PDB: 7A4W — CMGC DYR1A_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7A4WA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 7A4WA Q13627 136 481 763.0 QYH:501 Type1 Active DFGin 7.514 14.841 BLAminus -120.3, 168.53 72.59, 81.22 -96.63, 23.6 288.31, 80.09 -71.01, -22.42 in-in in 8.491 Saltbr-in 2.835 HRD-in -59.72, -50.21 79.8, 0.59 in-in-in SNCiii in-in ActLoopNT-in 3.003 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.05, 174.06 APE9-dihe-na 68.15, 147.74 APE8-dihe-in -68.98, 144.2 APE8-rot-in 298.89 APE67-dihe-in -63.8, -25.02 -56.72, -43.13 APE12-dist-in 9.924 APE11-dist-in 12.077 APE10-dist-in 7.536 APE9-dist-in 3.227 None PTR321 PTR321 XRAY 2.7 0.165 0.205 A 382 340 6 0 0 0 [[159, 479]] 1.0 7a4w CMGC_DYRK1A_HUMAN CMGC 1e-90 310.0 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 7A4WB Q13627 134 481 763.0 QYH:501 Type1 Inactive DFGin 7.23 14.867 BLAminus -127.1, 165.63 77.7, 82.87 -96.17, 24.09 286.93, 79.55 -67.49, -32.84 in-in in 8.601 Saltbr-in 2.743 HRD-in -59.27, -48.69 70.77, 5.13 in-in-out SNCiio in-out ActLoopNT-in 2.861 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -89.37, 163.93 APE9-dihe-na 72.54, 147.59 APE8-dihe-in -66.14, 133.19 APE8-rot-in 287.48 APE67-dihe-in -59.02, -29.56 -43.35, -51.99 APE12-dist-out 14.059 APE11-dist-in 12.004 APE10-dist-in 7.669 APE9-dist-in 3.117 None PTR321 PTR321 XRAY 2.7 0.165 0.205 B 382 341 7 0 0 0 [[159, 479]] 1.0 7a4w CMGC_DYRK1A_HUMAN CMGC 1e-90 310.0 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

PDB: 7A4W — CMGC DYR1A_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7A4WA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 7A4WA Q13627 136 481 763.0 QYH:501 Type1 Active DFGin 7.514 14.841 BLAminus -120.3, 168.53 72.59, 81.22 -96.63, 23.6 288.31, 80.09 -71.01, -22.42 in-in in 8.491 Saltbr-in 2.835 HRD-in -59.72, -50.21 79.8, 0.59 in-in-in SNCiii in-in ActLoopNT-in 3.003 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.05, 174.06 APE9-dihe-na 68.15, 147.74 APE8-dihe-in -68.98, 144.2 APE8-rot-in 298.89 APE67-dihe-in -63.8, -25.02 -56.72, -43.13 APE12-dist-in 9.924 APE11-dist-in 12.077 APE10-dist-in 7.536 APE9-dist-in 3.227 None PTR321 PTR321 XRAY 2.7 0.165 0.205 A 382 340 6 0 0 0 [[159, 479]] 1.0 7a4w Homo sapiens CMGC_DYRK1A_HUMAN CMGC 1e-90 310.0 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 7A4WB Q13627 134 481 763.0 QYH:501 Type1 Inactive DFGin 7.23 14.867 BLAminus -127.1, 165.63 77.7, 82.87 -96.17, 24.09 286.93, 79.55 -67.49, -32.84 in-in in 8.601 Saltbr-in 2.743 HRD-in -59.27, -48.69 70.77, 5.13 in-in-out SNCiio in-out ActLoopNT-in 2.861 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -89.37, 163.93 APE9-dihe-na 72.54, 147.59 APE8-dihe-in -66.14, 133.19 APE8-rot-in 287.48 APE67-dihe-in -59.02, -29.56 -43.35, -51.99 APE12-dist-out 14.059 APE11-dist-in 12.004 APE10-dist-in 7.669 APE9-dist-in 3.117 None PTR321 PTR321 XRAY 2.7 0.165 0.205 B 382 341 7 0 0 0 [[159, 479]] 1.0 7a4w Homo sapiens CMGC_DYRK1A_HUMAN CMGC 1e-90 310.0 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

PDB: 7A4W — CMGC DYR1A_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name