PDB: 7APG — TYR JAK3_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 7APGC
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK3-2 JAK3_HUMAN 7APGA P52333 813 1103 1124.0 RQT:61201 Type1 Inactive DFGin 6.031 13.952 BLAminus -145.19, -172.66 53.39, 85.17 -97.7, 25.99 284.4, 73.93 -62.87, -25.47 in-in in 8.492 Saltbr-in 3.089 HRD-in -83.97, -50.23 79.99, -46.84 in-in-out SNCiio in-out ActLoopNT-in 2.913 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -120.14, 50.45 APE9-dihe-in -76.86, 156.83 APE8-dihe-in -73.67, 136.77 APE8-rot-na 351.29 APE67-dihe-in -81.27, -2.59 -94.73, -13.37 APE12-dist-na 10.678 APE11-dist-na 10.899 APE10-dist-na 13.601 APE9-dist-out 8.985 None None None XRAY 2.4 0.214 0.256 A 294 279 12 0 0 0 [[521, 779], [822, 1097]] 2.0 7apg TYR_JAK3-2_HUMAN TYR 4e-80 274.8 1 260 260 966 967 968 970 972 855 871 875 946 948 947 949 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 7APGB P52333 814 1103 1124.0 RQT:61201 Type1 Inactive DFGin 6.039 14.069 BLAminus -144.05, -171.58 55.33, 84.79 -97.11, 25.47 284.03, 75.74 -64.12, -25.92 in-in in 8.44 Saltbr-in 3.079 HRD-in -83.8, -49.69 80.24, -45.58 in-in-out SNCiio in-out ActLoopNT-in 2.906 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -121.16, 48.46 APE9-dihe-in -74.89, 156.25 APE8-dihe-in -72.87, 137.28 APE8-rot-na 354.01 APE67-dihe-in -82.99, -1.84 -93.81, -9.25 APE12-dist-na 10.806 APE11-dist-na 10.812 APE10-dist-na 13.419 APE9-dist-out 8.918 None None None XRAY 2.4 0.214 0.256 B 294 278 12 0 0 0 [[521, 779], [822, 1097]] 2.0 7apg TYR_JAK3-2_HUMAN TYR 4e-80 274.8 1 260 260 966 967 968 970 972 855 871 875 946 948 947 949 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 7APGC P52333 812 1103 1124.0 RQT:61201 Type1 Inactive DFGin 6.057 14.05 BLAminus -143.35, -172.89 56.23, 84.96 -97.07, 24.64 284.44, 74.77 -64.51, -25.55 in-in in 8.468 Saltbr-in 3.067 HRD-in -82.68, -50.65 80.68, -46.32 in-in-out SNCiio in-out ActLoopNT-in 2.912 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -120.01, 55.65 APE9-dihe-in -74.89, 157.1 APE8-dihe-in -74.45, 136.81 APE8-rot-na 351.06 APE67-dihe-in -81.76, -1.91 -93.74, -14.98 APE12-dist-na 10.548 APE11-dist-na 11.162 APE10-dist-na 13.963 APE9-dist-out 8.948 None None None XRAY 2.4 0.214 0.256 C 294 287 5 0 0 0 [[521, 779], [822, 1097]] 2.0 7apg TYR_JAK3-2_HUMAN TYR 4e-80 274.8 1 260 260 966 967 968 970 972 855 871 875 946 948 947 949 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 7APGD P52333 815 1103 1124.0 RQT:61201 Type1 Inactive DFGin 6.009 14.041 BLAminus -143.73, -171.03 51.78, 85.49 -96.62, 26.59 283.85, 72.76 -64.13, -26.23 in-in in 8.434 Saltbr-in 3.087 HRD-in -83.66, -49.57 81.52, -47.38 in-in-out SNCiio in-out ActLoopNT-in 2.915 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -120.66, 45.43 APE9-dihe-in -76.74, 156.2 APE8-dihe-in -73.01, 137.72 APE8-rot-na 354.08 APE67-dihe-in -79.85, -1.41 -95.44, -12.08 APE12-dist-na 10.837 APE11-dist-na 10.537 APE10-dist-na 13.236 APE9-dist-out 8.958 None None None XRAY 2.4 0.214 0.256 D 294 277 12 0 0 0 [[521, 779], [822, 1097]] 2.0 7apg TYR_JAK3-2_HUMAN TYR 4e-80 274.8 1 260 260 966 967 968 970 972 855 871 875 946 948 947 949 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3

PDB: 7APG — TYR JAK3_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 7APGC
