PDB: 7LGS — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 4
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 7LGSB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7LGSA P00533 702 984 1210.0 Q6K:61101 Type1 Active DFGin 5.7981 13.8478 BLAminus -148.14, -179.86 66.83, 93.39 -109.24, 25.55 296.83, 82.02 -45.71, -51.38 in-in in 8.2543 Saltbr-in 2.9139 HRD-in -61.85, -36.93 72.75, -6.16 in-in-in SNCiii in-in ActLoopNT-in 2.819 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -110.14, 118.29 APE9-dihe-in -124.18, 152.07 APE8-dihe-in -87.87, 98.71 APE8-rot-na 33.29 APE67-dihe-in -76.07, 20.02 -59.01, -47.71 APE12-dist-na 10.7345 APE11-dist-na 9.7169 APE10-dist-na 10.4408 APE9-dist-in 6.7352 V948R None None XRAY 3.1 0.241 0.305 A 331.0 280.0 3 30 30 0 [[712, 970]] 1.0 7lgs TYR_EGFR_HUMAN TYR 1.2e-85 293.0 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LGSB P00533 702 984 1210.0 Q6K:62703 Type1 Active DFGin 6.0647 14.1319 BLAminus -143.64, 174.55 75.07, 86.01 -103.95, 23.76 297.26, 76.2 -47.19, -46.41 in-in in 8.4887 Saltbr-in 2.9246 HRD-in -70.84, -32.42 56.54, 26.28 in-in-in SNCiii in-in ActLoopNT-in 2.8034 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -77.24, 133.4 APE9-dihe-in -137.17, 157.48 APE8-dihe-in -85.36, 106.29 APE8-rot-na 33.1 APE67-dihe-in -76.15, 7.94 -70.75, -39.01 APE12-dist-na 11.9069 APE11-dist-na 9.4262 APE10-dist-na 10.2754 APE9-dist-in 6.571 V948R None None XRAY 3.1 0.241 0.305 B 331.0 283.0 0 30 30 0 [[712, 970]] 1.0 7lgs TYR_EGFR_HUMAN TYR 1.2e-85 293.0 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LGSC P00533 701 984 1210.0 Q6K:61101 Type1 Active DFGin 5.7878 13.8359 BLAminus -144.73, 172.67 64.73, 92.38 -102.97, 22.8 303.24, 82.51 -50.29, -34.49 in-in in 8.064 Saltbr-in 3.457 HRD-in -60.12, -39.38 78.78, -23.89 in-in-in SNCiii in-in ActLoopNT-in 3.2017 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -145.58, 117.71 APE9-dihe-in -124.38, 146.08 APE8-dihe-in -62.99, 124.66 APE8-rot-na 21.56 APE67-dihe-in -104.68, 1.44 -87.08, -8.44 APE12-dist-na 11.5824 APE11-dist-na 9.2892 APE10-dist-na 9.9205 APE9-dist-in 6.4585 V948R None None XRAY 3.1 0.241 0.305 C 331.0 280.0 4 30 30 0 [[712, 970]] 1.0 7lgs TYR_EGFR_HUMAN TYR 1.2e-85 293.0 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LGSD P00533 701 984 1210.0 Q6K:62500 Type1 Active DFGin 5.7168 14.0238 BLAminus -133.47, 170.68 74.78, 90.52 -109.47, 24.05 298.1, 77.01 -64.19, -15.34 in-in in 8.2009 Saltbr-in 2.7856 HRD-in -55.31, -49.72 74.8, 6.32 in-in-in SNCiii in-in ActLoopNT-in 2.8367 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -72.9, 130.33 APE9-dihe-in -138.85, 149.74 APE8-dihe-in -80.14, 110.14 APE8-rot-na 30.64 APE67-dihe-in -83.2, -1.33 -71.86, -29.25 APE12-dist-na 11.726 APE11-dist-na 9.5426 APE10-dist-na 10.2785 APE9-dist-in 6.3531 V948R None None XRAY 3.1 0.241 0.305 D 331.0 276.0 8 30 30 0 [[712, 970]] 1.0 7lgs TYR_EGFR_HUMAN TYR 1.2e-85 293.0 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 7LGS — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 4
