PDB: 7O7K — CMGC DYR1A_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7O7KA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 7O7KA Q13627 134 480 763.0 6ZV:803,LI:813 Type1,Allosteric Inactive DFGin 7.479 14.978 BLAminus -123.84, 172.32 71.95, 80.41 -97.61, 20.16 282.45, 81.55 -75.41, -18.82 in-in in 8.732 Saltbr-in 2.569 HRD-in -66.95, -44.76 74.49, -2.2 in-in-out SNCiio in-out ActLoopNT-in 2.763 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -120.45, 171.41 APE9-dihe-na 76.66, 152.25 APE8-dihe-in -71.23, 142.04 APE8-rot-out 204.57 APE67-dihe-in -61.2, -25.53 -57.62, -46.09 APE12-dist-in 13.826 APE11-dist-in 12.396 APE10-dist-in 7.934 APE9-dist-in 3.209 None PTR321 PTR321 XRAY 1.82 0.179 0.205 A 361 345 2 0 0 0 [[159, 479]] 1.0 7o7k CMGC_DYRK1A_HUMAN CMGC 8.4e-91 310.2 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 7O7KB Q13627 133 480 763.0 6ZV:504,LI:516 Type1,Allosteric Inactive DFGin 7.549 15.002 BLAminus -123.44, 173.38 69.65, 80.66 -97.78, 19.84 280.19, 88.12 -76.56, -16.84 in-in in 8.721 Saltbr-in 2.45 HRD-in -66.14, -44.61 73.06, -2.94 in-in-out SNCiio in-out ActLoopNT-in 2.793 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioi APE10-dihe-na -122.41, 168.28 APE9-dihe-na 77.46, 151.66 APE8-dihe-in -70.04, 138.71 APE8-rot-out 178.34 APE67-dihe-in -60.28, -25.12 -56.13, -47.11 APE12-dist-in 13.885 APE11-dist-in 12.364 APE10-dist-out 8.042 APE9-dist-in 3.108 None PTR321 PTR321 XRAY 1.82 0.179 0.205 B 361 345 3 0 0 0 [[159, 479]] 1.0 7o7k CMGC_DYRK1A_HUMAN CMGC 8.4e-91 310.2 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

PDB: 7O7K — CMGC DYR1A_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7O7KA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 7O7KA Q13627 134 480 763.0 6ZV:803,LI:813 Type1,Allosteric Inactive DFGin 7.479 14.978 BLAminus -123.84, 172.32 71.95, 80.41 -97.61, 20.16 282.45, 81.55 -75.41, -18.82 in-in in 8.732 Saltbr-in 2.569 HRD-in -66.95, -44.76 74.49, -2.2 in-in-out SNCiio in-out ActLoopNT-in 2.763 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -120.45, 171.41 APE9-dihe-na 76.66, 152.25 APE8-dihe-in -71.23, 142.04 APE8-rot-out 204.57 APE67-dihe-in -61.2, -25.53 -57.62, -46.09 APE12-dist-in 13.826 APE11-dist-in 12.396 APE10-dist-in 7.934 APE9-dist-in 3.209 None PTR321 PTR321 XRAY 1.82 0.179 0.205 A 361 345 2 0 0 0 [[159, 479]] 1.0 7o7k Homo sapiens CMGC_DYRK1A_HUMAN CMGC 8.4e-91 310.2 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 7O7KB Q13627 133 480 763.0 6ZV:504,LI:516 Type1,Allosteric Inactive DFGin 7.549 15.002 BLAminus -123.44, 173.38 69.65, 80.66 -97.78, 19.84 280.19, 88.12 -76.56, -16.84 in-in in 8.721 Saltbr-in 2.45 HRD-in -66.14, -44.61 73.06, -2.94 in-in-out SNCiio in-out ActLoopNT-in 2.793 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioi APE10-dihe-na -122.41, 168.28 APE9-dihe-na 77.46, 151.66 APE8-dihe-in -70.04, 138.71 APE8-rot-out 178.34 APE67-dihe-in -60.28, -25.12 -56.13, -47.11 APE12-dist-in 13.885 APE11-dist-in 12.364 APE10-dist-out 8.042 APE9-dist-in 3.108 None PTR321 PTR321 XRAY 1.82 0.179 0.205 B 361 345 3 0 0 0 [[159, 479]] 1.0 7o7k Homo sapiens CMGC_DYRK1A_HUMAN CMGC 8.4e-91 310.2 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

PDB: 7O7K — CMGC DYR1A_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name