PDB: 7LGS — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 4
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 7LGSB
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7LGSA P00533 702 984 1210.0 Q6K:61101 Type1 Active DFGin 5.798 13.848 BLAminus -148.14, -179.86 66.83, 93.39 -109.24, 25.55 296.83, 82.02 -45.71, -51.38 in-in in 8.254 Saltbr-in 2.914 HRD-in -61.85, -36.93 72.75, -6.16 in-in-in SNCiii in-in ActLoopNT-in 2.819 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -110.14, 118.29 APE9-dihe-in -124.18, 152.07 APE8-dihe-in -87.87, 98.71 APE8-rot-na 33.29 APE67-dihe-in -76.07, 20.02 -59.01, -47.71 APE12-dist-na 10.735 APE11-dist-na 9.717 APE10-dist-na 10.441 APE9-dist-in 6.735 V948R None None XRAY 3.1 0.241 0.305 A 331 280 3 0 0 0 [[712, 970]] 1.0 7lgs TYR_EGFR_HUMAN TYR 1.2e-85 293.0 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LGSB P00533 702 984 1210.0 Q6K:62703 Type1 Active DFGin 6.065 14.132 BLAminus -143.64, 174.55 75.07, 86.01 -103.95, 23.76 297.26, 76.2 -47.19, -46.41 in-in in 8.489 Saltbr-in 2.925 HRD-in -70.84, -32.42 56.54, 26.28 in-in-in SNCiii in-in ActLoopNT-in 2.803 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -77.24, 133.4 APE9-dihe-in -137.17, 157.48 APE8-dihe-in -85.36, 106.29 APE8-rot-na 33.1 APE67-dihe-in -76.15, 7.94 -70.75, -39.01 APE12-dist-na 11.907 APE11-dist-na 9.426 APE10-dist-na 10.275 APE9-dist-in 6.571 V948R None None XRAY 3.1 0.241 0.305 B 331 283 0 0 0 0 [[712, 970]] 1.0 7lgs TYR_EGFR_HUMAN TYR 1.2e-85 293.0 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LGSC P00533 701 984 1210.0 Q6K:61101 Type1 Active DFGin 5.788 13.836 BLAminus -144.73, 172.67 64.73, 92.38 -102.97, 22.8 303.24, 82.51 -50.29, -34.49 in-in in 8.064 Saltbr-in 3.457 HRD-in -60.12, -39.38 78.78, -23.89 in-in-in SNCiii in-in ActLoopNT-in 3.202 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -145.58, 117.71 APE9-dihe-in -124.38, 146.08 APE8-dihe-in -62.99, 124.66 APE8-rot-na 21.56 APE67-dihe-in -104.68, 1.44 -87.08, -8.44 APE12-dist-na 11.582 APE11-dist-na 9.289 APE10-dist-na 9.921 APE9-dist-in 6.458 V948R None None XRAY 3.1 0.241 0.305 C 331 280 4 0 0 0 [[712, 970]] 1.0 7lgs TYR_EGFR_HUMAN TYR 1.2e-85 293.0 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LGSD P00533 701 984 1210.0 Q6K:62500 Type1 Active DFGin 5.717 14.024 BLAminus -133.47, 170.68 74.78, 90.52 -109.47, 24.05 298.1, 77.01 -64.19, -15.34 in-in in 8.201 Saltbr-in 2.786 HRD-in -55.31, -49.72 74.8, 6.32 in-in-in SNCiii in-in ActLoopNT-in 2.837 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -72.9, 130.33 APE9-dihe-in -138.85, 149.74 APE8-dihe-in -80.14, 110.14 APE8-rot-na 30.64 APE67-dihe-in -83.2, -1.33 -71.86, -29.25 APE12-dist-na 11.726 APE11-dist-na 9.543 APE10-dist-na 10.278 APE9-dist-in 6.353 V948R None None XRAY 3.1 0.241 0.305 D 331 276 8 0 0 0 [[712, 970]] 1.0 7lgs TYR_EGFR_HUMAN TYR 1.2e-85 293.0 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 7LGS — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 4
