PDB: 7A4R — CMGC DYR1A_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7A4RA
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 7A4RA Q13627 148 479 763.0 QY8:60501 Type1 Active DFGin 7.3 14.891 BLAminus -123.91, 164.94 70.73, 83.02 -95.06, 19.69 291.95, 75.45 -62.6, -28.49 in-in in 8.514 Saltbr-in 2.704 HRD-in -61.82, -47.31 74.74, 3.26 in-in-in SNCiii in-in ActLoopNT-in 2.813 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.99, 160.33 APE9-dihe-na 76.72, 147.14 APE8-dihe-in -69.21, 138.67 APE8-rot-in 293.85 APE67-dihe-in -64.87, -21.48 -52.75, -46.28 APE12-dist-in 12.299 APE11-dist-in 11.025 APE10-dist-in 7.23 APE9-dist-in 3.125 None PTR321 PTR321 XRAY 1.8 0.164 0.194 A 355 329 3 0 0 0 [[159, 479]] 1.0 7a4r CMGC_DYRK1A_HUMAN CMGC 7.9e-91 310.3 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 7A4RB Q13627 148 479 763.0 QY8:60501 Type1 Active DFGin 7.208 14.962 BLAminus -119.24, 168.89 69.18, 79.44 -94.17, 25.13 286.75, 83.25 -70.93, -17.0 in-in in 8.768 Saltbr-in 2.72 HRD-in -64.89, -47.68 76.51, 0.83 in-in-in SNCiii in-in ActLoopNT-in 2.773 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -151.84, 166.7 APE9-dihe-na 79.54, 145.8 APE8-dihe-in -71.28, 139.09 APE8-rot-in 294.44 APE67-dihe-in -65.98, -21.95 -52.32, -45.54 APE12-dist-in 12.987 APE11-dist-in 11.288 APE10-dist-in 7.136 APE9-dist-in 3.129 None PTR321 PTR321 XRAY 1.8 0.164 0.194 B 355 326 6 0 0 0 [[159, 479]] 1.0 7a4r CMGC_DYRK1A_HUMAN CMGC 7.9e-91 310.3 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

PDB: 7A4R — CMGC DYR1A_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 7A4RA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 7A4RA Q13627 148 479 763.0 QY8:60501 Type1 Active DFGin 7.3 14.891 BLAminus -123.91, 164.94 70.73, 83.02 -95.06, 19.69 291.95, 75.45 -62.6, -28.49 in-in in 8.514 Saltbr-in 2.704 HRD-in -61.82, -47.31 74.74, 3.26 in-in-in SNCiii in-in ActLoopNT-in 2.813 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.99, 160.33 APE9-dihe-na 76.72, 147.14 APE8-dihe-in -69.21, 138.67 APE8-rot-in 293.85 APE67-dihe-in -64.87, -21.48 -52.75, -46.28 APE12-dist-in 12.299 APE11-dist-in 11.025 APE10-dist-in 7.23 APE9-dist-in 3.125 None PTR321 PTR321 XRAY 1.8 0.164 0.194 A 355 329 3 0 0 0 [[159, 479]] 1.0 7a4r Homo sapiens CMGC_DYRK1A_HUMAN CMGC 7.9e-91 310.3 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 7A4RB Q13627 148 479 763.0 QY8:60501 Type1 Active DFGin 7.208 14.962 BLAminus -119.24, 168.89 69.18, 79.44 -94.17, 25.13 286.75, 83.25 -70.93, -17.0 in-in in 8.768 Saltbr-in 2.72 HRD-in -64.89, -47.68 76.51, 0.83 in-in-in SNCiii in-in ActLoopNT-in 2.773 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -151.84, 166.7 APE9-dihe-na 79.54, 145.8 APE8-dihe-in -71.28, 139.09 APE8-rot-in 294.44 APE67-dihe-in -65.98, -21.95 -52.32, -45.54 APE12-dist-in 12.987 APE11-dist-in 11.288 APE10-dist-in 7.136 APE9-dist-in 3.129 None PTR321 PTR321 XRAY 1.8 0.164 0.194 B 355 326 6 0 0 0 [[159, 479]] 1.0 7a4r Homo sapiens CMGC_DYRK1A_HUMAN CMGC 7.9e-91 310.3 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

PDB: 7A4R — CMGC DYR1A_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name