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK3-2 JAK3_HUMAN 7APGA P52333 813 1103 1124.0 RQT:61201 Type1 Inactive DFGin 6.031 13.952 BLAminus -145.19, -172.66 53.39, 85.17 -97.7, 25.99 284.4, 73.93 -62.87, -25.47 in-in in 8.492 Saltbr-in 3.089 HRD-in -83.97, -50.23 79.99, -46.84 in-in-out SNCiio in-out ActLoopNT-in 2.913 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -120.14, 50.45 APE9-dihe-in -76.86, 156.83 APE8-dihe-in -73.67, 136.77 APE8-rot-na 351.29 APE67-dihe-in -81.27, -2.59 -94.73, -13.37 APE12-dist-na 10.678 APE11-dist-na 10.899 APE10-dist-na 13.601 APE9-dist-out 8.985 None None None XRAY 2.4 0.214 0.256 A 294 279 12 0 0 0 [[521, 779], [822, 1097]] 2.0 7apg Homo sapiens TYR_JAK3-2_HUMAN TYR 4e-80 274.8 1 260 260 966 967 968 970 972 855 871 875 946 948 947 949 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 7APGB P52333 814 1103 1124.0 RQT:61201 Type1 Inactive DFGin 6.039 14.069 BLAminus -144.05, -171.58 55.33, 84.79 -97.11, 25.47 284.03, 75.74 -64.12, -25.92 in-in in 8.44 Saltbr-in 3.079 HRD-in -83.8, -49.69 80.24, -45.58 in-in-out SNCiio in-out ActLoopNT-in 2.906 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -121.16, 48.46 APE9-dihe-in -74.89, 156.25 APE8-dihe-in -72.87, 137.28 APE8-rot-na 354.01 APE67-dihe-in -82.99, -1.84 -93.81, -9.25 APE12-dist-na 10.806 APE11-dist-na 10.812 APE10-dist-na 13.419 APE9-dist-out 8.918 None None None XRAY 2.4 0.214 0.256 B 294 278 12 0 0 0 [[521, 779], [822, 1097]] 2.0 7apg Homo sapiens TYR_JAK3-2_HUMAN TYR 4e-80 274.8 1 260 260 966 967 968 970 972 855 871 875 946 948 947 949 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 7APGC P52333 812 1103 1124.0 RQT:61201 Type1 Inactive DFGin 6.057 14.05 BLAminus -143.35, -172.89 56.23, 84.96 -97.07, 24.64 284.44, 74.77 -64.51, -25.55 in-in in 8.468 Saltbr-in 3.067 HRD-in -82.68, -50.65 80.68, -46.32 in-in-out SNCiio in-out ActLoopNT-in 2.912 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -120.01, 55.65 APE9-dihe-in -74.89, 157.1 APE8-dihe-in -74.45, 136.81 APE8-rot-na 351.06 APE67-dihe-in -81.76, -1.91 -93.74, -14.98 APE12-dist-na 10.548 APE11-dist-na 11.162 APE10-dist-na 13.963 APE9-dist-out 8.948 None None None XRAY 2.4 0.214 0.256 C 294 287 5 0 0 0 [[521, 779], [822, 1097]] 2.0 7apg Homo sapiens TYR_JAK3-2_HUMAN TYR 4e-80 274.8 1 260 260 966 967 968 970 972 855 871 875 946 948 947 949 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 7APGD P52333 815 1103 1124.0 RQT:61201 Type1 Inactive DFGin 6.009 14.041 BLAminus -143.73, -171.03 51.78, 85.49 -96.62, 26.59 283.85, 72.76 -64.13, -26.23 in-in in 8.434 Saltbr-in 3.087 HRD-in -83.66, -49.57 81.52, -47.38 in-in-out SNCiio in-out ActLoopNT-in 2.915 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -120.66, 45.43 APE9-dihe-in -76.74, 156.2 APE8-dihe-in -73.01, 137.72 APE8-rot-na 354.08 APE67-dihe-in -79.85, -1.41 -95.44, -12.08 APE12-dist-na 10.837 APE11-dist-na 10.537 APE10-dist-na 13.236 APE9-dist-out 8.958 None None None XRAY 2.4 0.214 0.256 D 294 277 12 0 0 0 [[521, 779], [822, 1097]] 2.0 7apg Homo sapiens TYR_JAK3-2_HUMAN TYR 4e-80 274.8 1 260 260 966 967 968 970 972 855 871 875 946 948 947 949 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3

PDB: 7APG — TYR JAK3_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name