PDB: 7AJS — CMGC DYR1A_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7AJSA
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 7AJSA Q13627 148 479 763.0 RKH:60501 Type1 Active DFGin 7.392 14.924 BLAminus -118.68, 165.34 71.79, 87.71 -102.61, 24.08 288.44, 78.59 -63.05, -35.5 in-in in 8.753 Saltbr-in 2.748 HRD-in -60.3, -47.5 67.56, 13.64 in-in-in SNCiii in-in ActLoopNT-in 2.832 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -128.78, 153.94 APE9-dihe-na 77.54, 146.15 APE8-dihe-in -64.0, 138.0 APE8-rot-in 250.19 APE67-dihe-in -60.02, -31.0 -48.17, -52.76 APE12-dist-in 11.961 APE11-dist-in 10.616 APE10-dist-in 6.978 APE9-dist-in 3.153 None PTR321 PTR321 XRAY 2.15 0.163 0.2 A 355 329 3 0 0 0 [[159, 479]] 1.0 7ajs CMGC_DYRK1A_HUMAN CMGC 7.9e-91 310.3 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 7AJSB Q13627 148 479 763.0 RKH:60501 Type1 Active DFGin 7.162 14.64 BLAminus -115.69, 165.45 71.0, 84.62 -94.55, 26.84 288.65, 78.98 -76.35, -12.23 in-in in 8.769 Saltbr-in 2.943 HRD-in -67.11, -52.31 82.14, -1.84 in-in-in SNCiii in-in ActLoopNT-in 2.832 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.36, 162.48 APE9-dihe-na 80.28, 144.7 APE8-dihe-in -73.09, 139.12 APE8-rot-in 302.28 APE67-dihe-in -65.82, -22.22 -51.22, -44.57 APE12-dist-in 12.902 APE11-dist-in 11.077 APE10-dist-in 6.906 APE9-dist-in 3.004 None PTR321 PTR321 XRAY 2.15 0.163 0.2 B 355 326 6 0 0 0 [[159, 479]] 1.0 7ajs CMGC_DYRK1A_HUMAN CMGC 7.9e-91 310.3 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

PDB: 7AJS — CMGC DYR1A_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7AJSA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 7AJSA Q13627 148 479 763.0 RKH:60501 Type1 Active DFGin 7.392 14.924 BLAminus -118.68, 165.34 71.79, 87.71 -102.61, 24.08 288.44, 78.59 -63.05, -35.5 in-in in 8.753 Saltbr-in 2.748 HRD-in -60.3, -47.5 67.56, 13.64 in-in-in SNCiii in-in ActLoopNT-in 2.832 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -128.78, 153.94 APE9-dihe-na 77.54, 146.15 APE8-dihe-in -64.0, 138.0 APE8-rot-in 250.19 APE67-dihe-in -60.02, -31.0 -48.17, -52.76 APE12-dist-in 11.961 APE11-dist-in 10.616 APE10-dist-in 6.978 APE9-dist-in 3.153 None PTR321 PTR321 XRAY 2.15 0.163 0.2 A 355 329 3 0 0 0 [[159, 479]] 1.0 7ajs Homo sapiens CMGC_DYRK1A_HUMAN CMGC 7.9e-91 310.3 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 7AJSB Q13627 148 479 763.0 RKH:60501 Type1 Active DFGin 7.162 14.64 BLAminus -115.69, 165.45 71.0, 84.62 -94.55, 26.84 288.65, 78.98 -76.35, -12.23 in-in in 8.769 Saltbr-in 2.943 HRD-in -67.11, -52.31 82.14, -1.84 in-in-in SNCiii in-in ActLoopNT-in 2.832 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -153.36, 162.48 APE9-dihe-na 80.28, 144.7 APE8-dihe-in -73.09, 139.12 APE8-rot-in 302.28 APE67-dihe-in -65.82, -22.22 -51.22, -44.57 APE12-dist-in 12.902 APE11-dist-in 11.077 APE10-dist-in 6.906 APE9-dist-in 3.004 None PTR321 PTR321 XRAY 2.15 0.163 0.2 B 355 326 6 0 0 0 [[159, 479]] 1.0 7ajs Homo sapiens CMGC_DYRK1A_HUMAN CMGC 7.9e-91 310.3 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

PDB: 7AJS — CMGC DYR1A_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name