -67.21, -37.02 APE12-dist-na 11.913 APE11-dist-na 10.71 APE10-dist-na 10.255 APE9-dist-in 6.477 V948R None None XRAY 2.2 0.227 0.278 B 331 275 9 0 0 0 [[712, 970]] 1.0 7t4j Homo sapiens TYR_EGFR_HUMAN TYR 1.2e-85 293.0 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 7T4J — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name