PDB: 7T4J — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7T4JA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7T4JA P00533 701 984 1210.0 R28:61101 Type1 Inactive DFGin 6.0084 14.4151 BLAminus -144.5, 169.5 68.77, 85.47 -96.42, 20.57 291.54, 77.61 -59.75, -25.89 in-in in 8.0165 Saltbr-in 2.5684 HRD-in -76.71, -52.5 81.16, 2.81 in-in-out SNCiio in-out ActLoopNT-in 2.8772 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out 45.96, 61.38 APE9-dihe-in -145.01, 131.44 APE8-dihe-in -84.06, 121.96 APE8-rot-na 31.03 APE67-dihe-in -61.46, 1.98 -82.97, -44.13 APE12-dist-na 11.7729 APE11-dist-na 11.0549 APE10-dist-na 8.5325 APE9-dist-in 6.3336 V948R None None XRAY 2.2 0.227 0.278 A 331.0 276.0 8 30 30 0 [[712, 970]] 1.0 7t4j TYR_EGFR_HUMAN TYR 1.2e-85 293.0 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7T4JB P00533 701 984 1210.0 R28:61101 Type1 Active DFGin 6.1541 14.0955 BLAminus -144.13, 179.52 58.61, 83.85 -92.13, 21.8 294.24, 75.73 -54.65, -26.76 in-in in 7.8808 Saltbr-in 2.7747 HRD-in -69.57, -54.49 84.7, -3.58 in-in-in SNCiii in-in ActLoopNT-in 2.8058 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -117.5, 142.26 APE9-dihe-in -155.99, 150.11 APE8-dihe-in -82.77, 101.36 APE8-rot-na 36.83 APE67-dihe-in -75.7, -4.6 -67.21, -37.02 APE12-dist-na 11.9131 APE11-dist-na 10.7098 APE10-dist-na 10.2555 APE9-dist-in 6.4774 V948R None None XRAY 2.2 0.227 0.278 B 331.0 275.0 9 30 30 0 [[712, 970]] 1.0 7t4j TYR_EGFR_HUMAN TYR 1.2e-85 293.0 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 7T4J — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7T4JA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7T4JA P00533 701 984 1210.0 R28:61101 Type1 Inactive DFGin 6.0084 14.4151 BLAminus -144.5, 169.5 68.77, 85.47 -96.42, 20.57 291.54, 77.61 -59.75, -25.89 in-in in 8.0165 Saltbr-in 2.5684 HRD-in -76.71, -52.5 81.16, 2.81 in-in-out SNCiio in-out ActLoopNT-in 2.8772 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out 45.96, 61.38 APE9-dihe-in -145.01, 131.44 APE8-dihe-in -84.06, 121.96 APE8-rot-na 31.03 APE67-dihe-in -61.46, 1.98 -82.97, -44.13 APE12-dist-na 11.7729 APE11-dist-na 11.0549 APE10-dist-na 8.5325 APE9-dist-in 6.3336 V948R None None XRAY 2.2 0.227 0.278 A 331.0 276.0 8 30 30 0 [[712, 970]] 1.0 7t4j Homo sapiens TYR_EGFR_HUMAN TYR 1.2e-85 293.0 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7T4JB P00533 701 984 1210.0 R28:61101 Type1 Active DFGin 6.1541 14.0955 BLAminus -144.13, 179.52 58.61, 83.85 -92.13, 21.8 294.24, 75.73 -54.65, -26.76 in-in in 7.8808 Saltbr-in 2.7747 HRD-in -69.57, -54.49 84.7, -3.58 in-in-in SNCiii in-in ActLoopNT-in 2.8058 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -117.5, 142.26 APE9-dihe-in -155.99, 150.11 APE8-dihe-in -82.77, 101.36 APE8-rot-na 36.83 APE67-dihe-in -75.7, -4.6 -67.21, -37.02 APE12-dist-na 11.9131 APE11-dist-na 10.7098 APE10-dist-na 10.2555 APE9-dist-in 6.4774 V948R None None XRAY 2.2 0.227 0.278 B 331.0 275.0 9 30 30 0 [[712, 970]] 1.0 7t4j Homo sapiens TYR_EGFR_HUMAN TYR 1.2e-85 293.0 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 7T4J — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name