PDB: 7A6K — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 4 100.0% 7A6KA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7A6KA P00533 700 984 1210.0 R28:1101 Type1 Inactive DFGin 5.672 16.532 BLBtrans -113.38, -178.74 66.45, 17.22 -70.85, 135.38 162.57, 71.95 93.0, -13.33 out-out out 13.46 Saltbr-out 13.73 HRD-in -79.28, -53.26 81.06, -6.15 out-out-out SNCooo out-out ActLoopNT-out 7.541 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, 9.43 APE9-dihe-in -71.11, 126.54 APE8-dihe-in -79.69, 67.98 APE8-rot-na 32.03 APE67-dihe-in -70.72, -4.33 -56.41, -46.0 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 11.919 APE9-dist-out 8.412 T790M,V948R None None XRAY 2.0 0.193 0.22 A 333 266 19 0 0 14 [[712, 970]] 1.0 7a6k TYR_EGFR_HUMAN TYR 6.4e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7A6KB P00533 700 982 1210.0 R28:1101 Type1 Inactive DFGin 5.343 15.868 BLBtrans -129.04, -178.67 62.57, 21.81 -71.79, 126.77 154.84, 72.08 83.61, 999.0 out-none out 13.481 Saltbr-none 999.0 HRD-in -76.88, -46.01 73.74, -7.71 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, 133.51 APE9-dihe-in -84.9, 130.78 APE8-dihe-in -77.41, 66.48 APE8-rot-na 31.07 APE67-dihe-in -72.33, -5.85 -61.23, -39.01 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.682 T790M,V948R None None XRAY 2.0 0.193 0.22 B 333 260 23 0 0 17 [[712, 970]] 1.0 7a6k TYR_EGFR_HUMAN TYR 6.4e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7A6KC P00533 700 984 1210.0 R28:1101 Type1 Inactive DFGin 5.484 15.789 BLBtrans -131.64, -174.72 61.99, 29.43 -91.7, 131.8 164.71, 64.61 141.03, 999.0 out-none out 13.417 Saltbr-none 999.0 HRD-in -76.77, -47.52 68.03, -0.55 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, -68.19 APE9-dihe-in -103.13, 125.01 APE8-dihe-in -86.91, 68.74 APE8-rot-na 26.28 APE67-dihe-in -74.92, -1.32 -57.04, -40.43 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.556 T790M,V948R None None XRAY 2.0 0.193 0.22 C 333 262 23 0 0 17 [[712, 970]] 1.0 7a6k TYR_EGFR_HUMAN TYR 6.4e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7A6KD P00533 702 984 1210.0 R28:1101 Type1 Inactive DFGin 5.163 15.725 BLBtrans -125.34, -177.59 58.43, 37.54 -98.25, 128.03 151.98, 71.88 111.44, 999.0 out-out out 13.356 Saltbr-out 9.148 HRD-in -91.6, -48.16 65.02, 0.98 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 116.46 APE8-dihe-in -80.89, 70.4 APE8-rot-na 24.1 APE67-dihe-in -72.66, -6.51 -57.4, -40.86 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.69 T790M,V948R None None XRAY 2.0 0.193 0.22 D 333 255 28 0 0 18 [[712, 970]] 1.0 7a6k TYR_EGFR_HUMAN TYR 6.4e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 7A6K — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 4 100.0% 7A6KA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7A6KA P00533 700 984 1210.0 R28:1101 Type1 Inactive DFGin 5.672 16.532 BLBtrans -113.38, -178.74 66.45, 17.22 -70.85, 135.38 162.57, 71.95 93.0, -13.33 out-out out 13.46 Saltbr-out 13.73 HRD-in -79.28, -53.26 81.06, -6.15 out-out-out SNCooo out-out ActLoopNT-out 7.541 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, 9.43 APE9-dihe-in -71.11, 126.54 APE8-dihe-in -79.69, 67.98 APE8-rot-na 32.03 APE67-dihe-in -70.72, -4.33 -56.41, -46.0 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 11.919 APE9-dist-out 8.412 T790M,V948R None None XRAY 2.0 0.193 0.22 A 333 266 19 0 0 14 [[712, 970]] 1.0 7a6k Homo sapiens TYR_EGFR_HUMAN TYR 6.4e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7A6KB P00533 700 982 1210.0 R28:1101 Type1 Inactive DFGin 5.343 15.868 BLBtrans -129.04, -178.67 62.57, 21.81 -71.79, 126.77 154.84, 72.08 83.61, 999.0 out-none out 13.481 Saltbr-none 999.0 HRD-in -76.88, -46.01 73.74, -7.71 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, 133.51 APE9-dihe-in -84.9, 130.78 APE8-dihe-in -77.41, 66.48 APE8-rot-na 31.07 APE67-dihe-in -72.33, -5.85 -61.23, -39.01 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.682 T790M,V948R None None XRAY 2.0 0.193 0.22 B 333 260 23 0 0 17 [[712, 970]] 1.0 7a6k Homo sapiens TYR_EGFR_HUMAN TYR 6.4e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7A6KC P00533 700 984 1210.0 R28:1101 Type1 Inactive DFGin 5.484 15.789 BLBtrans -131.64, -174.72 61.99, 29.43 -91.7, 131.8 164.71, 64.61 141.03, 999.0 out-none out 13.417 Saltbr-none 999.0 HRD-in -76.77, -47.52 68.03, -0.55 none-none-out SNCnno none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, -68.19 APE9-dihe-in -103.13, 125.01 APE8-dihe-in -86.91, 68.74 APE8-rot-na 26.28 APE67-dihe-in -74.92, -1.32 -57.04, -40.43 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.556 T790M,V948R None None XRAY 2.0 0.193 0.22 C 333 262 23 0 0 17 [[712, 970]] 1.0 7a6k Homo sapiens TYR_EGFR_HUMAN TYR 6.4e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7A6KD P00533 702 984 1210.0 R28:1101 Type1 Inactive DFGin 5.163 15.725 BLBtrans -125.34, -177.59 58.43, 37.54 -98.25, 128.03 151.98, 71.88 111.44, 999.0 out-out out 13.356 Saltbr-out 9.148 HRD-in -91.6, -48.16 65.02, 0.98 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 116.46 APE8-dihe-in -80.89, 70.4 APE8-rot-na 24.1 APE67-dihe-in -72.66, -6.51 -57.4, -40.86 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.69 T790M,V948R None None XRAY 2.0 0.193 0.22 D 333 255 28 0 0 18 [[712, 970]] 1.0 7a6k Homo sapiens TYR_EGFR_HUMAN TYR 6.4e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 7A6K — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name