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 7LGSB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7LGSA P00533 702 984 1210.0 Q6K:61101 Type1 Active DFGin 5.7981 13.8478 BLAminus -148.14, -179.86 66.83, 93.39 -109.24, 25.55 296.83, 82.02 -45.71, -51.38 in-in in 8.2543 Saltbr-in 2.9139 HRD-in -61.85, -36.93 72.75, -6.16 in-in-in SNCiii in-in ActLoopNT-in 2.819 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -110.14, 118.29 APE9-dihe-in -124.18, 152.07 APE8-dihe-in -87.87, 98.71 APE8-rot-na 33.29 APE67-dihe-in -76.07, 20.02 -59.01, -47.71 APE12-dist-na 10.7345 APE11-dist-na 9.7169 APE10-dist-na 10.4408 APE9-dist-in 6.7352 V948R None None XRAY 3.1 0.241 0.305 A 331.0 280.0 3 30 30 0 [[712, 970]] 1.0 7lgs Homo sapiens TYR_EGFR_HUMAN TYR 1.2e-85 293.0 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LGSB P00533 702 984 1210.0 Q6K:62703 Type1 Active DFGin 6.0647 14.1319 BLAminus -143.64, 174.55 75.07, 86.01 -103.95, 23.76 297.26, 76.2 -47.19, -46.41 in-in in 8.4887 Saltbr-in 2.9246 HRD-in -70.84, -32.42 56.54, 26.28 in-in-in SNCiii in-in ActLoopNT-in 2.8034 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -77.24, 133.4 APE9-dihe-in -137.17, 157.48 APE8-dihe-in -85.36, 106.29 APE8-rot-na 33.1 APE67-dihe-in -76.15, 7.94 -70.75, -39.01 APE12-dist-na 11.9069 APE11-dist-na 9.4262 APE10-dist-na 10.2754 APE9-dist-in 6.571 V948R None None XRAY 3.1 0.241 0.305 B 331.0 283.0 0 30 30 0 [[712, 970]] 1.0 7lgs Homo sapiens TYR_EGFR_HUMAN TYR 1.2e-85 293.0 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LGSC P00533 701 984 1210.0 Q6K:61101 Type1 Active DFGin 5.7878 13.8359 BLAminus -144.73, 172.67 64.73, 92.38 -102.97, 22.8 303.24, 82.51 -50.29, -34.49 in-in in 8.064 Saltbr-in 3.457 HRD-in -60.12, -39.38 78.78, -23.89 in-in-in SNCiii in-in ActLoopNT-in 3.2017 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -145.58, 117.71 APE9-dihe-in -124.38, 146.08 APE8-dihe-in -62.99, 124.66 APE8-rot-na 21.56 APE67-dihe-in -104.68, 1.44 -87.08, -8.44 APE12-dist-na 11.5824 APE11-dist-na 9.2892 APE10-dist-na 9.9205 APE9-dist-in 6.4585 V948R None None XRAY 3.1 0.241 0.305 C 331.0 280.0 4 30 30 0 [[712, 970]] 1.0 7lgs Homo sapiens TYR_EGFR_HUMAN TYR 1.2e-85 293.0 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LGSD P00533 701 984 1210.0 Q6K:62500 Type1 Active DFGin 5.7168 14.0238 BLAminus -133.47, 170.68 74.78, 90.52 -109.47, 24.05 298.1, 77.01 -64.19, -15.34 in-in in 8.2009 Saltbr-in 2.7856 HRD-in -55.31, -49.72 74.8, 6.32 in-in-in SNCiii in-in ActLoopNT-in 2.8367 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -72.9, 130.33 APE9-dihe-in -138.85, 149.74 APE8-dihe-in -80.14, 110.14 APE8-rot-na 30.64 APE67-dihe-in -83.2, -1.33 -71.86, -29.25 APE12-dist-na 11.726 APE11-dist-na 9.5426 APE10-dist-na 10.2785 APE9-dist-in 6.3531 V948R None None XRAY 3.1 0.241 0.305 D 331.0 276.0 8 30 30 0 [[712, 970]] 1.0 7lgs Homo sapiens TYR_EGFR_HUMAN TYR 1.2e-85 293.0 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 7LGS — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name