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 7LGSB
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7LGSA P00533 702 984 1210.0 Q6K:61101 Type1 Active DFGin 5.798 13.848 BLAminus -148.14, -179.86 66.83, 93.39 -109.24, 25.55 296.83, 82.02 -45.71, -51.38 in-in in 8.254 Saltbr-in 2.914 HRD-in -61.85, -36.93 72.75, -6.16 in-in-in SNCiii in-in ActLoopNT-in 2.819 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -110.14, 118.29 APE9-dihe-in -124.18, 152.07 APE8-dihe-in -87.87, 98.71 APE8-rot-na 33.29 APE67-dihe-in -76.07, 20.02 -59.01, -47.71 APE12-dist-na 10.735 APE11-dist-na 9.717 APE10-dist-na 10.441 APE9-dist-in 6.735 V948R None None XRAY 3.1 0.241 0.305 A 331 280 3 0 0 0 [[712, 970]] 1.0 7lgs Homo sapiens TYR_EGFR_HUMAN TYR 1.2e-85 293.0 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LGSB P00533 702 984 1210.0 Q6K:62703 Type1 Active DFGin 6.065 14.132 BLAminus -143.64, 174.55 75.07, 86.01 -103.95, 23.76 297.26, 76.2 -47.19, -46.41 in-in in 8.489 Saltbr-in 2.925 HRD-in -70.84, -32.42 56.54, 26.28 in-in-in SNCiii in-in ActLoopNT-in 2.803 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -77.24, 133.4 APE9-dihe-in -137.17, 157.48 APE8-dihe-in -85.36, 106.29 APE8-rot-na 33.1 APE67-dihe-in -76.15, 7.94 -70.75, -39.01 APE12-dist-na 11.907 APE11-dist-na 9.426 APE10-dist-na 10.275 APE9-dist-in 6.571 V948R None None XRAY 3.1 0.241 0.305 B 331 283 0 0 0 0 [[712, 970]] 1.0 7lgs Homo sapiens TYR_EGFR_HUMAN TYR 1.2e-85 293.0 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LGSC P00533 701 984 1210.0 Q6K:61101 Type1 Active DFGin 5.788 13.836 BLAminus -144.73, 172.67 64.73, 92.38 -102.97, 22.8 303.24, 82.51 -50.29, -34.49 in-in in 8.064 Saltbr-in 3.457 HRD-in -60.12, -39.38 78.78, -23.89 in-in-in SNCiii in-in ActLoopNT-in 3.202 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -145.58, 117.71 APE9-dihe-in -124.38, 146.08 APE8-dihe-in -62.99, 124.66 APE8-rot-na 21.56 APE67-dihe-in -104.68, 1.44 -87.08, -8.44 APE12-dist-na 11.582 APE11-dist-na 9.289 APE10-dist-na 9.921 APE9-dist-in 6.458 V948R None None XRAY 3.1 0.241 0.305 C 331 280 4 0 0 0 [[712, 970]] 1.0 7lgs Homo sapiens TYR_EGFR_HUMAN TYR 1.2e-85 293.0 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LGSD P00533 701 984 1210.0 Q6K:62500 Type1 Active DFGin 5.717 14.024 BLAminus -133.47, 170.68 74.78, 90.52 -109.47, 24.05 298.1, 77.01 -64.19, -15.34 in-in in 8.201 Saltbr-in 2.786 HRD-in -55.31, -49.72 74.8, 6.32 in-in-in SNCiii in-in ActLoopNT-in 2.837 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -72.9, 130.33 APE9-dihe-in -138.85, 149.74 APE8-dihe-in -80.14, 110.14 APE8-rot-na 30.64 APE67-dihe-in -83.2, -1.33 -71.86, -29.25 APE12-dist-na 11.726 APE11-dist-na 9.543 APE10-dist-na 10.278 APE9-dist-in 6.353 V948R None None XRAY 3.1 0.241 0.305 D 331 276 8 0 0 0 [[712, 970]] 1.0 7lgs Homo sapiens TYR_EGFR_HUMAN TYR 1.2e-85 293.0 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 7LGS — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name